ENSGALG00000002022


Gallus gallus

Features
Gene ID: ENSGALG00000002022
  
Biological name :B4GALT1
  
Synonyms : B4GALT1 / beta-1,4-galactosyltransferase 1
  
Possible biological names infered from orthology : Beta-1,4-galactosyltransferase 1 Lactose synthase A protein N-acetyllactosamine synthase Beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase Beta-N-acetylglucosaminyl-glycolipid beta-1,4-galactosyltransferase Processed beta-1,4-galactosyltransferase 1 / P15291 / P15535
  
Species: Gallus gallus
  
Chr. number: Z
Strand: -1
Band:
Gene start: 70633213
Gene end: 70650559
  
Corresponding Affymetrix probe sets: Gga.2840.1.S1_at (Chicken Array)   Gga.5067.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000029057
NCBI entrez gene - 396121     See in Manteia.
RefSeq - NM_205202
RefSeq - XM_015280592
RefSeq Peptide - NP_990533
swissprot - Q92074
Ensembl - ENSGALG00000002022
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 b4galt1ENSDARG00000002634Danio rerio
 P15291ENSG00000086062Homo sapiens
 P15535ENSMUSG00000028413Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
B4GALT2 / beta-1,4-galactosyltransferase 2 / O60909* / Q9Z2Y2* / Beta-1,4-galactosyltransferase 2 Lactose synthase A protein N-acetyllactosamine synthase Beta-N-acetylglucosaminylglycopept...ENSGALG0000001009451
B4GALT4 / beta-1,4-galactosyltransferase 4 / O60513* / Q9JJ04* / Beta-1,4-galactosyltransferase 4 N-acetyllactosamine synthase Lactotriaosylceramide beta-1,4-galactosyltransferase*ENSGALG0000001506941
B4GALT6 / beta-1,4-galactosyltransferase 6 / Q9UBX8* / Q9WVK5* / Beta-1,4-galactosyltransferase 6 Glucosylceramide beta-1,4-galactosyltransferase*ENSGALG0000001515135
ENSGALG0000002289135
O43286* / Q9JMK0* / B4GALT5* / beta-1,4-galactosyltransferase 5*ENSGALG0000000805633
B4GALT7 / beta-1,4-galactosyltransferase 7 / Q8R087* / Q9UBV7* / Beta-1,4-galactosyltransferase 7 Xylosylprotein 4-beta-galactosyltransferase*ENSGALG0000003214523


Protein motifs (from Interpro)
Interpro ID Name
 IPR003859  Beta-1,4-galactosyltransferase
 IPR027791  Galactosyltransferase, C-terminal
 IPR027995  Galactosyltransferase, N-terminal
 IPR029044  Nucleotide-diphospho-sugar transferases


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002064 epithelial cell development IEA
 biological_processGO:0002526 acute inflammatory response IEA
 biological_processGO:0005975 carbohydrate metabolic process IEA
 biological_processGO:0005989 lactose biosynthetic process IEA
 biological_processGO:0006012 galactose metabolic process IEA
 biological_processGO:0006486 protein glycosylation IEA
 biological_processGO:0006487 protein N-linked glycosylation IEA
 biological_processGO:0007155 cell adhesion IEA
 biological_processGO:0007339 binding of sperm to zona pellucida IEA
 biological_processGO:0007341 penetration of zona pellucida IEA
 biological_processGO:0008285 negative regulation of cell proliferation IEA
 biological_processGO:0009101 glycoprotein biosynthetic process IEA
 biological_processGO:0009312 oligosaccharide biosynthetic process IEA
 biological_processGO:0030198 extracellular matrix organization IEA
 biological_processGO:0030879 mammary gland development IEA
 biological_processGO:0042060 wound healing IEA
 biological_processGO:0042127 regulation of cell proliferation IEA
 biological_processGO:0043065 positive regulation of apoptotic process IEA
 biological_processGO:0045136 development of secondary sexual characteristics IEA
 biological_processGO:0048754 branching morphogenesis of an epithelial tube IEA
 biological_processGO:0050900 leukocyte migration IEA
 biological_processGO:0051260 protein homooligomerization IEA
 biological_processGO:0051270 regulation of cellular component movement IEA
 biological_processGO:0060046 regulation of acrosome reaction IEA
 biological_processGO:0060054 positive regulation of epithelial cell proliferation involved in wound healing IEA
 biological_processGO:0060055 angiogenesis involved in wound healing IEA
 biological_processGO:0060058 positive regulation of apoptotic process involved in mammary gland involution IEA
 cellular_componentGO:0000138 Golgi trans cisterna IEA
 cellular_componentGO:0005615 extracellular space IEA
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0009897 external side of plasma membrane IEA
 cellular_componentGO:0009986 cell surface IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0016323 basolateral plasma membrane IEA
 cellular_componentGO:0030057 desmosome IEA
 cellular_componentGO:0031526 brush border membrane IEA
 molecular_functionGO:0003831 beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity IEA
 molecular_functionGO:0003945 N-acetyllactosamine synthase activity IEA
 molecular_functionGO:0004461 lactose synthase activity IEA
 molecular_functionGO:0008092 cytoskeletal protein binding IEA
 molecular_functionGO:0008378 galactosyltransferase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0016757 transferase activity, transferring glycosyl groups IEA
 molecular_functionGO:0030145 manganese ion binding IEA
 molecular_functionGO:0035250 UDP-galactosyltransferase activity IEA


Pathways (from Reactome)
Pathway description
Interaction With The Zona Pellucida
Keratan sulfate biosynthesis
Neutrophil degranulation
N-Glycan antennae elongation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000013838 Adam4* / Adam24* / Adam25* / ADAM29* / ADAM30* / Adam34* / Adam39* / ADAM20* / ADAM21* / Adam6a* / Adam6b* / Gm4787* / Gm5346* / O43506* / Q9JI76* / Q9R158* / Q9R160* / Q9UKF2* / Q9UKF5* / ...  / reaction / complex
 ENSGALG00000002022 B4GALT1 / beta-1,4-galactosyltransferase 1 / P15291* / P15535* / Beta-1,4-galactosyltransferase 1 Lactose synthase A protein N-acetyllactosamine synthase Beta-N-acetylglucosaminylglycopepti...  / complex






 

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