ENSDARG00000019293


Danio rerio

Features
Gene ID: ENSDARG00000019293
  
Biological name :tfdp1a
  
Synonyms : tfdp1a / transcription factor Dp-1, a
  
Possible biological names infered from orthology : Q08639 / Q14186 / Q5H9I0 / TFDP1 / TFDP3 / transcription factor Dp-1 / transcription factor Dp family member 3
  
Species: Danio rerio
  
Chr. number: 9
Strand: 1
Band:
Gene start: 34950942
Gene end: 34968429
  
Corresponding Affymetrix probe sets: Dr.927.1.S1_at (Zebrafish Array)   NM_213492_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000072266
Ensembl peptide - ENSDARP00000112589
Ensembl peptide - ENSDARP00000105214
NCBI entrez gene - 406813     See in Manteia.
RefSeq - NM_213492
RefSeq Peptide - NP_998657
swissprot - B0V229
swissprot - B0V228
swissprot - Q803N1
ZFIN ID - ZDB-GENE-040426-2883
Ensembl - ENSDARG00000019293
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ENSGALG00000016823Gallus gallus
 TFDP1ENSG00000198176Homo sapiens
 TFDP3ENSG00000183434Homo sapiens
 Tfdp1ENSMUSG00000038482Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
tfdp1b / transcription factor Dp-1, bENSDARG0000001630464
tfdp2 / transcription factor Dp-2 / Q14188*ENSDARG0000004283555


Protein motifs (from Interpro)
Interpro ID Name
 IPR003316  E2F/DP family, winged-helix DNA-binding domain
 IPR011991  ArsR-like helix-turn-helix domain
 IPR014889  Transcription factor DP, C-terminal
 IPR015648  Transcription factor DP
 IPR028313  Transcription factor DP1


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IBA
 biological_processGO:0007049 cell cycle IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005667 transcription factor complex IEA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding IBA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IEA


Pathways (from Reactome)
Pathway description
G0 and Early G1
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
Cyclin D associated events in G1
Transcriptional Regulation by E2F6


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000008119 si:ch211-195d17.2 / E2F6* / O54917* / O75461* / E2F transcription factor 6* / Transcription factor E2F6 *  / complex / reaction
 ENSDARG00000029018 cdkn1ba / cyclin-dependent kinase inhibitor 1Ba / CDKN1B* / P46414* / P46527* / cyclin dependent kinase inhibitor 1B*  / reaction
 ENSDARG00000036096 smad3a / SMAD family member 3a / SMAD3* / Q8BUN5* / P84022* / SMAD family member 3* / Mothers against decapentaplegic homolog 3 *  / complex / reaction
 ENSDARG00000024844 max / myc associated factor X / P61244* / Max protein*  / reaction / complex
 ENSDARG00000006389 smad2 / Q9I9P9 / SMAD family member 2 / Q62432* / Q15796* / Mothers against decapentaplegic homolog 2 *  / reaction / complex
 ENSDARG00000015427 hdac1 / histone deacetylase 1 / O09106* / Q13547* / Gm10093*  / reaction / complex
 ENSDARG00000060054 epc1b / enhancer of polycomb homolog 1 (Drosophila) b / EPC1* / Q9H2F5* / enhancer of polycomb homolog 1*  / reaction / complex
 ENSDARG00000054271 cdkn1bb / cyclin-dependent kinase inhibitor 1Bb / CDKN1B* / P46414* / P46527* / cyclin dependent kinase inhibitor 1B*  / reaction
 ENSDARG00000056079 l3mbtl2 / l(3)mbt-like 2 (Drosophila) / P59178* / Q969R5* / L3MBTL2, polycomb repressive complex 1 subunit* / Lethal(3)malignant brain tumor-like protein 2 *  / reaction / complex
 ENSDARG00000026577 cdk2 / cyclin-dependent kinase 2 / P24941* / P97377*  / reaction / complex
 ENSDARG00000015966 yaf2 / YY1 associated factor 2 / Q8IY57* / Q99LW6*  / complex / reaction
 ENSDARG00000101578 e2f4 / E2F transcription factor 4 / Q16254*  / complex
 ENSDARG00000003860 cbx3a / chromobox homolog 3a (HP1 gamma homolog, Drosophila) / CBX3* / Q13185* / chromobox 3*  / reaction / complex
 ENSDARG00000069681 pcgf6 / polycomb group ring finger 6 / Q99NA9* / Q9BYE7* / Polycomb group RING finger protein 6 *  / reaction / complex
 ENSDARG00000010381 rnf2 / Q803I4 / ring finger protein 2 / Q99496* / Q9CQJ4* / E3 ubiquitin-protein ligase RING2 *  / reaction / complex
 ENSDARG00000070463 e2f3 / E2F transcription factor 3 / O00716* / O35261* / Transcription factor E2F3 *  / complex
 ENSDARG00000079233 E2F2 / si:ch211-160f23.5 / P56931* / Q14209* / E2F transcription factor 2* / Transcription factor E2F2 *  / complex
 ENSDARG00000092158 cbx3b / chromobox homolog 3b / CBX3* / Q13185* / chromobox 3* / chromobox protein homolog 3 *  / reaction / complex
 ENSDARG00000045636 rbl2 / retinoblastoma-like 2 (p130) / Q64700* / Q08999* / Retinoblastoma-like protein 2 * / RB transcriptional corepressor like 2*  / complex
 ENSDARG00000038812 e2f5 / E2F transcription factor 5 / Q15329* / Q61502* / Transcription factor E2F5 *  / complex
 ENSDARG00000075226 smad4a / SMAD family member 4a / SMAD4* / Q13485* / SMAD family member 4*  / complex / reaction
 ENSDARG00000076554 cdkn1a / cyclin-dependent kinase inhibitor 1A / P38936* / P39689* / Cyclin-dependent kinase inhibitor 1 *  / reaction
 ENSDARG00000098924 suz12b / B0R1D5 / SUZ12 polycomb repressive complex 2b subunit / SUZ12* / Q80U70* / Q15022* / Polycomb protein Suz12 * / SUZ12 polycomb repressive complex 2 subunit*  / complex / reaction
 ENSDARG00000101579 epc1a / enhancer of polycomb homolog 1 (Drosophila) a / EPC1* / Q9H2F5* / enhancer of polycomb homolog 1*  / reaction / complex
 ENSDARG00000101637 ccnd1 / Q90459 / cyclin D1 / P24385* / P25322* / G1/S-specific cyclin-D1 *  / reaction
 ENSDARG00000099640 eed / Q566T0 / embryonic ectoderm development / O75530* / Q921E6* / Polycomb protein EED *  / complex / reaction






 

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