ENSGALG00000000907


Gallus gallus

Features
Gene ID: ENSGALG00000000907
  
Biological name :KARS
  
Synonyms : KARS / lysine--tRNA ligase
  
Possible biological names infered from orthology : lysyl-tRNA synthetase / Q15046 / Q99MN1
  
Species: Gallus gallus
  
Chr. number: 11
Strand: 1
Band:
Gene start: 20108842
Gene end: 20121754
  
Corresponding Affymetrix probe sets: GgaAffx.12139.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000056598
Ensembl peptide - ENSGALP00000063842
Ensembl peptide - ENSGALP00000063628
Ensembl peptide - ENSGALP00000061735
Ensembl peptide - ENSGALP00000060366
Ensembl peptide - ENSGALP00000001332
NCBI entrez gene - 415885     See in Manteia.
RefSeq - NM_001030583
RefSeq - XM_015292604
RefSeq - XM_015292605
RefSeq Peptide - NP_001025754
swissprot - A0A1L1RXP9
swissprot - F1NE72
swissprot - A0A1L1RSF3
swissprot - A0A1L1RNJ6
swissprot - A0A1D5PUJ4
Ensembl - ENSGALG00000000907
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 karsENSDARG00000103799Danio rerio
 KARSENSG00000065427Homo sapiens
 KarsENSMUSG00000031948Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR002313  Lysine-tRNA ligase, class II
 IPR004364  Aminoacyl-tRNA synthetase, class II (D/K/N)
 IPR004365  OB-fold nucleic acid binding domain, AA-tRNA synthetase-type
 IPR006195  Aminoacyl-tRNA synthetase, class II
 IPR012340  Nucleic acid-binding, OB-fold
 IPR018149  Lysyl-tRNA synthetase, class II, C-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000187 activation of MAPK activity IEA
 biological_processGO:0002276 basophil activation involved in immune response IEA
 biological_processGO:0002741 positive regulation of cytokine secretion involved in immune response IEA
 biological_processGO:0006418 tRNA aminoacylation for protein translation IEA
 biological_processGO:0006430 lysyl-tRNA aminoacylation IEA
 biological_processGO:0008285 negative regulation of cell proliferation IEA
 biological_processGO:0010759 positive regulation of macrophage chemotaxis IEA
 biological_processGO:0015966 diadenosine tetraphosphate biosynthetic process IEA
 biological_processGO:0033209 tumor necrosis factor-mediated signaling pathway IEA
 biological_processGO:0043032 positive regulation of macrophage activation IEA
 biological_processGO:0045893 positive regulation of transcription, DNA-templated IEA
 biological_processGO:0070371 ERK1 and ERK2 cascade IEA
 biological_processGO:0070374 positive regulation of ERK1 and ERK2 cascade IEA
 biological_processGO:1900017 positive regulation of cytokine production involved in inflammatory response IEA
 biological_processGO:1900745 positive regulation of p38MAPK cascade IEA
 biological_processGO:1905050 positive regulation of metallopeptidase activity IEA
 cellular_componentGO:0005615 extracellular space IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005739 mitochondrion IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0017101 aminoacyl-tRNA synthetase multienzyme complex IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003877 ATP adenylyltransferase activity IEA
 molecular_functionGO:0004812 aminoacyl-tRNA ligase activity IEA
 molecular_functionGO:0004824 lysine-tRNA ligase activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0042802 identical protein binding IEA
 molecular_functionGO:0042803 protein homodimerization activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr