ENSDARG00000008119


Danio rerio

Features
Gene ID: ENSDARG00000008119
  
Biological name :si:ch211-195d17.2
  
Synonyms : si:ch211-195d17.2
  
Possible biological names infered from orthology : E2F6 / E2F transcription factor 6 / O54917 / O75461 / Transcription factor E2F6
  
Species: Danio rerio
  
Chr. number: 20
Strand: -1
Band:
Gene start: 29676874
Gene end: 29683783
  
Corresponding Affymetrix probe sets: Dr.2387.1.A1_at (Zebrafish Array)   NM_001030144_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000020835
Ensembl peptide - ENSDARP00000106693
Ensembl peptide - ENSDARP00000121362
NCBI entrez gene - 560495     See in Manteia.
RefSeq - NM_001030144
RefSeq - XM_005160725
RefSeq Peptide - NP_001025315
swissprot - Q29RF1
swissprot - Q5TZC4
swissprot - F1Q565
ZFIN ID - ZDB-GENE-030131-513
Ensembl - ENSDARG00000008119
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 E2F6ENSGALG00000016454Gallus gallus
 E2F6ENSG00000169016Homo sapiens
 E2f6ENSMUSG00000057469Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
E2F2 / si:ch211-160f23.5 / P56931* / Q14209* / E2F transcription factor 2* / Transcription factor E2F2 *ENSDARG0000007923322
e2f3 / E2F transcription factor 3 / O00716* / O35261* / Transcription factor E2F3 *ENSDARG0000007046321
e2f1 / E2F transcription factor 1 / Q01094*ENSDARG0000010386820
e2f4 / E2F transcription factor 4 / Q16254*ENSDARG0000010157817
e2f5 / E2F transcription factor 5 / Q15329* / Q61502* / Transcription factor E2F5 *ENSDARG0000003881215


Protein motifs (from Interpro)
Interpro ID Name
 IPR003316  E2F/DP family, winged-helix DNA-binding domain
 IPR006612  THAP-type zinc finger
 IPR011991  ArsR-like helix-turn-helix domain
 IPR015633  E2F Family
 IPR015635  Transcription factor E2F6
 IPR032198  E2F transcription factor, CC-MB domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005667 transcription factor complex IEA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IEA
 molecular_functionGO:0046983 protein dimerization activity IEA


Pathways (from Reactome)
Pathway description
Transcriptional Regulation by E2F6


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000003860 cbx3a / chromobox homolog 3a (HP1 gamma homolog, Drosophila) / CBX3* / Q13185* / chromobox 3*  / reaction / complex
 ENSDARG00000069681 pcgf6 / polycomb group ring finger 6 / Q99NA9* / Q9BYE7* / Polycomb group RING finger protein 6 *  / reaction / complex
 ENSDARG00000056079 l3mbtl2 / l(3)mbt-like 2 (Drosophila) / P59178* / Q969R5* / L3MBTL2, polycomb repressive complex 1 subunit* / Lethal(3)malignant brain tumor-like protein 2 *  / complex / reaction
 ENSDARG00000015966 yaf2 / YY1 associated factor 2 / Q8IY57* / Q99LW6*  / reaction / complex
 ENSDARG00000019293 tfdp1a / transcription factor Dp-1, a / TFDP1* / TFDP3* / Q14186* / Q5H9I0* / Q08639* / transcription factor Dp-1* / transcription factor Dp family member 3*  / reaction / complex
 ENSDARG00000010381 rnf2 / Q803I4 / ring finger protein 2 / Q99496* / Q9CQJ4* / E3 ubiquitin-protein ligase RING2 *  / complex / reaction
 ENSDARG00000092158 cbx3b / chromobox homolog 3b / CBX3* / Q13185* / chromobox 3* / chromobox protein homolog 3 *  / reaction / complex
 ENSDARG00000024844 max / myc associated factor X / P61244* / Max protein*  / complex / reaction
 ENSDARG00000060054 epc1b / enhancer of polycomb homolog 1 (Drosophila) b / EPC1* / Q9H2F5* / enhancer of polycomb homolog 1*  / reaction / complex
 ENSDARG00000098924 suz12b / B0R1D5 / SUZ12 polycomb repressive complex 2b subunit / SUZ12* / Q80U70* / Q15022* / Polycomb protein Suz12 * / SUZ12 polycomb repressive complex 2 subunit*  / complex / reaction
 ENSDARG00000101579 epc1a / enhancer of polycomb homolog 1 (Drosophila) a / EPC1* / Q9H2F5* / enhancer of polycomb homolog 1*  / reaction / complex
 ENSDARG00000099640 eed / Q566T0 / embryonic ectoderm development / O75530* / Q921E6* / Polycomb protein EED *  / complex / reaction
 ENSDARG00000104765 chek1 / checkpoint kinase 1 / O14757* / O35280* / Serine/threonine-protein kinase Chk1 *  / reaction






 

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