ENSGALG00000039363


Gallus gallus

Features
Gene ID: ENSGALG00000039363
  
Biological name :TXNRD3
  
Synonyms : thioredoxin reductase 3 / TXNRD3
  
Possible biological names infered from orthology : Q86VQ6
  
Species: Gallus gallus
  
Chr. number: 12
Strand: 1
Band:
Gene start: 10389896
Gene end: 10409620
  
Corresponding Affymetrix probe sets: Gga.7320.1.S1_at (Chicken Array)   Gga.7320.1.S1_s_at (Chicken Array)   Gga.8908.1.S1_at (Chicken Array)   GgaAffx.26777.1.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000044523
Ensembl peptide - ENSGALP00000053567
NCBI entrez gene - 416031     See in Manteia.
RefSeq - NM_001122777
RefSeq Peptide - NP_001116249
swissprot - A0A1D5PL53
swissprot - A0A1D5NVZ3
Ensembl - ENSGALG00000039363
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 txnrd3ENSDARG00000100374Danio rerio
 Q86VQ6ENSG00000197763Homo sapiens
 Txnrd3ENSMUSG00000000811Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
TXNRD1 / Gallus gallus thioredoxin reductase 1 (TXNRD1), transcript variant 2, mRNA. / Q16881* / Q9JMH6* / thioredoxin reductase 1*ENSGALG0000003534563
TXNRD2 / thioredoxin reductase 2, mitochondrial precursor / Q9NNW7* / thioredoxin reductase 2*ENSGALG0000000198845
GSR / glutathione-disulfide reductase / P00390* / P47791* / Glutathione reductase, mitochondrial *ENSGALG0000003778128


Protein motifs (from Interpro)
Interpro ID Name
 IPR002109  Glutaredoxin
 IPR004099  Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
 IPR006338  Thioredoxin/glutathione reductase selenoprotein
 IPR011767  Glutaredoxin active site
 IPR011899  Glutaredoxin, eukaryotic/virial
 IPR012336  Thioredoxin-like fold
 IPR012999  Pyridine nucleotide-disulphide oxidoreductase, class I, active site
 IPR016156  FAD/NAD-linked reductase, dimerisation domain superfamily
 IPR023753  FAD/NAD(P)-binding domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0022900 electron transport chain IEA
 biological_processGO:0045454 cell redox homeostasis IEA
 biological_processGO:0055114 oxidation-reduction process IEA
 biological_processGO:0098869 cellular oxidant detoxification IEA
 cellular_componentGO:0005623 cell IEA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005829 cytosol IEA
 molecular_functionGO:0004791 thioredoxin-disulfide reductase activity IEA
 molecular_functionGO:0009055 electron transfer activity IEA
 molecular_functionGO:0015035 protein disulfide oxidoreductase activity IEA
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0016668 oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor IEA
 molecular_functionGO:0050660 flavin adenine dinucleotide binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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