ENSGALG00000020078


Gallus gallus

Features
Gene ID: ENSGALG00000020078
  
Biological name :H3F3C
  
Synonyms : H3F3C / histone H3.2
  
Possible biological names infered from orthology : H3F3A / H3F3B / H3 histone family member 3A / H3 histone family member 3B / H3 histone family member 3C / H3.Y / histone cluster 2, H3c pseudogene / Histone H3.3 / P84243 / P84244 / Q6NXT2
  
Species: Gallus gallus
  
Chr. number: 3
Strand: -1
Band:
Gene start: 17152849
Gene end: 17158938
  
Corresponding Affymetrix probe sets: Gga.5274.2.S1_a_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000031320
Ensembl peptide - ENSGALP00000061455
NCBI entrez gene - 427887     See in Manteia.
RefSeq - NM_001031482
RefSeq - XM_015283737
RefSeq Peptide - NP_001026653
swissprot - A0A1I7Q436
swissprot - A0A1D5PC18
Ensembl - ENSGALG00000020078
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 h3f3cENSDARG00000033009Danio rerio
 h3f3dENSDARG00000045248Danio rerio
 Q6PI20ENSDARG00000020504Danio rerio
 Q6PI20ENSDARG00000068436Danio rerio
 Q6PI20ENSDARG00000068434Danio rerio
 Q803H4ENSDARG00000093022Danio rerio
 H3F3AENSG00000163041Homo sapiens
 H3F3BENSG00000132475Homo sapiens
 H3F3CENSG00000188375Homo sapiens
 H3.YENSG00000269466Homo sapiens
 H3f3aENSMUSG00000060743Mus musculus
 H3f3bENSMUSG00000016559Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
P84229 / HIST2H3L / Histone H3.2 / Q71DI3* / P84228* / HIST2H3A* / Hist2h3b* / histone cluster 2 H3 family member a*ENSGALG0000003896997
P84229 / Histone H3.2 ENSGALG0000004030397
P84229 / Histone H3.2 / P84228* / Hist2h3c1*ENSGALG0000004000497
P84229 / HIST1H3H / Histone H3.2 ENSGALG0000002706497
P84229 / Histone H3.2 / P84228* / Hist1h3d* / Hist1h3f*ENSGALG0000003524497
P84229 / Histone H3.2 ENSGALG0000003793097
P84229 / Histone H3.2 / P84228* / Hist2h3c2*ENSGALG0000003042497
P84229 / HIST2H3D / Histone H3.2 / Q71DI3* / histone cluster 2 H3 family member d*ENSGALG0000004306297
H3F3B / P84247 / Histone H3.3 ENSGALG0000000228668


Protein motifs (from Interpro)
Interpro ID Name
 IPR000164  Histone H3/CENP-A
 IPR007125  Histone H2A/H2B/H3
 IPR009072  Histone-fold


Gene Ontology (GO)
TypeGO IDTermEv.Code
 cellular_componentGO:0000786 nucleosome IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005694 chromosome IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0046982 protein heterodimerization activity IEA


Pathways (from Reactome)
Pathway description
PRC2 methylates histones and DNA
Oxidative Stress Induced Senescence
B-WICH complex positively regulates rRNA expression
Transcriptional regulation by small RNAs
RNA Polymerase I Promoter Opening
RNA Polymerase I Chain Elongation
RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function
Estrogen-dependent gene expression
Factors involved in megakaryocyte development and platelet production


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000002283 MAPKAPK3 / Gallus gallus mitogen-activated protein kinase-activated protein kinase 3 (MAPKAPK3), mRNA. / Q16644* / Q3UMW7* / MAP kinase-activated protein kinase 3 * / mitogen-activated prot...  / reaction
 ENSGALG00000003369 KAT2A / lysine acetyltransferase 2A / Q92830* / Q9JHD2* / K(lysine) acetyltransferase 2A*  / reaction
 ENSGALG00000004570 NCOA3 / nuclear receptor coactivator 3 / Q9Y6Q9*  / complex
 ENSGALG00000002942 JMJD1C / jumonji domain containing 1C / Q15652* / Q69ZK6* / Probable JmjC domain-containing histone demethylation protein 2C *  / reaction
 ENSGALG00000003297 HDAC1 / P56517 / Histone deacetylase 1 / O09106* / Q13547* / Gm10093*  / complex
 ENSGALG00000029270 GATA3 / P23825 / GATA-binding factor 3 / P23771* / P23772* / GATA binding protein 3* / Mus musculus GATA binding protein 3 (Gata3), transcript variant 3, mRNA.*  / complex / reaction
 ENSGALG00000002249 AGO1 / argonaute 1, RISC catalytic component / Q8CJG1* / Q9UL18* / Protein argonaute-1 *  / complex / reaction
 ENSGALG00000011038 CBX3 / Q13185* / chromobox 3* / chromobox protein homolog 3 *  / complex
 ENSGALG00000036856 CBX5 / chromobox 5 / P45973* / Q61686* / Mus musculus chromobox 5 (Cbx5), transcript variant 4, mRNA.*  / reaction / complex
 ENSGALG00000020078 H3F3C / histone H3.2 / H3.Y* / H3F3B* / H3F3A* / Q6NXT2* / P84243* / P84244* / Histone H3.3 * / H3 histone family member 3B* / H3 histone family member 3A* / H3 histone family member 3C* /...  / complex
 ENSGALG00000043399 EZH2 / enhancer of zeste 2 polycomb repressive complex 2 subunit / Q15910* / Q61188* / Histone-lysine N-methyltransferase EZH2 *  / complex / reaction
 ENSGALG00000014060 EED / Q5ZKH3 / Polycomb protein EED / O75530* / Q921E6* / embryonic ectoderm development*  / complex / reaction
 ENSGALG00000042491 P62801 / Histone H4   / complex
 ENSGALG00000043062 P84229 / HIST2H3D / Histone H3.2 / Q71DI3* / histone cluster 2 H3 family member d*  / complex
 ENSGALG00000001644 SIN3A / SIN3 transcription regulator family member A / Q60520* / Q96ST3* / Mus musculus transcriptional regulator, SIN3A (yeast) (Sin3a), transcript variant 4, mRNA.*  / complex
 ENSGALG00000016022 RUNX1 / runt related transcription factor 1 / Q01196*  / complex
 ENSGALG00000033631 MYC / P01109 / Myc proto-oncogene protein / Bmyc* / Q6P8Z1* / P01106* / P01108* / Protein B-Myc * / myelocytomatosis oncogene* / MYC proto-oncogene, bHLH transcription factor*  / complex
 ENSGALG00000011992 EP300 / E1A binding protein p300 / B2RWS6* / Q09472* / Histone acetyltransferase p300 *  / reaction
 ENSGALG00000042833 MAPK14 / mitogen-activated protein kinase 14 / P47811* / Q16539*  / reaction
 ENSGALG00000040023 MAPK11 / mitogen-activated protein kinase 11 / Q15759* / Q9WUI1*  / reaction
 ENSGALG00000032713 FOXA1 / forkhead box A1 / P35582* / P55317* / Hepatocyte nuclear factor 3-alpha *  / reaction / complex
 ENSGALG00000041461 DNMT3B / DNA methyltransferase 3 beta / Dnmt3c* / Q9UBC3* / O88509* / DNA (cytosine-5)-methyltransferase 3B *  / complex / reaction






 

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