ENSMUSG00000000811


Mus musculus

Features
Gene ID: ENSMUSG00000000811
  
Biological name :Txnrd3
  
Synonyms : thioredoxin reductase 3 / Txnrd3
  
Possible biological names infered from orthology : Q86VQ6
  
Species: Mus musculus
  
Chr. number: 6
Strand: 1
Band: D1
Gene start: 89643988
Gene end: 89675529
  
Corresponding Affymetrix probe sets: 10539933 (MoGene1.0st)   1423868_at (Mouse Genome 430 2.0 Array)   1423869_s_at (Mouse Genome 430 2.0 Array)   1449623_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000000828
Ensembl peptide - ENSMUSP00000098730
NCBI entrez gene - 232223     See in Manteia.
MGI - MGI:2386711
RefSeq - NM_001178059
RefSeq - NM_001178058
RefSeq - NM_001178060
RefSeq - NM_153162
RefSeq Peptide - NP_001171531
RefSeq Peptide - NP_694802
RefSeq Peptide - NP_001171529
RefSeq Peptide - NP_001171530
swissprot - G3X8P6
swissprot - D3Z0H7
Ensembl - ENSMUSG00000000811
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 txnrd3ENSDARG00000100374Danio rerio
 TXNRD3ENSGALG00000039363Gallus gallus
 Q86VQ6ENSG00000197763Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q9JMH6 / Txnrd1 / thioredoxin reductase 1 / Q16881*ENSMUSG0000002025059
Txnrd2 / thioredoxin reductase 2 / Q9NNW7*ENSMUSG0000007570446
Gsr / P47791 / Glutathione reductase, mitochondrial / P00390* / glutathione-disulfide reductase*ENSMUSG0000003158428


Protein motifs (from Interpro)
Interpro ID Name
 IPR001100  Pyridine nucleotide-disulphide oxidoreductase, class I
 IPR002109  Glutaredoxin
 IPR004099  Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
 IPR006338  Thioredoxin/glutathione reductase selenoprotein
 IPR011899  Glutaredoxin, eukaryotic/virial
 IPR012999  Pyridine nucleotide-disulphide oxidoreductase, class I, active site
 IPR016156  FAD/NAD-linked reductase, dimerisation domain superfamily
 IPR023753  FAD/NAD(P)-binding domain
 IPR036188  FAD/NAD(P)-binding domain superfamily
 IPR036249  Thioredoxin-like superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0022900 electron transport chain IEA
 biological_processGO:0045454 cell redox homeostasis IEA
 biological_processGO:0055114 oxidation-reduction process IEA
 biological_processGO:0098869 cellular oxidant detoxification IEA
 cellular_componentGO:0005623 cell IEA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005829 cytosol IEA
 molecular_functionGO:0004791 thioredoxin-disulfide reductase activity IEA
 molecular_functionGO:0009055 electron transfer activity IEA
 molecular_functionGO:0015035 protein disulfide oxidoreductase activity IEA
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0016668 oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor IEA
 molecular_functionGO:0050660 flavin adenine dinucleotide binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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