ENSGALG00000007971


Gallus gallus

Features
Gene ID: ENSGALG00000007971
  
Biological name :SUMO2
  
Synonyms : Q5ZJM9 / Small ubiquitin-related modifier 2 / SUMO2
  
Possible biological names infered from orthology : P61956 / P61957 / Q6EEV6 / small ubiquitin-like modifier 2 / small ubiquitin-like modifier 4 / SUMO4
  
Species: Gallus gallus
  
Chr. number: 18
Strand: -1
Band:
Gene start: 10765476
Gene end: 10777024
  
Corresponding Affymetrix probe sets: Gga.4037.3.S1_at (Chicken Array)   GgaAffx.12508.1.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000053235
Ensembl peptide - ENSGALP00000064677
Ensembl peptide - ENSGALP00000012928
NCBI entrez gene - 770125     See in Manteia.
RefSeq - NM_001080717
RefSeq Peptide - NP_001074186
swissprot - A0A1D5PK81
swissprot - Q5ZJM9
Ensembl - ENSGALG00000007971
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Q6DHL4ENSDARG00000102741Danio rerio
 SUMO2ENSG00000188612Homo sapiens
 SUMO4ENSG00000177688Homo sapiens
 Sumo2ENSMUSG00000020738Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
SUMO3 / small ubiquitin-related modifier 3 precursor / P55854* / Q9Z172* / small ubiquitin-like modifier 3*ENSGALG0000003278374
SUMO1 / Q8QGH2 / Small ubiquitin-related modifier 1 / P63166* / P63165* / small ubiquitin-like modifier 1*ENSGALG0000000843538


Protein motifs (from Interpro)
Interpro ID Name
 IPR000626  Ubiquitin domain
 IPR022617  Rad60/SUMO-like domain
 IPR029071  Ubiquitin-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0016925 protein sumoylation IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 cellular_componentGO:0005634 nucleus IBA
 molecular_functionGO:0019789 SUMO transferase activity IEA
 molecular_functionGO:0031386 protein tag IBA


Pathways (from Reactome)
Pathway description
Vitamin D (calciferol) metabolism
SUMO is proteolytically processed
SUMOylation of DNA damage response and repair proteins
SUMOylation of transcription factors
SUMOylation of transcription cofactors
SUMOylation of SUMOylation proteins
SUMOylation of intracellular receptors
SUMOylation of chromatin organization proteins
SUMOylation of RNA binding proteins
SUMOylation of DNA replication proteins
Processing of DNA double-strand break ends
Formation of Incision Complex in GG-NER


