ENSGALG00000002024


Gallus gallus

Features
Gene ID: ENSGALG00000002024
  
Biological name :COMT
  
Synonyms : catechol-O-methyltransferase / COMT
  
Possible biological names infered from orthology : O88587 / P21964
  
Species: Gallus gallus
  
Chr. number: 15
Strand: 1
Band:
Gene start: 1049965
Gene end: 1057055
  
Corresponding Affymetrix probe sets: Gga.7199.1.S1_s_at (Chicken Array)   GgaAffx.25365.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000003143
NCBI entrez gene - 416783     See in Manteia.
RefSeq - XM_004945487
RefSeq - XM_004945488
RefSeq - XM_004945489
RefSeq - XM_015275680
RefSeq - XM_415077
RefSeq - XM_001233013
swissprot - E1BTA0
Ensembl - ENSGALG00000002024
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 comtaENSDARG00000015337Danio rerio
 comtbENSDARG00000025679Danio rerio
 COMTENSG00000093010Homo sapiens
 ComtENSMUSG00000000326Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Tomt* / A1Y9I9* / LRTOMT* / Q8WZ04* / Q96E66* / AP000812.4* / Transmembrane O-methyltransferase homolog * / leucine rich transmembrane and O-methyltransferase domain containing*ENSGALG0000003537534


Protein motifs (from Interpro)
Interpro ID Name
 IPR002935  O-methyltransferase, family 3
 IPR017128  Catechol O-methyltransferase, eukaryotic
 IPR029063  S-adenosyl-L-methionine-dependent methyltransferase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006584 catecholamine metabolic process IEA
 biological_processGO:0009712 catechol-containing compound metabolic process IEA
 biological_processGO:0016036 cellular response to phosphate starvation IEA
 biological_processGO:0032259 methylation IEA
 biological_processGO:0042135 neurotransmitter catabolic process IEA
 biological_processGO:0042417 dopamine metabolic process IEA
 biological_processGO:0042420 dopamine catabolic process IEA
 biological_processGO:0042424 catecholamine catabolic process IEA
 cellular_componentGO:0005739 mitochondrion IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IEA
 molecular_functionGO:0000287 magnesium ion binding IEA
 molecular_functionGO:0008171 O-methyltransferase activity IEA
 molecular_functionGO:0016206 catechol O-methyltransferase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Methylation
Enzymatic degradation of dopamine by COMT
Enzymatic degradation of Dopamine by monoamine oxidase


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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