ENSGALG00000004508


Gallus gallus

Features
Gene ID: ENSGALG00000004508
  
Biological name :EYA2
  
Synonyms : EYA2 / Gallus gallus EYA transcriptional coactivator and phosphatase 2 (EYA2), mRNA.
  
Possible biological names infered from orthology : EYA transcriptional coactivator and phosphatase 2 / Eyes absent homolog 2 / O00167 / O08575
  
Species: Gallus gallus
  
Chr. number: 20
Strand: 1
Band:
Gene start: 5843310
Gene end: 5951540
  
Corresponding Affymetrix probe sets: Gga.1839.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000050328
Ensembl peptide - ENSGALP00000007168
NCBI entrez gene - 107054875     See in Manteia.
NCBI entrez gene - 395745     See in Manteia.
RefSeq - NM_204915
RefSeq - XM_015296717
RefSeq Peptide - NP_990246
swissprot - A0A1D5PC43
swissprot - F1NPL5
Ensembl - ENSGALG00000004508
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 eya2ENSDARG00000018984Danio rerio
 EYA2ENSG00000064655Homo sapiens
 Eya2ENSMUSG00000017897Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
EYA1 / EYA transcriptional coactivator and phosphatase 1 / P97767* / Q99502* / Eyes absent homolog 1 *ENSGALG0000004303367
EYA4 / EYA transcriptional coactivator and phosphatase 4 / O95677* / Q9Z191* / Mus musculus EYA transcriptional coactivator and phosphatase 4 (Eya4), transcript variant 2, mRNA.*ENSGALG0000003165661
EYA3 / EYA transcriptional coactivator and phosphatase 3 / P97480* / Q99504* / Eyes absent homolog 3 *ENSGALG0000000077740
EYA2* / O00167* / O08575* / Eyes absent homolog 2 * / EYA transcriptional coactivator and phosphatase 2*ENSGALG0000004252320


Protein motifs (from Interpro)
Interpro ID Name
 IPR006545  EYA domain
 IPR023214  HAD superfamily
 IPR028472  Eyes absent family
 IPR028473  Eyes absent homologue 2


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006470 protein dephosphorylation IEA
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0014706 striated muscle tissue development IEA
 biological_processGO:0016576 histone dephosphorylation IBA
 biological_processGO:0030154 cell differentiation IBA
 biological_processGO:0035335 peptidyl-tyrosine dephosphorylation IEA
 biological_processGO:0045739 positive regulation of DNA repair IBA
 biological_processGO:0048856 anatomical structure development IBA
 biological_processGO:2001240 negative regulation of extrinsic apoptotic signaling pathway in absence of ligand IBA
 cellular_componentGO:0005634 nucleus IBA
 molecular_functionGO:0004721 phosphoprotein phosphatase activity IEA
 molecular_functionGO:0004725 protein tyrosine phosphatase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000017159 ATM / ATM serine/threonine kinase / Q13315* / Q62388* / Serine-protein kinase ATM *  / reaction






 

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