ENSGALG00000001121


Gallus gallus

Features
Gene ID: ENSGALG00000001121
  
Biological name :SH3GL1
  
Synonyms : Endophilin-A2 / Q8AXV0 / SH3GL1
  
Possible biological names infered from orthology : Q62419 / Q99961 / SH3 domain containing GRB2 like 1, endophilin A2 / SH3-domain GRB2-like 1
  
Species: Gallus gallus
  
Chr. number: 28
Strand: -1
Band:
Gene start: 2505254
Gene end: 2530104
  
Corresponding Affymetrix probe sets: Gga.15009.1.A1_s_at (Chicken Array)   Gga.15009.1.S1_s_at (Chicken Array)   Gga.24.2.S1_a_at (Chicken Array)   Gga.24.3.S1_a_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000001688
NCBI entrez gene - 395202     See in Manteia.
RefSeq - XM_015299917
RefSeq - NM_204529
RefSeq - XM_015299915
RefSeq - XM_015299916
RefSeq Peptide - NP_989860
swissprot - Q8AXV0
Ensembl - ENSGALG00000001121
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 sh3gl1aENSDARG00000067958Danio rerio
 sh3gl1bENSDARG00000002642Danio rerio
 Q99961ENSG00000141985Homo sapiens
 Q62419ENSMUSG00000003200Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q8AXV1 / SH3GL2 / Endophilin-A1 / Q99962* / Q62420* / SH3-domain GRB2-like 2* / SH3 domain containing GRB2 like 2, endophilin A1*ENSGALG0000001509672
SH3GL3 / endophilin-A3 / Q99963* / endophilin-A3 isoform 3 * / SH3 domain containing GRB2 like 3, endophilin A3*ENSGALG0000000604571
Q5ZIR1 / SH3GLB1 / Endophilin-B1 / Q9JK48* / Q9Y371* / SH3 domain containing GRB2 like, endophilin B1*ENSGALG0000000628425
Q5ZJ81 / SH3GLB2 / Endophilin-B2 / Q9NR46* / Q8R3V5* / SH3-domain GRB2-like endophilin B2* / SH3 domain containing GRB2 like, endophilin B2*ENSGALG0000003954124


Protein motifs (from Interpro)
Interpro ID Name
 IPR001452  SH3 domain
 IPR004148  BAR domain
 IPR027267  AH/BAR domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006897 endocytosis IEA
 biological_processGO:0016191 synaptic vesicle uncoating IEA
 cellular_componentGO:0002102 podosome IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005768 endosome IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0030054 cell junction IEA
 cellular_componentGO:0031901 early endosome membrane IEA
 cellular_componentGO:0042995 cell projection IEA
 cellular_componentGO:0045202 synapse IEA
 molecular_functionGO:0008289 lipid binding IEA
 molecular_functionGO:0042802 identical protein binding IEA
 molecular_functionGO:0045296 cadherin binding IEA


Pathways (from Reactome)
Pathway description
EGFR downregulation
Negative regulation of MET activity
Cargo recognition for clathrin-mediated endocytosis
Clathrin-mediated endocytosis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000001121 Q8AXV0 / SH3GL1 / Endophilin-A2 / Q99961* / Q62419* / SH3-domain GRB2-like 1* / SH3 domain containing GRB2 like 1, endophilin A2*  / complex






 

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