ENSGALG00000003149


Gallus gallus

Features
Gene ID: ENSGALG00000003149
  
Biological name :ITPR3
  
Synonyms : inositol 1,4,5-trisphosphate receptor type 3 / ITPR3
  
Possible biological names infered from orthology : P70227 / Q14573
  
Species: Gallus gallus
  
Chr. number: 26
Strand: -1
Band:
Gene start: 4622273
Gene end: 4659503
  
Corresponding Affymetrix probe sets: GgaAffx.1993.5.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000004972
NCBI entrez gene - 419910     See in Manteia.
RefSeq - XM_015298987
RefSeq - XM_015298988
RefSeq - XM_418035
swissprot - F1N9Y1
Ensembl - ENSGALG00000003149
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 itpr3ENSDARG00000061741Danio rerio
 ITPR3ENSG00000096433Homo sapiens
 Itpr3ENSMUSG00000042644Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ITPR1 / inositol 1,4,5-trisphosphate receptor type 1 / P11881* / Q14643*ENSGALG0000000829464
ENSGALG0000001407155
RYR2 / ryanodine receptor 2 / E9Q401* / Q92736* / ryanodine receptor 2, cardiac*ENSGALG0000001081223
RYR3 / ryanodine receptor 3 / A2AGL3* / Q15413*ENSGALG0000000970523
ENSGALG000000433017


Protein motifs (from Interpro)
Interpro ID Name
 IPR000493  Inositol 1,4,5-trisphosphate receptor
 IPR000699  RIH domain
 IPR005821  Ion transport domain
 IPR013662  RyR/IP3R Homology associated domain
 IPR014821  Inositol 1,4,5-trisphosphate/ryanodine receptor
 IPR015925  Ryanodine receptor-related
 IPR016024  Armadillo-type fold
 IPR016093  MIR motif


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0006816 calcium ion transport IEA
 biological_processGO:0007613 memory IEA
 biological_processGO:0048016 inositol phosphate-mediated signaling IEA
 biological_processGO:0050913 sensory perception of bitter taste IEA
 biological_processGO:0050916 sensory perception of sweet taste IEA
 biological_processGO:0050917 sensory perception of umami taste IEA
 biological_processGO:0051209 release of sequestered calcium ion into cytosol IBA
 biological_processGO:0051592 response to calcium ion IEA
 biological_processGO:0055085 transmembrane transport IEA
 biological_processGO:0060291 long-term synaptic potentiation IEA
 biological_processGO:0060402 calcium ion transport into cytosol IEA
 biological_processGO:0070588 calcium ion transmembrane transport IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005730 nucleolus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005789 endoplasmic reticulum membrane IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005887 integral component of plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0043235 receptor complex IEA
 molecular_functionGO:0005216 ion channel activity IEA
 molecular_functionGO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity IEA
 molecular_functionGO:0005262 calcium channel activity IEA
 molecular_functionGO:0005509 calcium ion binding IBA
 molecular_functionGO:0015278 calcium-release channel activity IEA
 molecular_functionGO:0035091 phosphatidylinositol binding IEA
 molecular_functionGO:0070679 inositol 1,4,5 trisphosphate binding IEA


Pathways (from Reactome)
Pathway description
Effects of PIP2 hydrolysis
Elevation of cytosolic Ca2+ levels
Glucagon-like Peptide-1 (GLP1) regulates insulin secretion
Ion homeostasis
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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