ENSDARG00000002642


Danio rerio

Features
Gene ID: ENSDARG00000002642
  
Biological name :sh3gl1b
  
Synonyms : SH3-domain GRB2-like 1b / sh3gl1b
  
Possible biological names infered from orthology : Q62419 / Q99961 / SH3 domain containing GRB2 like 1, endophilin A2 / SH3-domain GRB2-like 1 / SH3GL1
  
Species: Danio rerio
  
Chr. number: 8
Strand: -1
Band:
Gene start: 18842278
Gene end: 18880399
  
Corresponding Affymetrix probe sets: Dr.21043.1.S1_at (Zebrafish Array)   NM_201497_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000133533
Ensembl peptide - ENSDARP00000091264
NCBI entrez gene - 378838     See in Manteia.
RefSeq - NM_201497
RefSeq Peptide - NP_958905
swissprot - A0A0R4IGE6
swissprot - Q7ZVA3
ZFIN ID - ZDB-GENE-031001-6
Ensembl - ENSDARG00000002642
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Q8AXV0ENSGALG00000001121Gallus gallus
 Q99961ENSG00000141985Homo sapiens
 Q62419ENSMUSG00000003200Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
sh3gl1a / SH3-domain GRB2-like 1a / Q99961* / SH3GL1* / Q62419* / SH3-domain GRB2-like 1* / SH3 domain containing GRB2 like 1, endophilin A2*ENSDARG0000006795872
sh3gl2a / SH3 domain containing GRB2 like 2a, endophilin A1 / Q99962* / SH3GL2* / Q62420* / SH3-domain GRB2-like 2* / SH3 domain containing GRB2 like 2, endophilin A1*ENSDARG0000002360066
sh3gl3a / SH3-domain GRB2-like 3a / Q99963* / SH3GL3* / endophilin-A3 isoform 3 * / SH3 domain containing GRB2 like 3, endophilin A3*ENSDARG0000001336063
sh3gl3b / SH3-domain GRB2-like 3b / Q99963* / SH3GL3* / endophilin-A3 isoform 3 * / SH3 domain containing GRB2 like 3, endophilin A3*ENSDARG0000000730256
SH3GL2 (1 of many) / SH3 domain containing GRB2 like 2, endophilin A1 / Q99962* / SH3GL2*ENSDARG0000003990146
sh3glb2b / SH3-domain GRB2-like endophilin B2b / Q9NR46* / Q8R3V5* / SH3GLB2* / SH3-domain GRB2-like endophilin B2* / SH3 domain containing GRB2 like, endophilin B2*ENSDARG0000003547026
sh3glb1b / SH3-domain GRB2-like endophilin B1b / Q9JK48* / Q9Y371* / SH3GLB1* / Endophilin-B1 * / SH3 domain containing GRB2 like, endophilin B1*ENSDARG0000001095625
sh3glb2a / SH3-domain GRB2-like endophilin B2a / Q9NR46* / Q8R3V5* / SH3GLB2* / SH3-domain GRB2-like endophilin B2* / SH3 domain containing GRB2 like, endophilin B2*ENSDARG0000000898324
sh3glb1a / SH3-domain GRB2-like endophilin B1a / Q9JK48* / Q9Y371* / SH3GLB1* / Endophilin-B1 * / SH3 domain containing GRB2 like, endophilin B1*ENSDARG0000004529423


Protein motifs (from Interpro)
Interpro ID Name
 IPR001452  SH3 domain
 IPR004148  BAR domain
 IPR027267  AH/BAR domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006897 endocytosis IEA
 cellular_componentGO:0005737 cytoplasm IEA


Pathways (from Reactome)
Pathway description
EGFR downregulation
Negative regulation of MET activity
Cargo recognition for clathrin-mediated endocytosis
Clathrin-mediated endocytosis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000002642 sh3gl1b / SH3-domain GRB2-like 1b / Q99961* / SH3GL1* / Q62419* / SH3-domain GRB2-like 1* / SH3 domain containing GRB2 like 1, endophilin A2*  / complex
 ENSDARG00000067958 sh3gl1a / SH3-domain GRB2-like 1a / Q99961* / SH3GL1* / Q62419* / SH3-domain GRB2-like 1* / SH3 domain containing GRB2 like 1, endophilin A2*  / complex






 

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