ENSGALG00000000777


Gallus gallus

Features
Gene ID: ENSGALG00000000777
  
Biological name :EYA3
  
Synonyms : EYA3 / EYA transcriptional coactivator and phosphatase 3
  
Possible biological names infered from orthology : Eyes absent homolog 3 / P97480 / Q99504
  
Species: Gallus gallus
  
Chr. number: 23
Strand: -1
Band:
Gene start: 1499032
Gene end: 1528963
  
Corresponding Affymetrix probe sets: Gga.1018.1.S1_at (Chicken Array)   Gga.15800.1.S1_at (Chicken Array)   GgaAffx.508.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000001125
NCBI entrez gene - 395717     See in Manteia.
RefSeq - XM_417715
RefSeq - NM_001305166
RefSeq - XM_015297524
RefSeq - XM_015297525
RefSeq - XM_004947697
RefSeq - XM_004947698
RefSeq - XM_004947700
RefSeq - XM_015297520
RefSeq - XM_015297521
RefSeq - XM_015297522
RefSeq - XM_015297523
RefSeq Peptide - NP_001292095
swissprot - F1ND27
Ensembl - ENSGALG00000000777
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 eya3ENSDARG00000036100Danio rerio
 EYA3ENSG00000158161Homo sapiens
 Eya3ENSMUSG00000028886Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
EYA1 / EYA transcriptional coactivator and phosphatase 1 / P97767* / Q99502* / Eyes absent homolog 1 *ENSGALG0000004303342
EYA4 / EYA transcriptional coactivator and phosphatase 4 / O95677* / Q9Z191* / Mus musculus EYA transcriptional coactivator and phosphatase 4 (Eya4), transcript variant 2, mRNA.*ENSGALG0000003165641
EYA2 / Gallus gallus EYA transcriptional coactivator and phosphatase 2 (EYA2), mRNA. / O00167* / O08575* / Eyes absent homolog 2 * / EYA transcriptional coactivator and phosphatase 2*ENSGALG0000000450837
EYA2* / O00167* / O08575* / Eyes absent homolog 2 * / EYA transcriptional coactivator and phosphatase 2*ENSGALG0000004252312


Protein motifs (from Interpro)
Interpro ID Name
 IPR006545  EYA domain
 IPR023214  HAD superfamily
 IPR028472  Eyes absent family
 IPR028479  Eyes absent homologue 3


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006302 double-strand break repair IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0010212 response to ionizing radiation IEA
 biological_processGO:0016576 histone dephosphorylation IEA
 biological_processGO:0035335 peptidyl-tyrosine dephosphorylation IEA
 biological_processGO:0045739 positive regulation of DNA repair IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005667 transcription factor complex IEA
 cellular_componentGO:0005813 centrosome IEA
 molecular_functionGO:0004721 phosphoprotein phosphatase activity IEA
 molecular_functionGO:0004725 protein tyrosine phosphatase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000006794 RAD50* / Q92878* / AC116366.3* / RAD50 double strand break repair protein*  / reaction
 ENSGALG00000045705 H2AFX* / P16104* / P27661* / Histone H2AX * / H2A histone family member X*  / reaction
 ENSGALG00000026449 H2AFX* / P16104* / P27661* / Histone H2AX * / H2A histone family member X*  / reaction
 ENSGALG00000042491 P62801 / Histone H4   / reaction
 ENSGALG00000017159 ATM / ATM serine/threonine kinase / Q13315* / Q62388* / Serine-protein kinase ATM *  / reaction
 ENSGALG00000017211 MRE11 / double-strand break repair protein MRE11 / Mre11a* / Q61216* / P49959* / MRE11 homolog, double strand break repair nuclease*  / reaction






 

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