ENSGALG00000042491


Gallus gallus

Features
Gene ID: ENSGALG00000042491
  
Biological name :
  
Synonyms : Histone H4 / P62801
  
Possible biological names infered from orthology :
  
Species: Gallus gallus
  
Chr. number: 1
Strand: 1
Band:
Gene start: 48160103
Gene end: 48160539
  
Corresponding Affymetrix probe sets: Gga.5576.1.S1_a_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000049875
NCBI entrez gene - 770005     See in Manteia.
swissprot - P62801
Ensembl - ENSGALG00000042491
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 zgc:165555ENSDARG00000112954Danio rerio


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
P62801 / HIST2H4B / Histone H4 ENSGALG00000032198100
P62801 / HIST1H46L2 / Histone H4 ENSGALG00000035445100
P62801 / Histone H4 ENSGALG00000041398100
P62801 / HIST1H4D / Histone H4 / P62805* / histone cluster 1 H4 family member d*ENSGALG00000032933100
P62801 / HIST1H46 / Histone H4 ENSGALG00000037322100
P62801 / Histone H4 / P62806* / Hist1h4c*ENSGALG00000032272100
P62801 / HIST2H4B / Histone H4 / P62805* / histone cluster 2 H4 family member b*ENSGALG00000025786100


Protein motifs (from Interpro)
Interpro ID Name
 IPR001951  Histone H4
 IPR004823  TATA box binding protein associated factor (TAF)
 IPR009072  Histone-fold
 IPR019809  Histone H4, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006334 nucleosome assembly IBA
 biological_processGO:0006352 DNA-templated transcription, initiation IEA
 cellular_componentGO:0000786 nucleosome IEA
 cellular_componentGO:0000788 nuclear nucleosome IBA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005694 chromosome IEA
 molecular_functionGO:0003677 DNA binding IBA
 molecular_functionGO:0042393 histone binding IBA
 molecular_functionGO:0046982 protein heterodimerization activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000000777 EYA3 / EYA transcriptional coactivator and phosphatase 3 / P97480* / Q99504* / Eyes absent homolog 3 *  / reaction
 ENSGALG00000002283 MAPKAPK3 / Gallus gallus mitogen-activated protein kinase-activated protein kinase 3 (MAPKAPK3), mRNA. / Q16644* / Q3UMW7* / MAP kinase-activated protein kinase 3 * / mitogen-activated prot...  / reaction
 ENSGALG00000003369 KAT2A / lysine acetyltransferase 2A / Q92830* / Q9JHD2* / K(lysine) acetyltransferase 2A*  / reaction
 ENSGALG00000004570 NCOA3 / nuclear receptor coactivator 3 / Q9Y6Q9*  / complex
 ENSGALG00000003325 KMT5A / lysine methyltransferase 5A / Q9NQR1*  / reaction
 ENSGALG00000003297 HDAC1 / P56517 / Histone deacetylase 1 / O09106* / Q13547* / Gm10093*  / complex
 ENSGALG00000006392 RNF168 / ring finger protein 168 / Q80XJ2* / Q8IYW5* / E3 ubiquitin-protein ligase RNF168 *  / complex / reaction
 ENSGALG00000006110 PLK1 / serine/threonine-protein kinase PLK1 / P53350* / Q07832* / polo like kinase 1*  / complex / reaction
 ENSGALG00000008435 SUMO1 / Q8QGH2 / Small ubiquitin-related modifier 1 / P63166* / P63165* / small ubiquitin-like modifier 1*  / reaction / complex
 ENSGALG00000005695 CHEK2 / checkpoint kinase 2 / O96017* / Q9Z265* / Serine/threonine-protein kinase Chk2 *  / complex / reaction
 ENSGALG00000006428 UBE2I / P63283 / SUMO-conjugating enzyme UBC9 / P63280* / P63279* / ubiquitin conjugating enzyme E2 I*  / reaction
 ENSGALG00000020078 H3F3C / histone H3.2 / H3.Y* / H3F3B* / H3F3A* / Q6NXT2* / P84243* / P84244* / Histone H3.3 * / H3 histone family member 3B* / H3 histone family member 3A* / H3 histone family member 3C* /...  / complex
 ENSGALG00000014060 EED / Q5ZKH3 / Polycomb protein EED / O75530* / Q921E6* / embryonic ectoderm development*  / complex / reaction
 ENSGALG00000017159 ATM / ATM serine/threonine kinase / Q13315* / Q62388* / Serine-protein kinase ATM *  / complex
 ENSGALG00000014152 KMT5B / lysine methyltransferase 5B / Q3U8K7* / Q4FZB7* / Histone-lysine N-methyltransferase KMT5B *  / reaction
 ENSGALG00000016739 HERC2 / HECT and RLD domain containing E3 ubiquitin protein ligase 2 / O95714* / Q4U2R1* / E3 ubiquitin-protein ligase HERC2 *  / complex / reaction
 ENSGALG00000017211 MRE11 / double-strand break repair protein MRE11 / Mre11a* / Q61216* / P49959* / MRE11 homolog, double strand break repair nuclease*  / complex
 ENSGALG00000011992 EP300 / E1A binding protein p300 / B2RWS6* / Q09472* / Histone acetyltransferase p300 *  / reaction
