ENSGALG00000004570


Gallus gallus

Features
Gene ID: ENSGALG00000004570
  
Biological name :NCOA3
  
Synonyms : NCOA3 / nuclear receptor coactivator 3
  
Possible biological names infered from orthology : Q9Y6Q9
  
Species: Gallus gallus
  
Chr. number: 20
Strand: 1
Band:
Gene start: 6050774
Gene end: 6104515
  
Corresponding Affymetrix probe sets: GgaAffx.2829.1.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000007263
NCBI entrez gene - 419208     See in Manteia.
RefSeq - XM_004947054
RefSeq - XM_004947055
RefSeq - XM_004947056
RefSeq - XM_015296693
RefSeq - XM_015296694
RefSeq - XM_015296695
RefSeq - XM_015296696
RefSeq - XM_015296697
RefSeq - XM_015296698
RefSeq - XM_015296699
RefSeq - XM_015296700
RefSeq - XM_004947051
swissprot - F1NMB5
Ensembl - ENSGALG00000004570
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ncoa3ENSDARG00000077404Danio rerio
 NCOA3ENSG00000124151Homo sapiens
 Ncoa3ENSMUSG00000027678Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
NCOA1 / nuclear receptor coactivator 1 / P70365* / Q15788*ENSGALG0000001661734
NCOA2* / Q15596* / Q61026* / nuclear receptor coactivator 2*ENSGALG0000003601717
NCOA2* / Q15596* / Q61026* / nuclear receptor coactivator 2*ENSGALG0000004599514


Protein motifs (from Interpro)
Interpro ID Name
 IPR000014  PAS domain
 IPR009110  Nuclear receptor coactivator, interlocking
 IPR010011  Domain of unknown function DUF1518
 IPR011598  Myc-type, basic helix-loop-helix (bHLH) domain
 IPR013767  PAS fold
 IPR014920  Nuclear receptor coactivator, Ncoa-type, interlocking
 IPR014935  Nuclear receptor coactivator, receptor-binding domain
 IPR017426  Nuclear receptor coactivator
 IPR028818  Nuclear receptor coactivator 3
 IPR032565  Domain of unknown function DUF4927


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0010628 positive regulation of gene expression IEA
 biological_processGO:0016573 histone acetylation IEA
 biological_processGO:0030522 intracellular receptor signaling pathway IBA
 biological_processGO:0032870 cellular response to hormone stimulus IBA
 biological_processGO:0045618 positive regulation of keratinocyte differentiation IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 biological_processGO:0071392 cellular response to estradiol stimulus IEA
 biological_processGO:2001141 regulation of RNA biosynthetic process IEA
 cellular_componentGO:0000790 nuclear chromatin IEA
 cellular_componentGO:0005634 nucleus IBA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0032991 protein-containing complex IEA
 molecular_functionGO:0003713 transcription coactivator activity IEA
 molecular_functionGO:0004402 histone acetyltransferase activity IEA
 molecular_functionGO:0016922 nuclear receptor binding IEA
 molecular_functionGO:0030374 nuclear receptor transcription coactivator activity IBA
 molecular_functionGO:0035257 nuclear hormone receptor binding IBA
 molecular_functionGO:0046982 protein heterodimerization activity IEA
 molecular_functionGO:0046983 protein dimerization activity IEA
 molecular_functionGO:0047485 protein N-terminus binding IEA
 molecular_functionGO:0097718 disordered domain specific binding IEA


Pathways (from Reactome)
Pathway description
MAPK6/MAPK4 signaling
Estrogen-dependent gene expression


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000010576 GTF2A1 / general transcription factor IIA subunit 1 / P52655* / Q99PM3* / Transcription initiation factor IIA subunit 1 Transcription initiation factor IIA alpha chain Transcription initiat...  / complex / reaction
 ENSGALG00000003793 GTF2A2 / general transcription factor IIA subunit 2 / P52657* / Q80ZM7* / Transcription initiation factor IIA subunit 2 *  / complex / reaction
 ENSGALG00000020078 H3F3C / histone H3.2 / H3.Y* / H3F3B* / H3F3A* / Q6NXT2* / P84243* / P84244* / Histone H3.3 * / H3 histone family member 3B* / H3 histone family member 3A* / H3 histone family member 3C* /...  / complex
 ENSGALG00000032713 FOXA1 / forkhead box A1 / P35582* / P55317* / Hepatocyte nuclear factor 3-alpha *  / complex / reaction
 ENSGALG00000004570 NCOA3 / nuclear receptor coactivator 3 / Q9Y6Q9*  / complex / reaction
 ENSGALG00000029270 GATA3 / P23825 / GATA-binding factor 3 / P23771* / P23772* / GATA binding protein 3* / Mus musculus GATA binding protein 3 (Gata3), transcript variant 3, mRNA.*  / complex / reaction
 ENSGALG00000011171 TBP / TATA-box-binding protein / P20226* / P29037*  / reaction / complex
 ENSGALG00000043062 P84229 / HIST2H3D / Histone H3.2 / Q71DI3* / histone cluster 2 H3 family member d*  / complex
 ENSGALG00000042491 P62801 / Histone H4   / complex
 ENSGALG00000011992 EP300 / E1A binding protein p300 / B2RWS6* / Q09472* / Histone acetyltransferase p300 *  / reaction / complex
 ENSGALG00000031448 MAPK6 / Q5F3W3 / Mitogen-activated protein kinase 6 / Q16659* / Q61532*  / reaction






 

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