ENSGALG00000001157


Gallus gallus

Features
Gene ID: ENSGALG00000001157
  
Biological name :DENND1A
  
Synonyms : DENND1A / DENN domain containing 1A
  
Possible biological names infered from orthology : DENN domain-containing protein 1A / Q8K382 / Q8TEH3
  
Species: Gallus gallus
  
Chr. number: 17
Strand: -1
Band:
Gene start: 9508469
Gene end: 9683772
  
Corresponding Affymetrix probe sets: Gga.15570.1.S1_s_at (Chicken Array)   Gga.15570.2.S1_at (Chicken Array)   Gga.18844.1.S1_s_at (Chicken Array)   GgaAffx.23298.1.S1_s_at (Chicken Array)   GgaAffx.765.1.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000058471
Ensembl peptide - ENSGALP00000062099
Ensembl peptide - ENSGALP00000001738
NCBI entrez gene - 417102     See in Manteia.
RefSeq - XM_015279581
swissprot - A0A1D5PZQ5
swissprot - F1P3R1
swissprot - Q5F440
Ensembl - ENSGALG00000001157
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 dennd1aENSDARG00000014592Danio rerio
 Q8TEH3ENSG00000119522Homo sapiens
 Q8K382ENSMUSG00000035392Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
DENND1B / DENN domain containing 1B / Q3U1T9* / Q6P3S1* / DENN domain-containing protein 1B *ENSGALG0000000224632
DENND4C / DENN domain containing 4C / A6H8H2* / Q5VZ89* / DENN domain-containing protein 4C *ENSGALG0000001508316
DENND4A / DENN domain containing 4A / Q7Z401*ENSGALG0000004140316
DENND5A / DENN domain containing 5A / Q6IQ26* / Q6PAL8* / DENN domain-containing protein 5A *ENSGALG0000000584012
DENND3 / DENN domain containing 3 / A2RT67* / A2RUS2* / DENN domain-containing protein 3 *ENSGALG0000003138011
DENND2A / DENN domain containing 2A / Q8C4S8* / Q9ULE3* / DENN domain-containing protein 2A *ENSGALG0000001285711
DENND2C / DENN domain containing 2C / Q68D51*ENSGALG0000000203811
DENND2D / DENN domain containing 2D / Q91VV4* / Q9H6A0* / DENN domain-containing protein 2D *ENSGALG0000000015410
MADD / MAP kinase activating death domain / Q8WXG6*ENSGALG0000000818110
A2RSQ0* / Q6ZUT9* / DENND5B* / DENN domain containing 5B* / DENN domain-containing protein 5B *ENSGALG000000129448
ENSGALG000000059277
ENSGALG000000303742
A2RSQ0* / Q6ZUT9* / DENND5B* / DENN domain containing 5B* / DENN domain-containing protein 5B *ENSGALG000000459902


Protein motifs (from Interpro)
Interpro ID Name
 IPR001194  cDENN domain
 IPR005112  dDENN domain
 IPR005113  uDENN domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006897 endocytosis IEA
 biological_processGO:0032456 endocytic recycling IEA
 biological_processGO:0032483 regulation of Rab protein signal transduction IEA
 biological_processGO:0043547 positive regulation of GTPase activity IEA
 biological_processGO:0048488 synaptic vesicle endocytosis IEA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0030136 clathrin-coated vesicle IEA
 cellular_componentGO:0030425 dendrite IEA
 cellular_componentGO:0030665 clathrin-coated vesicle membrane IEA
 cellular_componentGO:0043025 neuronal cell body IEA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IEA
 cellular_componentGO:0045202 synapse IEA
 molecular_functionGO:0017112 Rab guanyl-nucleotide exchange factor activity IEA
 molecular_functionGO:0017124 SH3 domain binding IEA
 molecular_functionGO:0017137 Rab GTPase binding IEA
 molecular_functionGO:0032266 phosphatidylinositol-3-phosphate binding IEA
 molecular_functionGO:1901981 phosphatidylinositol phosphate binding IEA


Pathways (from Reactome)
Pathway description
RAB GEFs exchange GTP for GDP on RABs


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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