 ENSGALG00000015705 NSD2 / nuclear receptor binding SET domain protein 2 / O96028* / Q8BVE8* / Histone-lysine N-methyltransferase NSD2 *  / reaction / complex
 ENSGALG00000028133 UBE2V2 / Q5F3Z3 / Ubiquitin-conjugating enzyme E2 variant 2 / Q9D2M8* / Q15819* / ubiquitin conjugating enzyme E2 V2*  / reaction / complex
 ENSGALG00000012484 RIF1 / E1C2U2 / Telomere-associated protein RIF1 / Q6PR54* / Q5UIP0* / replication timing regulatory factor 1*  / complex / reaction
 ENSGALG00000037716 UBA52 / ubiquitin A-52 residue ribosomal protein fusion product 1 / P62984* / P62987* / Gm5239* / Gm11808* / predicted gene 11808*  / reaction
 ENSGALG00000029270 GATA3 / P23825 / GATA-binding factor 3 / P23771* / P23772* / GATA binding protein 3* / Mus musculus GATA binding protein 3 (Gata3), transcript variant 3, mRNA.*  / reaction / complex
 ENSGALG00000006794 RAD50* / Q92878* / AC116366.3* / RAD50 double strand break repair protein*  / complex
 ENSGALG00000026449 H2AFX* / P16104* / P27661* / Histone H2AX * / H2A histone family member X*  / complex
 ENSGALG00000023256 RNF8 / ring finger protein 8 / O76064* / Q8VC56* / Gm28043* / E3 ubiquitin-protein ligase RNF8 *  / reaction / complex
 ENSGALG00000042833 MAPK14 / mitogen-activated protein kinase 14 / P47811* / Q16539*  / reaction
 ENSGALG00000036790 P79781 / RPS27A / Ubiquitin-40S ribosomal protein S27a Ubiquitin 40S ribosomal protein S27a / P62983* / P62979* / AL136454.1* / ribosomal protein S27a*  / reaction
 ENSGALG00000043062 P84229 / HIST2H3D / Histone H3.2 / Q71DI3* / histone cluster 2 H3 family member d*  / complex
 ENSGALG00000041433 MSL3 / MSL complex subunit 3 / Msl3l2* / Q9WVG9* / Q8N5Y2* / Male-specific lethal 3 homolog *  / reaction
 ENSGALG00000039294 MSL2 / MSL complex subunit 2 / Q69ZF8* / Q9HCI7* / E3 ubiquitin-protein ligase MSL2 *  / reaction
 ENSGALG00000040023 MAPK11 / mitogen-activated protein kinase 11 / Q15759* / Q9WUI1*  / reaction
 ENSGALG00000042491 P62801 / Histone H4   / complex / reaction
 ENSGALG00000007971 SUMO2 / Q5ZJM9 / Small ubiquitin-related modifier 2 / SUMO4* / Q6EEV6* / P61957* / P61956* / small ubiquitin-like modifier 2* / small ubiquitin-like modifier 4*  / reaction / complex
 ENSGALG00000045705 H2AFX* / P16104* / P27661* / Histone H2AX * / H2A histone family member X*  / complex
 ENSGALG00000043399 EZH2 / enhancer of zeste 2 polycomb repressive complex 2 subunit / Q15910* / Q61188* / Histone-lysine N-methyltransferase EZH2 *  / complex / reaction
 ENSGALG00000034413 PIAS4 / protein inhibitor of activated STAT 4 / Q8N2W9* / Q9JM05*  / reaction / complex
 ENSGALG00000039068 RSF1 / remodeling and spacing factor 1 / Q96T23*  / complex
 ENSGALG00000008579 OIP5 / Opa interacting protein 5 / A2AQ14* / O43482* / Protein Mis18-beta *  / complex
 ENSGALG00000009913 SMARCA5 / SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5 / O60264* / Q91ZW3*  / complex
 ENSGALG00000001644 SIN3A / SIN3 transcription regulator family member A / Q60520* / Q96ST3* / Mus musculus transcriptional regulator, SIN3A (yeast) (Sin3a), transcript variant 4, mRNA.*  / complex
 ENSGALG00000011038 CBX3 / Q13185* / chromobox 3* / chromobox protein homolog 3 *  / complex
 ENSGALG00000016022 RUNX1 / runt related transcription factor 1 / Q01196*  / complex
 ENSGALG00000015884 MIS18A / MIS18 kinetochore protein A / Q9CZJ6* / Q9NYP9* / Protein Mis18-alpha *  / complex
 ENSGALG00000002249 AGO1 / argonaute 1, RISC catalytic component / Q8CJG1* / Q9UL18* / Protein argonaute-1 *  / reaction / complex
 ENSGALG00000033631 MYC / P01109 / Myc proto-oncogene protein / Bmyc* / Q6P8Z1* / P01106* / P01108* / Protein B-Myc * / myelocytomatosis oncogene* / MYC proto-oncogene, bHLH transcription factor*  / complex
 ENSGALG00000006109 MAPK8 / mitogen-activated protein kinase 8 / P45983* / Q91Y86*  / reaction / complex
 ENSGALG00000037735 CENPA / histone H3-like centromeric protein A / O35216* / P49450* / centromere protein A*  / complex
 ENSGALG00000032713 FOXA1 / forkhead box A1 / P35582* / P55317* / Hepatocyte nuclear factor 3-alpha *  / complex / reaction
 ENSGALG00000041461 DNMT3B / DNA methyltransferase 3 beta / Dnmt3c* / Q9UBC3* / O88509* / DNA (cytosine-5)-methyltransferase 3B *  / reaction / complex






 

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