ENSGALG00000008256


Gallus gallus

Features
Gene ID: ENSGALG00000008256
  
Biological name :BLM
  
Synonyms : BLM / Bloom syndrome protein homolog
  
Possible biological names infered from orthology : Bloom syndrome RecQ like helicase / O88700 / P54132
  
Species: Gallus gallus
  
Chr. number: 10
Strand: -1
Band:
Gene start: 19933508
Gene end: 19950517
  
Corresponding Affymetrix probe sets: Gga.1914.1.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000013422
Ensembl peptide - ENSGALP00000063439
Ensembl peptide - ENSGALP00000057438
NCBI entrez gene - 415577     See in Manteia.
RefSeq - NM_001007087
RefSeq Peptide - NP_001007088
swissprot - A0A1L1RX68
swissprot - A0A1D5PWU9
swissprot - F1P3V1
Ensembl - ENSGALG00000008256
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 blmENSDARG00000077089Danio rerio
 BLMENSG00000197299Homo sapiens
 BlmENSMUSG00000030528Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
WRN / Werner syndrome RecQ like helicase / O09053* / Q14191*ENSGALG0000004090918
RECQL / ATP-dependent DNA helicase Q1 / Q9Z129* / P46063* / RecQ protein-like* / RecQ like helicase*ENSGALG0000001317416
RECQL5 / RecQ like helicase 5 / O94762* / Q8VID5* / ATP-dependent DNA helicase Q5 *ENSGALG0000000242416


Protein motifs (from Interpro)
Interpro ID Name
 IPR001650  Helicase, C-terminal
 IPR002121  HRDC domain
 IPR002464  DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site
 IPR004589  DNA helicase, ATP-dependent, RecQ type
 IPR010997  HRDC-like superfamily
 IPR011545  DEAD/DEAH box helicase domain
 IPR011991  ArsR-like helix-turn-helix domain
 IPR012532  BDHCT
 IPR014001  Helicase superfamily 1/2, ATP-binding domain
 IPR018982  RQC domain
 IPR027417  P-loop containing nucleoside triphosphate hydrolase
 IPR032284  ATP-dependent DNA helicase RecQ, zinc-binding domain
 IPR032437  Bloom syndrome protein, N-terminal domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006260 DNA replication IEA
 biological_processGO:0006281 DNA repair IEA
 biological_processGO:0006310 DNA recombination IEA
 biological_processGO:0032508 DNA duplex unwinding IEA
 biological_processGO:0044237 cellular metabolic process IEA
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005634 nucleus IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0008026 ATP-dependent helicase activity IEA
 molecular_functionGO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides IEA
 molecular_functionGO:0043140 ATP-dependent 3"-5" DNA helicase activity IEA


Pathways (from Reactome)
Pathway description
SUMOylation of DNA damage response and repair proteins
HDR through Single Strand Annealing (SSA)
HDR through Homologous Recombination (HRR)
Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)
Resolution of D-loop Structures through Holliday Junction Intermediates
Homologous DNA Pairing and Strand Exchange
Processing of DNA double-strand break ends
Presynaptic phase of homologous DNA pairing and strand exchange


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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