ENSGALG00000001988


Gallus gallus

Features
Gene ID: ENSGALG00000001988
  
Biological name :TXNRD2
  
Synonyms : thioredoxin reductase 2, mitochondrial precursor / TXNRD2
  
Possible biological names infered from orthology : Q9NNW7 / thioredoxin reductase 2
  
Species: Gallus gallus
  
Chr. number: 15
Strand: -1
Band:
Gene start: 1006748
Gene end: 1038156
  
Corresponding Affymetrix probe sets: Gga.17117.1.S1_at (Chicken Array)   GgaAffx.1316.1.S1_at (Chicken Array)   GgaAffx.25362.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000052539
Ensembl peptide - ENSGALP00000003091
NCBI entrez gene - 416782     See in Manteia.
RefSeq - NM_001122691
RefSeq Peptide - NP_001116163
swissprot - F1P4U5
swissprot - A0A1D5PIA6
Ensembl - ENSGALG00000001988
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 txnrd2.1ENSDARG00000094470Danio rerio
 txnrd2.2ENSDARG00000075923Danio rerio
 Q9NNW7ENSG00000184470Homo sapiens
 Txnrd2ENSMUSG00000075704Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
TXNRD3 / thioredoxin reductase 3 / Q86VQ6*ENSGALG0000003936355
TXNRD1 / Gallus gallus thioredoxin reductase 1 (TXNRD1), transcript variant 2, mRNA. / Q16881* / Q9JMH6* / thioredoxin reductase 1*ENSGALG0000003534554
GSR / glutathione-disulfide reductase / P00390* / P47791* / Glutathione reductase, mitochondrial *ENSGALG0000003778134


Protein motifs (from Interpro)
Interpro ID Name
 IPR003953  FAD-dependent oxidoreductase 2, FAD binding domain
 IPR004099  Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
 IPR006338  Thioredoxin/glutathione reductase selenoprotein
 IPR012999  Pyridine nucleotide-disulphide oxidoreductase, class I, active site
 IPR016156  FAD/NAD-linked reductase, dimerisation domain superfamily
 IPR023753  FAD/NAD(P)-binding domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000305 response to oxygen radical IBA
 biological_processGO:0022900 electron transport chain IEA
 biological_processGO:0045454 cell redox homeostasis IBA
 biological_processGO:0055114 oxidation-reduction process IEA
 biological_processGO:0098869 cellular oxidant detoxification IEA
 cellular_componentGO:0005623 cell IEA
 cellular_componentGO:0005739 mitochondrion IBA
 cellular_componentGO:0005829 cytosol IEA
 molecular_functionGO:0004791 thioredoxin-disulfide reductase activity IBA
 molecular_functionGO:0009055 electron transfer activity IEA
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0016668 oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor IEA
 molecular_functionGO:0050660 flavin adenine dinucleotide binding IEA


Pathways (from Reactome)
Pathway description
Detoxification of Reactive Oxygen Species


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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