ENSGALG00000002595


Gallus gallus

Features
Gene ID: ENSGALG00000002595
  
Biological name :GPX4
  
Synonyms : glutathione peroxidase 4 / GPX4
  
Possible biological names infered from orthology : O70325 / P36969 / Phospholipid hydroperoxide glutathione peroxidase, mitochondrial
  
Species: Gallus gallus
  
Chr. number: 28
Strand: 1
Band:
Gene start: 2960447
Gene end: 2961818
  
Corresponding Affymetrix probe sets: Gga.107.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000034432
RefSeq - XM_015299984
RefSeq - XM_015299985
swissprot - F1NYU4
Ensembl - ENSGALG00000002595
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 gpx4bENSDARG00000076836Danio rerio
 GPX4ENSG00000167468Homo sapiens
 Gpx4ENSMUSG00000075706Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
GPX2 / glutathione peroxidase 2 / P18283*ENSGALG0000004203138
GPX1 / glutathione peroxidase 1 / P07203* / P11352* / Mus musculus glutathione peroxidase 1 (Gpx1), transcript variant 2, mRNA.*ENSGALG0000002820438
GPX3 / glutathione peroxidase 3 precursor / GPX5* / GPX6* / P22352* / P46412* / P59796* / Q91WR8* / O75715* / P21765* / glutathione peroxidase 5* / glutathione peroxidase 3* / glutathione ...ENSGALG0000000452132
GPX7 / glutathione peroxidase 7 / Q96SL4* / Q99LJ6*ENSGALG0000001063332
GPX8 / glutathione peroxidase 8 (putative) / Q8TED1* / Q9D7B7* / Probable glutathione peroxidase 8 *ENSGALG0000002670430


Protein motifs (from Interpro)
Interpro ID Name
 IPR000889  Glutathione peroxidase
 IPR012336  Thioredoxin-like fold


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006979 response to oxidative stress IEA
 biological_processGO:0051258 protein polymerization IEA
 biological_processGO:0055114 oxidation-reduction process IEA
 biological_processGO:0098869 cellular oxidant detoxification IEA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005739 mitochondrion IEA
 cellular_componentGO:0032991 protein-containing complex IEA
 molecular_functionGO:0004602 glutathione peroxidase activity IEA
 molecular_functionGO:0042802 identical protein binding IEA


Pathways (from Reactome)
Pathway description
Synthesis of 12-eicosatetraenoic acid derivatives
Synthesis of 15-eicosatetraenoic acid derivatives
Biosynthesis of D-series resolvins
Biosynthesis of E-series 18(S)-resolvins
Biosynthesis of aspirin-triggered D-series resolvins
Biosynthesis of E-series 18(R)-resolvins


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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