ENSDARG00000003495


Danio rerio

Features
Gene ID: ENSDARG00000003495
  
Biological name :madd
  
Synonyms : madd / MAP-kinase activating death domain
  
Possible biological names infered from orthology : Q8WXG6
  
Species: Danio rerio
  
Chr. number: 7
Strand: -1
Band:
Gene start: 34317401
Gene end: 34413398
  
Corresponding Affymetrix probe sets: Dr.7846.1.A1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000047207
Ensembl peptide - ENSDARP00000143875
Ensembl peptide - ENSDARP00000142843
Ensembl peptide - ENSDARP00000142765
Ensembl peptide - ENSDARP00000142707
NCBI entrez gene - 100150917     See in Manteia.
RefSeq - XM_021471962
RefSeq - XM_021477887
swissprot - A0A1D5NSM6
swissprot - A0A1D5NSF0
swissprot - A0A1D5NS97
swissprot - E7F6X3
swissprot - A0A286YA84
ZFIN ID - ZDB-GENE-030131-8076
Ensembl - ENSDARG00000003495
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 MADDENSGALG00000008181Gallus gallus
 MADDENSG00000110514Homo sapiens
 MaddENSMUSG00000040687Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
dennd4c / DENN/MADD domain containing 4C / Q5VZ89* / DENN domain containing 4C*ENSDARG0000010276616
dennd4a / DENN/MADD domain containing 4A / Q7Z401* / DENN domain containing 4A*ENSDARG0000006272115
dennd4b / DENN/MADD domain containing 4B / O75064* / Q3U1Y4* / DENN domain containing 4B* / Mus musculus DENN/MADD domain containing 4B (Dennd4b), transcript variant 2, mRNA.*ENSDARG0000010291414
dennd5a / DENN/MADD domain containing 5A / Q6IQ26* / DENN domain containing 5A*ENSDARG000000170069
Q6NXD8 / dennd5b / DENN/MADD domain containing 5B / Q6ZUT9* / A2RSQ0* / DENN domain containing 5B* / DENN domain-containing protein 5B *ENSDARG000000037899
dennd3a / DENN/MADD domain containing 3a / A2RT67* / A2RUS2* / DENND3* / DENN domain containing 3* / DENN domain-containing protein 3 *ENSDARG000000787978
si:dkey-76b14.2 / Q8CFK6* / Q8IV53* / DENND1C* / DENN domain containing 1C* / DENN domain-containing protein 1C *ENSDARG000000785036
st5 / suppression of tumorigenicity 5 / P78524* / Q924W7* / Suppression of tumorigenicity 5 protein *ENSDARG000000373636
dennd2c / DENN/MADD domain containing 2C / Q68D51* / DENN domain containing 2C*ENSDARG000000737386
dennd1a / DENN/MADD domain containing 1A / Q8K382* / Q8TEH3* / DENN domain containing 1A* / DENN domain-containing protein 1A *ENSDARG000000145925
dennd2da / DENN/MADD domain containing 2Da / Q9H6A0* / Q91VV4* / DENND2D* / DENN domain containing 2D* / DENN domain-containing protein 2D *ENSDARG000000586665
dennd2db / DENN/MADD domain containing 2Db / Q9H6A0* / Q91VV4* / DENND2D* / DENN domain containing 2D* / DENN domain-containing protein 2D *ENSDARG000000302505
dennd3b / DENN/MADD domain containing 3b / A2RT67* / A2RUS2* / DENND3* / DENN domain containing 3* / DENN domain-containing protein 3 *ENSDARG000000131534
dennd1b / DENN/MADD domain containing 1B / Q3U1T9* / Q6P3S1* / DENN domain containing 1B* / DENN domain-containing protein 1B *ENSDARG000001018682


Protein motifs (from Interpro)
Interpro ID Name
 IPR001194  cDENN domain
 IPR005112  dDENN domain
 IPR005113  uDENN domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0065009 regulation of molecular function IEA
 biological_processGO:0097194 execution phase of apoptosis IBA
 molecular_functionGO:0017112 Rab guanyl-nucleotide exchange factor activity IBA


Pathways (from Reactome)
Pathway description
Regulation of TNFR1 signaling
RAB GEFs exchange GTP for GDP on RABs


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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