ENSGALG00000000067


Gallus gallus

Features
Gene ID: ENSGALG00000000067
  
Biological name :SPR
  
Synonyms : sepiapterin reductase / SPR
  
Possible biological names infered from orthology : P35270
  
Species: Gallus gallus
  
Chr. number: 4
Strand: -1
Band:
Gene start: 90447247
Gene end: 90450343
  
Corresponding Affymetrix probe sets: Gga.13308.1.S1_at (Chicken Array)   GgaAffx.26561.1.S1_at (Chicken Array)   GgaAffx.26561.1.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000000091
NCBI entrez gene - 425255     See in Manteia.
RefSeq - XM_423038
swissprot - E1C4L3
Ensembl - ENSGALG00000000067
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 spraENSDARG00000004406Danio rerio
 sprbENSDARG00000058553Danio rerio
 SPRENSG00000116096Homo sapiens
 SprENSMUSG00000033735Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR002347  Short-chain dehydrogenase/reductase SDR
 IPR006393  Sepiapterin reductase
 IPR016040  NAD(P)-binding domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006729 tetrahydrobiopterin biosynthetic process IEA
 biological_processGO:0006809 nitric oxide biosynthetic process IEA
 biological_processGO:0055114 oxidation-reduction process IEA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005829 cytosol IEA
 molecular_functionGO:0004757 sepiapterin reductase activity IEA


Pathways (from Reactome)
Pathway description
Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
eNOS activation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000000067 SPR / sepiapterin reductase / P35270*  / complex
 ENSGALG00000010909 PRKG2 / protein kinase, cGMP-dependent, type II / Q13237*  / reaction






 

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