ENSDARG00000004406


Danio rerio

Features
Gene ID: ENSDARG00000004406
  
Biological name :spra
  
Synonyms : sepiapterin reductase a / spra
  
Possible biological names infered from orthology : P35270 / sepiapterin reductase / SPR
  
Species: Danio rerio
  
Chr. number: 5
Strand: -1
Band:
Gene start: 72129708
Gene end: 72136548
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000002775
NCBI entrez gene - 554136     See in Manteia.
RefSeq - NM_001024430
RefSeq Peptide - NP_001019601
swissprot - F1QWX4
ZFIN ID - ZDB-GENE-050522-412
Ensembl - ENSDARG00000004406
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 SPRENSGALG00000000067Gallus gallus
 SPRENSG00000116096Homo sapiens
 SprENSMUSG00000033735Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
sprb / sepiapterin reductase b / SPR* / P35270* / sepiapterin reductase*ENSDARG0000005855356


Protein motifs (from Interpro)
Interpro ID Name
 IPR002347  Short-chain dehydrogenase/reductase SDR
 IPR006393  Sepiapterin reductase
 IPR016040  NAD(P)-binding domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006729 tetrahydrobiopterin biosynthetic process IEA
 biological_processGO:0055114 oxidation-reduction process IEA
 cellular_componentGO:0005575 cellular_component ND
 molecular_functionGO:0004757 sepiapterin reductase activity IEA


Pathways (from Reactome)
Pathway description
Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
eNOS activation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000004406 spra / sepiapterin reductase a / SPR* / P35270* / sepiapterin reductase*  / complex
 ENSDARG00000058553 sprb / sepiapterin reductase b / SPR* / P35270* / sepiapterin reductase*  / complex
 ENSDARG00000054741 prkg2 / protein kinase, cGMP-dependent, type II / Q13237*  / reaction






 

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