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000002803 MTA1 / metastasis-associated protein MTA1 / Q13330* / Q8K4B0* / metastasis associated 1* / Mus musculus metastasis associated 1 (Mta1), transcript variant 2, mRNA.*  / reaction
 ENSGALG00000003072 RPA1 / Q5ZJJ2 / Replication protein A 70 kDa DNA-binding subunit / Q8VEE4* / P27694* / replication protein A1*  / reaction
 ENSGALG00000031457 TDG / thymine DNA glycosylase / P56581* / Q13569* / Mus musculus thymine DNA glycosylase (Tdg), transcript variant 3, mRNA.*  / reaction
 ENSGALG00000007971 SUMO2 / Q5ZJM9 / Small ubiquitin-related modifier 2 / SUMO4* / Q6EEV6* / P61957* / P61956* / small ubiquitin-like modifier 2* / small ubiquitin-like modifier 4*  / reaction / complex
 ENSGALG00000031796 SP3 / Q90WR8 / Transcription factor Sp3 / Q02447* / O70494* / Sp3 transcription factor*  / reaction
 ENSGALG00000009228 PARP1 / poly / P09874* / poly(ADP-ribose) polymerase 1* / poly (ADP-ribose) polymerase family, member 1*  / reaction
 ENSGALG00000001080 NR5A1 / steroidogenic factor 1 / P33242* / Q13285* / nuclear receptor subfamily 5 group A member 1*  / reaction
 ENSGALG00000034413 PIAS4 / protein inhibitor of activated STAT 4 / Q8N2W9* / Q9JM05*  / complex / reaction
 ENSGALG00000006357 XPC / XPC complex subunit, DNA damage recognition and repair factor / P51612* / Q01831* / xeroderma pigmentosum, complementation group C*  / complex
 ENSGALG00000036790 P79781 / RPS27A / Ubiquitin-40S ribosomal protein S27a Ubiquitin 40S ribosomal protein S27a / P62983* / P62979* / AL136454.1* / ribosomal protein S27a*  / complex
 ENSGALG00000007510 CETN2 / CETN1* / Q9R1K9* / P41209* / Q12798* / P41208* / centrin 2* / centrin 1*  / complex / reaction
 ENSGALG00000013365 SAFB* / SAFB2* / Q80YR5* / D3YXK2* / Q14151* / Q15424* / scaffold attachment factor B* / scaffold attachment factor B2* / Scaffold attachment factor B1 *  / reaction
 ENSGALG00000001948 SAFB* / SAFB2* / Q80YR5* / D3YXK2* / Q14151* / Q15424* / scaffold attachment factor B* / scaffold attachment factor B2* / Scaffold attachment factor B1 *  / reaction
 ENSGALG00000004288 HDAC4 / P83038 / Histone deacetylase 4 / P56524* / Q6NZM9*  / reaction
 ENSGALG00000037716 UBA52 / ubiquitin A-52 residue ribosomal protein fusion product 1 / P62984* / P62987* / Gm5239* / Gm11808* / predicted gene 11808*  / complex
 ENSGALG00000006392 RNF168 / ring finger protein 168 / Q80XJ2* / Q8IYW5* / E3 ubiquitin-protein ligase RNF168 *  / complex / reaction
 ENSGALG00000008545 SENP5 / SUMO1/sentrin specific peptidase 5 / Q6NXL6* / Q96HI0* / Sentrin-specific protease 5 *  / reaction
 ENSGALG00000008435 SUMO1 / Q8QGH2 / Small ubiquitin-related modifier 1 / P63166* / P63165* / small ubiquitin-like modifier 1*  / complex / reaction
 ENSGALG00000006428 UBE2I / P63283 / SUMO-conjugating enzyme UBC9 / P63280* / P63279* / ubiquitin conjugating enzyme E2 I*  / complex / reaction
 ENSGALG00000011976 L3MBTL2 / L3MBTL2, polycomb repressive complex 1 subunit / P59178* / Q969R5* / Lethal(3)malignant brain tumor-like protein 2 *  / reaction
 ENSGALG00000017159 ATM / ATM serine/threonine kinase / Q13315* / Q62388* / Serine-protein kinase ATM *  / complex / reaction
 ENSGALG00000016739 HERC2 / HECT and RLD domain containing E3 ubiquitin protein ligase 2 / O95714* / Q4U2R1* / E3 ubiquitin-protein ligase HERC2 *  / complex / reaction
 ENSGALG00000017211 MRE11 / double-strand break repair protein MRE11 / Mre11a* / Q61216* / P49959* / MRE11 homolog, double strand break repair nuclease*  / complex / reaction
 ENSGALG00000011254 SATB1 / SATB homeobox 1 / Q01826* / Q60611* / Mus musculus special AT-rich sequence binding protein 1 (Satb1), transcript variant 5, mRNA.*  / reaction
 ENSGALG00000015705 NSD2 / nuclear receptor binding SET domain protein 2 / O96028* / Q8BVE8* / Histone-lysine N-methyltransferase NSD2 *  / reaction / complex
 ENSGALG00000028133 UBE2V2 / Q5F3Z3 / Ubiquitin-conjugating enzyme E2 variant 2 / Q9D2M8* / Q15819* / ubiquitin conjugating enzyme E2 V2*  / reaction / complex
 ENSGALG00000006794 RAD50* / Q92878* / AC116366.3* / RAD50 double strand break repair protein*  / reaction / complex
 ENSGALG00000003922 TOP2A / DNA topoisomerase 2-alpha / P11388* / Q01320* / DNA topoisomerase II alpha*  / reaction
 ENSGALG00000026449 H2AFX* / P16104* / P27661* / Histone H2AX * / H2A histone family member X*  / complex / reaction
 ENSGALG00000023256 RNF8 / ring finger protein 8 / O76064* / Q8VC56* / Gm28043* / E3 ubiquitin-protein ligase RNF8 *  / reaction / complex
 ENSGALG00000038059 NR1H3 / nuclear receptor subfamily 1 group H member 3 / Q13133* / Q9Z0Y9* / Mus musculus nuclear receptor subfamily 1, group H, member 3 (Nr1h3), transcript variant 3, mRNA.*  / reaction
 ENSGALG00000031128 SENP2 / SUMO1/sentrin/SMT3 specific peptidase 2 / Gm7275* / Gm5407* / Gm5415* / Q91ZX6* / Q9HC62* / AF366264* / 4930444G20Rik* / cDNA sequence AF366264* / RIKEN cDNA 4930444G20 gene* / Mus ...  / reaction
 ENSGALG00000039942 CTBP1 / C-terminal-binding protein 1 / O88712* / Q13363*  / reaction
 ENSGALG00000042491 P62801 / Histone H4   / complex / reaction
 ENSGALG00000045534 PML* / P29590* / Q60953* / Protein PML * / promyelocytic leukemia*  / reaction
 ENSGALG00000045705 H2AFX* / P16104* / P27661* / Histone H2AX * / H2A histone family member X*  / reaction / complex






 

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