ENSGALG00000014060


Gallus gallus

Features
Gene ID: ENSGALG00000014060
  
Biological name :EED
  
Synonyms : EED / Polycomb protein EED / Q5ZKH3
  
Possible biological names infered from orthology : embryonic ectoderm development / O75530 / Q921E6
  
Species: Gallus gallus
  
Chr. number: 1
Strand: 1
Band:
Gene start: 190535898
Gene end: 190551879
  
Corresponding Affymetrix probe sets: Gga.8810.1.S1_at (Chicken Array)   GgaAffx.12214.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000022724
Ensembl peptide - ENSGALP00000060607
Ensembl peptide - ENSGALP00000057840
NCBI entrez gene - 426381     See in Manteia.
RefSeq - NM_001031376
RefSeq Peptide - NP_001026547
swissprot - A0A1L1RP86
swissprot - A0A1I7Q420
swissprot - Q5ZKH3
Ensembl - ENSGALG00000014060
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 eedENSDARG00000099640Danio rerio
 EEDENSG00000074266Homo sapiens
 EedENSMUSG00000030619Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR001680  WD40 repeat
 IPR015943  WD40/YVTN repeat-like-containing domain superfamily
 IPR017986  WD40-repeat-containing domain
 IPR019775  WD40 repeat, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IEA
 biological_processGO:0006325 chromatin organization IEA
 biological_processGO:0006349 regulation of gene expression by genetic imprinting IEA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0016571 histone methylation IEA
 biological_processGO:0061087 positive regulation of histone H3-K27 methylation IEA
 biological_processGO:1990830 cellular response to leukemia inhibitory factor IEA
 biological_processGO:2000011 regulation of adaxial/abaxial pattern formation IEA
 cellular_componentGO:0001739 sex chromatin IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0035098 ESC/E(Z) complex IEA
 cellular_componentGO:0045120 pronucleus IEA
 molecular_functionGO:0000978 RNA polymerase II proximal promoter sequence-specific DNA binding IEA
 molecular_functionGO:0003682 chromatin binding IEA
 molecular_functionGO:0042054 histone methyltransferase activity IEA
 molecular_functionGO:0042802 identical protein binding IEA
 molecular_functionGO:0046976 histone methyltransferase activity (H3-K27 specific) IEA


Pathways (from Reactome)
Pathway description
PRC2 methylates histones and DNA
Oxidative Stress Induced Senescence
Regulation of PTEN gene transcription
Transcriptional Regulation by E2F6


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000007169 EPC1 / enhancer of polycomb homolog 1 / Q8C9X6* / Q9H2F5*  / reaction / complex
 ENSGALG00000020078 H3F3C / histone H3.2 / H3.Y* / H3F3B* / H3F3A* / Q6NXT2* / P84243* / P84244* / Histone H3.3 * / H3 histone family member 3B* / H3 histone family member 3A* / H3 histone family member 3C* /...  / complex / reaction
 ENSGALG00000043062 P84229 / HIST2H3D / Histone H3.2 / Q71DI3* / histone cluster 2 H3 family member d*  / complex / reaction
 ENSGALG00000042491 P62801 / Histone H4   / reaction / complex
 ENSGALG00000016454 E2F6 / E2F transcription factor 6 / O54917* / O75461* / Transcription factor E2F6 *  / complex / reaction
 ENSGALG00000016823 TFDP1* / TFDP3* / Q5H9I0* / Q08639* / Q14186* / transcription factor Dp-1* / transcription factor Dp family member 3*  / complex / reaction
 ENSGALG00000043399 EZH2 / enhancer of zeste 2 polycomb repressive complex 2 subunit / Q15910* / Q61188* / Histone-lysine N-methyltransferase EZH2 *  / complex
 ENSGALG00000041461 DNMT3B / DNA methyltransferase 3 beta / Dnmt3c* / Q9UBC3* / O88509* / DNA (cytosine-5)-methyltransferase 3B *  / complex / reaction






 

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