ENSDARG00000098924


Danio rerio

Features
Gene ID: ENSDARG00000098924
  
Biological name :suz12b
  
Synonyms : B0R1D5 / suz12b / SUZ12 polycomb repressive complex 2b subunit
  
Possible biological names infered from orthology : Polycomb protein Suz12 / Q15022 / Q80U70 / SUZ12 / SUZ12 polycomb repressive complex 2 subunit
  
Species: Danio rerio
  
Chr. number: 6
Strand: 1
Band:
Gene start: 18531932
Gene end: 18544545
  
Corresponding Affymetrix probe sets: Dr.13720.1.S1_at (Zebrafish Array)   Dr.3815.1.A1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000130332
NCBI entrez gene - 561871     See in Manteia.
RefSeq - XM_021476890
RefSeq Peptide - NP_001076293
swissprot - B0R1D5
ZFIN ID - ZDB-GENE-030131-3255
Ensembl - ENSDARG00000098924
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 SUZ12ENSGALG00000003277Gallus gallus
 SUZ12ENSG00000178691Homo sapiens
 Suz12ENSMUSG00000017548Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
suz12a / SUZ12 polycomb repressive complex 2a subunit / SUZ12* / Q80U70* / Q15022* / Polycomb protein Suz12 * / SUZ12 polycomb repressive complex 2 subunit*ENSDARG0000007025668


Protein motifs (from Interpro)
Interpro ID Name
 IPR019135  Polycomb protein, VEFS-Box


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006325 chromatin organization IEA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IBA
 biological_processGO:0016571 histone methylation IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0016586 RSC-type complex IBA
 cellular_componentGO:0035098 ESC/E(Z) complex IBA
 molecular_functionGO:0031490 chromatin DNA binding IBA
 molecular_functionGO:0042054 histone methyltransferase activity IBA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
PRC2 methylates histones and DNA
Oxidative Stress Induced Senescence
SUMOylation of chromatin organization proteins
Regulation of PTEN gene transcription
Transcriptional Regulation by E2F6


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000030756 dnmt1 / DNA (cytosine-5-)-methyltransferase 1 / P26358* / DNA methyltransferase 1*  / reaction / complex
 ENSDARG00000006038 aebp2 / Q7SXV2 / AE binding protein 2 / Q6ZN18* / Q9Z248* / Zinc finger protein AEBP2 *  / complex
 ENSDARG00000044267 sumo1 / Q7SZR5 / small ubiquitin-like modifier 1 / P63166* / P63165* / Small ubiquitin-related modifier 1 *  / complex / reaction
 ENSDARG00000036791 dnmt3bb.1 / DNA (cytosine-5-)-methyltransferase 3 beta, duplicate b.1 / Q9UBC3* / DNMT3B* / Dnmt3c* / O88509* / DNA methyltransferase 3 beta* / DNA (cytosine-5)-methyltransferase 3B *  / complex / reaction
 ENSDARG00000105345 zgc:173552  / reaction / complex
 ENSDARG00000101579 epc1a / enhancer of polycomb homolog 1 (Drosophila) a / EPC1* / Q9H2F5* / enhancer of polycomb homolog 1*  / reaction / complex
 ENSDARG00000052649 Q9DDJ0 / ube2ia / ubiquitin-conjugating enzyme E2Ia / UBE2I* / P63280* / P63279* / ubiquitin conjugating enzyme E2 I*  / reaction
 ENSDARG00000099640 eed / Q566T0 / embryonic ectoderm development / O75530* / Q921E6* / Polycomb protein EED *  / complex
 ENSDARG00000007438 ube2ib / Q9W6H5 / ubiquitin-conjugating enzyme E2Ib / UBE2I* / P63279* / ubiquitin conjugating enzyme E2 I*  / reaction
 ENSDARG00000008119 si:ch211-195d17.2 / E2F6* / O54917* / O75461* / E2F transcription factor 6* / Transcription factor E2F6 *  / reaction / complex
 ENSDARG00000105359 Q4QRF4 / FP325123.1 / Histone H3.2   / reaction / complex
 ENSDARG00000068436 Q6PI20 / h3f3b.1 / H3 histone, family 3B.1 / H3F3B* / H3F3C* / P84243* / Q6NXT2* / H3 histone family member 3C* / H3 histone family member 3B*  / reaction / complex
 ENSDARG00000060054 epc1b / enhancer of polycomb homolog 1 (Drosophila) b / EPC1* / Q9H2F5* / enhancer of polycomb homolog 1*  / complex / reaction
 ENSDARG00000060925 jarid2a / jumonji, AT rich interactive domain 2a / JARID2* / Q62315* / Q92833* / Protein Jumonji * / jumonji and AT-rich interaction domain containing 2*  / complex
 ENSDARG00000078050 phf19 / PHD finger protein 19 / Q5T6S3* / Q9CXG9*  / complex
 ENSDARG00000019293 tfdp1a / transcription factor Dp-1, a / TFDP1* / TFDP3* / Q14186* / Q5H9I0* / Q08639* / transcription factor Dp-1* / transcription factor Dp family member 3*  / complex / reaction
 ENSDARG00000062268 Q1LVC2 / jarid2b / jumonji, AT rich interactive domain 2b / JARID2* / Q62315* / Q92833* / Protein Jumonji * / jumonji and AT-rich interaction domain containing 2*  / complex






 

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