ENSDARG00000099640


Danio rerio

Features
Gene ID: ENSDARG00000099640
  
Biological name :eed
  
Synonyms : eed / embryonic ectoderm development / Q566T0
  
Possible biological names infered from orthology : O75530 / Polycomb protein EED / Q921E6
  
Species: Danio rerio
  
Chr. number: 1
Strand: 1
Band:
Gene start: 27690
Gene end: 34330
  
Corresponding Affymetrix probe sets: Dr.14507.1.A1_at (Zebrafish Array)   NM_001017766_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000131820
NCBI entrez gene - 550463     See in Manteia.
RefSeq - NM_001017766
RefSeq Peptide - NP_001017766
swissprot - Q566T0
ZFIN ID - ZDB-GENE-050417-287
Ensembl - ENSDARG00000099640
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 EEDENSGALG00000014060Gallus gallus
 EEDENSG00000074266Homo sapiens
 EedENSMUSG00000030619Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR001680  WD40 repeat
 IPR015943  WD40/YVTN repeat-like-containing domain superfamily
 IPR017986  WD40-repeat-containing domain
 IPR019775  WD40 repeat, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006325 chromatin organization IEA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0016571 histone methylation IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0035098 ESC/E(Z) complex IEA


Pathways (from Reactome)
Pathway description
PRC2 methylates histones and DNA
Oxidative Stress Induced Senescence
Regulation of PTEN gene transcription
Transcriptional Regulation by E2F6


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000030756 dnmt1 / DNA (cytosine-5-)-methyltransferase 1 / P26358* / DNA methyltransferase 1*  / reaction / complex
 ENSDARG00000006038 aebp2 / Q7SXV2 / AE binding protein 2 / Q6ZN18* / Q9Z248* / Zinc finger protein AEBP2 *  / complex
 ENSDARG00000036791 dnmt3bb.1 / DNA (cytosine-5-)-methyltransferase 3 beta, duplicate b.1 / Q9UBC3* / DNMT3B* / Dnmt3c* / O88509* / DNA methyltransferase 3 beta* / DNA (cytosine-5)-methyltransferase 3B *  / complex / reaction
 ENSDARG00000098924 suz12b / B0R1D5 / SUZ12 polycomb repressive complex 2b subunit / SUZ12* / Q80U70* / Q15022* / Polycomb protein Suz12 * / SUZ12 polycomb repressive complex 2 subunit*  / complex
 ENSDARG00000060054 epc1b / enhancer of polycomb homolog 1 (Drosophila) b / EPC1* / Q9H2F5* / enhancer of polycomb homolog 1*  / reaction / complex
 ENSDARG00000101579 epc1a / enhancer of polycomb homolog 1 (Drosophila) a / EPC1* / Q9H2F5* / enhancer of polycomb homolog 1*  / complex / reaction
 ENSDARG00000019293 tfdp1a / transcription factor Dp-1, a / TFDP1* / TFDP3* / Q14186* / Q5H9I0* / Q08639* / transcription factor Dp-1* / transcription factor Dp family member 3*  / reaction / complex
 ENSDARG00000062268 Q1LVC2 / jarid2b / jumonji, AT rich interactive domain 2b / JARID2* / Q62315* / Q92833* / Protein Jumonji * / jumonji and AT-rich interaction domain containing 2*  / complex
 ENSDARG00000008119 si:ch211-195d17.2 / E2F6* / O54917* / O75461* / E2F transcription factor 6* / Transcription factor E2F6 *  / reaction / complex
 ENSDARG00000105359 Q4QRF4 / FP325123.1 / Histone H3.2   / reaction / complex
 ENSDARG00000105345 zgc:173552  / reaction / complex
 ENSDARG00000060925 jarid2a / jumonji, AT rich interactive domain 2a / JARID2* / Q62315* / Q92833* / Protein Jumonji * / jumonji and AT-rich interaction domain containing 2*  / complex
 ENSDARG00000078050 phf19 / PHD finger protein 19 / Q5T6S3* / Q9CXG9*  / complex
 ENSDARG00000068436 Q6PI20 / h3f3b.1 / H3 histone, family 3B.1 / H3F3B* / H3F3C* / P84243* / Q6NXT2* / H3 histone family member 3C* / H3 histone family member 3B*  / reaction / complex






 

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