ENSGALG00000008181


Gallus gallus

Features
Gene ID: ENSGALG00000008181
  
Biological name :MADD
  
Synonyms : MADD / MAP kinase activating death domain
  
Possible biological names infered from orthology : Q8WXG6
  
Species: Gallus gallus
  
Chr. number: 5
Strand: -1
Band:
Gene start: 23048402
Gene end: 23104246
  
Corresponding Affymetrix probe sets: Gga.18988.1.S1_at (Chicken Array)   GgaAffx.20194.1.S1_at (Chicken Array)   GgaAffx.20194.1.S1_s_at (Chicken Array)   GgaAffx.5152.5.S1_at (Chicken Array)   GgaAffx.5152.5.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000013303
Ensembl peptide - ENSGALP00000047985
NCBI entrez gene - 423184     See in Manteia.
RefSeq - XM_015287184
RefSeq - XM_015287182
RefSeq - XM_015287183
RefSeq - XM_015287154
RefSeq - XM_015287155
RefSeq - XM_015287156
RefSeq - XM_015287157
RefSeq - XM_015287158
RefSeq - XM_015287159
RefSeq - XM_015287160
RefSeq - XM_015287161
RefSeq - XM_015287162
RefSeq - XM_015287163
RefSeq - XM_015287165
RefSeq - XM_015287166
RefSeq - XM_015287167
RefSeq - XM_015287168
RefSeq - XM_015287169
RefSeq - XM_015287170
RefSeq - XM_015287171
RefSeq - XM_015287172
RefSeq - XM_015287173
RefSeq - XM_015287174
RefSeq - XM_015287175
RefSeq - XM_015287176
RefSeq - XM_015287177
RefSeq - XM_015287178
RefSeq - XM_015287179
RefSeq - XM_015287180
RefSeq - XM_015287181
swissprot - E1C5F9
swissprot - A0A1D5P5L4
Ensembl - ENSGALG00000008181
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 maddENSDARG00000003495Danio rerio
 MADDENSG00000110514Homo sapiens
 MaddENSMUSG00000040687Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
DENND4C / DENN domain containing 4C / A6H8H2* / Q5VZ89* / DENN domain-containing protein 4C *ENSGALG0000001508316
DENND4A / DENN domain containing 4A / Q7Z401*ENSGALG0000004140316
DENND5A / DENN domain containing 5A / Q6IQ26* / Q6PAL8* / DENN domain-containing protein 5A *ENSGALG0000000584010
DENND3 / DENN domain containing 3 / A2RT67* / A2RUS2* / DENN domain-containing protein 3 *ENSGALG000000313809
DENND1B / DENN domain containing 1B / Q3U1T9* / Q6P3S1* / DENN domain-containing protein 1B *ENSGALG000000022467
DENND1A / DENN domain containing 1A / Q8K382* / Q8TEH3* / DENN domain-containing protein 1A *ENSGALG000000011577
A2RSQ0* / Q6ZUT9* / DENND5B* / DENN domain containing 5B* / DENN domain-containing protein 5B *ENSGALG000000129446
DENND2A / DENN domain containing 2A / Q8C4S8* / Q9ULE3* / DENN domain-containing protein 2A *ENSGALG000000128576
DENND2D / DENN domain containing 2D / Q91VV4* / Q9H6A0* / DENN domain-containing protein 2D *ENSGALG000000001545
DENND2C / DENN domain containing 2C / Q68D51*ENSGALG000000020385
ENSGALG000000059274
A2RSQ0* / Q6ZUT9* / DENND5B* / DENN domain containing 5B* / DENN domain-containing protein 5B *ENSGALG000000459903
ENSGALG000000303741


Protein motifs (from Interpro)
Interpro ID Name
 IPR001194  cDENN domain
 IPR005112  dDENN domain
 IPR005113  uDENN domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000187 activation of MAPK activity IEA
 biological_processGO:0032483 regulation of Rab protein signal transduction IEA
 biological_processGO:0042981 regulation of apoptotic process IEA
 biological_processGO:0051726 regulation of cell cycle IEA
 biological_processGO:0097194 execution phase of apoptosis IEA
 biological_processGO:1902041 regulation of extrinsic apoptotic signaling pathway via death domain receptors IEA
 biological_processGO:2001236 regulation of extrinsic apoptotic signaling pathway IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0017112 Rab guanyl-nucleotide exchange factor activity IEA


Pathways (from Reactome)
Pathway description
RAB GEFs exchange GTP for GDP on RABs


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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