ENSGALG00000002424


Gallus gallus

Features
Gene ID: ENSGALG00000002424
  
Biological name :RECQL5
  
Synonyms : RECQL5 / RecQ like helicase 5
  
Possible biological names infered from orthology : ATP-dependent DNA helicase Q5 / O94762 / Q8VID5
  
Species: Gallus gallus
  
Chr. number: 18
Strand: 1
Band:
Gene start: 4833139
Gene end: 4870020
  
Corresponding Affymetrix probe sets: Gga.114.1.S1_at (Chicken Array)   GgaAffx.1626.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000003806
Ensembl peptide - ENSGALP00000064578
Ensembl peptide - ENSGALP00000057786
NCBI entrez gene - 373891     See in Manteia.
RefSeq - NM_204102
RefSeq - XM_015295116
RefSeq - XM_015295117
RefSeq Peptide - NP_989433
swissprot - A0A1L1S0C1
swissprot - A0A1D5PXT9
swissprot - F1NWK5
Ensembl - ENSGALG00000002424
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 recql5ENSDARG00000059556Danio rerio
 O94762ENSG00000108469Homo sapiens
 Q8VID5ENSMUSG00000020752Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
BLM / Bloom syndrome protein homolog / O88700* / P54132* / Bloom syndrome RecQ like helicase*ENSGALG0000000825621
RECQL / ATP-dependent DNA helicase Q1 / Q9Z129* / P46063* / RecQ protein-like* / RecQ like helicase*ENSGALG0000001317417
WRN / Werner syndrome RecQ like helicase / O09053* / Q14191*ENSGALG0000004090917


Protein motifs (from Interpro)
Interpro ID Name
 IPR001650  Helicase, C-terminal
 IPR002464  DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site
 IPR004589  DNA helicase, ATP-dependent, RecQ type
 IPR010716  RecQ helicase-like 5
 IPR011545  DEAD/DEAH box helicase domain
 IPR011991  ArsR-like helix-turn-helix domain
 IPR014001  Helicase superfamily 1/2, ATP-binding domain
 IPR027417  P-loop containing nucleoside triphosphate hydrolase
 IPR032284  ATP-dependent DNA helicase RecQ, zinc-binding domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000278 mitotic cell cycle IEA
 biological_processGO:0000724 double-strand break repair via homologous recombination IBA
 biological_processGO:0006260 DNA replication IEA
 biological_processGO:0006281 DNA repair IEA
 biological_processGO:0006310 DNA recombination IEA
 biological_processGO:0032508 DNA duplex unwinding IEA
 biological_processGO:0034244 negative regulation of transcription elongation from RNA polymerase II promoter IEA
 biological_processGO:0035690 cellular response to drug IEA
 biological_processGO:0051304 chromosome separation IEA
 biological_processGO:0072757 cellular response to camptothecin IEA
 biological_processGO:1990414 replication-born double-strand break repair via sister chromatid exchange IEA
 biological_processGO:2000042 negative regulation of double-strand break repair via homologous recombination IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005694 chromosome IBA
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0016591 DNA-directed RNA polymerase II, holoenzyme IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0000993 RNA polymerase II core binding IEA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003677 DNA binding IBA
 molecular_functionGO:0003678 DNA helicase activity IEA
 molecular_functionGO:0004386 helicase activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0008026 ATP-dependent helicase activity IEA
 molecular_functionGO:0009378 four-way junction helicase activity IBA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0043140 ATP-dependent 3"-5" DNA helicase activity IBA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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