ENSGALG00000003277


Gallus gallus

Features
Gene ID: ENSGALG00000003277
  
Biological name :SUZ12
  
Synonyms : SUZ12 / SUZ12 polycomb repressive complex 2 subunit
  
Possible biological names infered from orthology : Polycomb protein Suz12 / Q15022 / Q80U70
  
Species: Gallus gallus
  
Chr. number: 18
Strand: 1
Band:
Gene start: 6661442
Gene end: 6678625
  
Corresponding Affymetrix probe sets: Gga.19626.1.S1_s_at (Chicken Array)   Gga.5330.1.S1_at (Chicken Array)   GgaAffx.25792.1.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000005171
Ensembl peptide - ENSGALP00000049960
NCBI entrez gene - 417406     See in Manteia.
RefSeq - XM_004946169
swissprot - A0A1D5PB40
swissprot - F1NLE8
Ensembl - ENSGALG00000003277
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 B0R1D5ENSDARG00000098924Danio rerio
 suz12aENSDARG00000070256Danio rerio
 SUZ12ENSG00000178691Homo sapiens
 Suz12ENSMUSG00000017548Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR019135  Polycomb protein, VEFS-Box


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IBA
 biological_processGO:0008284 positive regulation of cell proliferation IEA
 biological_processGO:0016571 histone methylation IEA
 biological_processGO:0016574 histone ubiquitination IEA
 biological_processGO:0045596 negative regulation of cell differentiation IEA
 biological_processGO:0070734 histone H3-K27 methylation IEA
 cellular_componentGO:0001739 sex chromatin IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005730 nucleolus IEA
 cellular_componentGO:0016586 RSC-type complex IBA
 cellular_componentGO:0016604 nuclear body IEA
 cellular_componentGO:0032993 protein-DNA complex IEA
 cellular_componentGO:0035098 ESC/E(Z) complex IEA
 molecular_functionGO:0000978 RNA polymerase II proximal promoter sequence-specific DNA binding IEA
 molecular_functionGO:0003682 chromatin binding IEA
 molecular_functionGO:0003723 RNA binding IEA
 molecular_functionGO:0031490 chromatin DNA binding IEA
 molecular_functionGO:0035064 methylated histone binding IEA
 molecular_functionGO:0042054 histone methyltransferase activity IEA
 molecular_functionGO:0043565 sequence-specific DNA binding IEA
 molecular_functionGO:0046976 histone methyltransferase activity (H3-K27 specific) IEA
 molecular_functionGO:1990841 promoter-specific chromatin binding IEA


Pathways (from Reactome)
Pathway description
PRC2 methylates histones and DNA
Oxidative Stress Induced Senescence
SUMOylation of chromatin organization proteins
Regulation of PTEN gene transcription
Transcriptional Regulation by E2F6


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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