ENSGALG00000035345


Gallus gallus

Features
Gene ID: ENSGALG00000035345
  
Biological name :TXNRD1
  
Synonyms : Gallus gallus thioredoxin reductase 1 (TXNRD1), transcript variant 2, mRNA. / TXNRD1
  
Possible biological names infered from orthology : Q16881 / Q9JMH6 / thioredoxin reductase 1
  
Species: Gallus gallus
  
Chr. number: 1
Strand: -1
Band:
Gene start: 54632776
Gene end: 54671332
  
Corresponding Affymetrix probe sets: GgaAffx.8063.3.S1_at (Chicken Array)   GgaAffx.8063.4.S1_at (Chicken Array)   GgaAffx.8063.5.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000048371
Ensembl peptide - ENSGALP00000057732
NCBI entrez gene - 418082     See in Manteia.
RefSeq - NM_001030762
RefSeq - NM_001352023
RefSeq Peptide - NP_001025933
RefSeq Peptide - NP_001338952
swissprot - A0A1D5PXN5
swissprot - A0A1D5P6P3
Ensembl - ENSGALG00000035345
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Q16881ENSG00000198431Homo sapiens
 Q9JMH6ENSMUSG00000020250Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
TXNRD3 / thioredoxin reductase 3 / Q86VQ6*ENSGALG0000003936372
TXNRD2 / thioredoxin reductase 2, mitochondrial precursor / Q9NNW7* / thioredoxin reductase 2*ENSGALG0000000198850
GSR / glutathione-disulfide reductase / P00390* / P47791* / Glutathione reductase, mitochondrial *ENSGALG0000003778131


Protein motifs (from Interpro)
Interpro ID Name
 IPR004099  Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
 IPR006338  Thioredoxin/glutathione reductase selenoprotein
 IPR012999  Pyridine nucleotide-disulphide oxidoreductase, class I, active site
 IPR016156  FAD/NAD-linked reductase, dimerisation domain superfamily
 IPR023753  FAD/NAD(P)-binding domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001707 mesoderm formation IEA
 biological_processGO:0007369 gastrulation IEA
 biological_processGO:0008283 cell proliferation IEA
 biological_processGO:0022900 electron transport chain IEA
 biological_processGO:0045454 cell redox homeostasis IEA
 biological_processGO:0055114 oxidation-reduction process IEA
 biological_processGO:0098869 cellular oxidant detoxification IEA
 cellular_componentGO:0001650 fibrillar center IEA
 cellular_componentGO:0005623 cell IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005739 mitochondrion IEA
 cellular_componentGO:0005829 cytosol IEA
 molecular_functionGO:0004791 thioredoxin-disulfide reductase activity IEA
 molecular_functionGO:0009055 electron transfer activity IEA
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0016668 oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor IEA
 molecular_functionGO:0050660 flavin adenine dinucleotide binding IEA


Pathways (from Reactome)
Pathway description
Detoxification of Reactive Oxygen Species
Interconversion of nucleotide di- and triphosphates
Metabolism of ingested MeSeO2H into MeSeH
TP53 Regulates Metabolic Genes


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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