ENSDARG00000015337


Danio rerio

Features
Gene ID: ENSDARG00000015337
  
Biological name :comta
  
Synonyms : catechol-O-methyltransferase a / comta
  
Possible biological names infered from orthology : catechol-O-methyltransferase / COMT / O88587 / P21964
  
Species: Danio rerio
  
Chr. number: 8
Strand: 1
Band:
Gene start: 8459192
Gene end: 8480579
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000024187
Ensembl peptide - ENSDARP00000119183
Ensembl peptide - ENSDARP00000156115
NCBI entrez gene - 561372     See in Manteia.
RefSeq - NM_001030157
RefSeq Peptide - NP_001025328
swissprot - F1QFV7
swissprot - B0UYJ6
swissprot - F4ZGF2
ZFIN ID - ZDB-GENE-050913-117
Ensembl - ENSDARG00000015337
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 COMTENSGALG00000002024Gallus gallus
 COMTENSG00000093010Homo sapiens
 ComtENSMUSG00000000326Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
comtb / catechol-O-methyltransferase b / COMT* / O88587* / P21964* / catechol-O-methyltransferase*ENSDARG0000002567963
tomt / A0A193KX02 / transmembrane O-methyltransferase / LRTOMT* / Q8WZ04* / Q96E66* / AP000812.4* / leucine rich transmembrane and O-methyltransferase domain containing*ENSDARG0000011546334


Protein motifs (from Interpro)
Interpro ID Name
 IPR002935  O-methyltransferase, family 3
 IPR017128  Catechol O-methyltransferase, eukaryotic
 IPR029063  S-adenosyl-L-methionine-dependent methyltransferase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006584 catecholamine metabolic process IEA
 biological_processGO:0032259 methylation IEA
 biological_processGO:0042135 neurotransmitter catabolic process IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0000287 magnesium ion binding IEA
 molecular_functionGO:0008168 methyltransferase activity IEA
 molecular_functionGO:0008171 O-methyltransferase activity IEA
 molecular_functionGO:0016206 catechol O-methyltransferase activity IDA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Methylation
Enzymatic degradation of dopamine by COMT
Enzymatic degradation of Dopamine by monoamine oxidase


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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