ENSGALG00000000215


Gallus gallus

Features
Gene ID: ENSGALG00000000215
  
Biological name :DCP2
  
Synonyms : DCP2 / decapping mRNA 2
  
Possible biological names infered from orthology : m7GpppN-mRNA hydrolase / Q8IU60 / Q9CYC6
  
Species: Gallus gallus
  
Chr. number: Z
Strand: -1
Band:
Gene start: 45955426
Gene end: 45980081
  
Corresponding Affymetrix probe sets: Gga.14309.1.A1_at (Chicken Array)   Gga.16383.1.S1_at (Chicken Array)   GgaAffx.20241.1.S1_at (Chicken Array)   GgaAffx.20241.1.S1_s_at (Chicken Array)   GgaAffx.25283.1.S1_at (Chicken Array)   GgaAffx.25283.1.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000048294
Ensembl peptide - ENSGALP00000000282
NCBI entrez gene - 769972     See in Manteia.
RefSeq - XM_004949274
RefSeq - XM_004949272
swissprot - F1NS39
swissprot - A0A1D5P6G7
Ensembl - ENSGALG00000000215
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 dcp2ENSDARG00000104242Danio rerio
 DCP2ENSG00000172795Homo sapiens
 Dcp2ENSMUSG00000024472Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000086  NUDIX hydrolase domain
 IPR007722  mRNA decapping protein 2, Box A domain
 IPR015797  NUDIX hydrolase-like domain superfamily
 IPR020084  NUDIX hydrolase, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA IBA
 biological_processGO:0006402 mRNA catabolic process IEA
 biological_processGO:0032211 negative regulation of telomere maintenance via telomerase IEA
 biological_processGO:0071044 histone mRNA catabolic process IEA
 biological_processGO:0090503 RNA phosphodiester bond hydrolysis, exonucleolytic IEA
 biological_processGO:1904872 regulation of telomerase RNA localization to Cajal body IEA
 cellular_componentGO:0000932 P-body IEA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0016442 RISC complex IEA
 cellular_componentGO:0030054 cell junction IEA
 cellular_componentGO:0036464 cytoplasmic ribonucleoprotein granule IEA
 molecular_functionGO:0003723 RNA binding IEA
 molecular_functionGO:0004534 5"-3" exoribonuclease activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0030145 manganese ion binding IEA
 molecular_functionGO:0050072 m7G(5")pppN diphosphatase activity IEA


Pathways (from Reactome)
Pathway description
mRNA decay by 5 to 3 exoribonuclease
Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA
KSRP (KHSRP) binds and destabilizes mRNA


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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