ENSGALG00000011976


Gallus gallus

Features
Gene ID: ENSGALG00000011976
  
Biological name :L3MBTL2
  
Synonyms : L3MBTL2 / L3MBTL2, polycomb repressive complex 1 subunit
  
Possible biological names infered from orthology : Lethal(3)malignant brain tumor-like protein 2 / P59178 / Q969R5
  
Species: Gallus gallus
  
Chr. number: 1
Strand: -1
Band:
Gene start: 49793237
Gene end: 49807832
  
Corresponding Affymetrix probe sets: Gga.16661.1.S1_s_at (Chicken Array)   Gga.19860.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000019511
NCBI entrez gene - 417999     See in Manteia.
RefSeq - NM_001006238
RefSeq - XM_015285162
RefSeq Peptide - NP_001006238
swissprot - Q5ZLC2
Ensembl - ENSGALG00000011976
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 l3mbtl2ENSDARG00000056079Danio rerio
 Q969R5ENSG00000100395Homo sapiens
 P59178ENSMUSG00000022394Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
MBTD1 / mbt domain containing 1 / Q05BQ5* / Q6P5G3* / MBT domain-containing protein 1 *ENSGALG0000000295449
SFMBT1 / Scm like with four mbt domains 1 / Q9JMD1* / Q9UHJ3* / Scm-like with four MBT domains protein 1 *ENSGALG0000000175325
SFMBT2 / Scm like with four mbt domains 2 / Q5VUG0*ENSGALG0000000927924
L3MBTL1 / L3MBTL1, histone methyl-lysine binding protein / A2A5N8* / Q9Y468* / Lethal(3)malignant brain tumor-like protein 1 *ENSGALG0000003071022
ENSGALG0000002965319
SCMH1 / Scm polycomb group protein homolog 1 / Q8K214* / Q96GD3* / Polycomb protein SCMH1 *ENSGALG0000000067213
L3MBTL3 / L3MBTL3, histone methyl-lysine binding protein / Q8BLB7* / Q96JM7* / Mus musculus L3MBTL3 histone methyl-lysine binding protein (L3mbtl3), transcript variant 3, mRNA.*ENSGALG0000003403011
SCML2 / Scm polycomb group protein like 2 / Q9UQR0*ENSGALG000000165378
SCML4 / Scm polycomb group protein like 4 / Q80VG1* / Q8N228*ENSGALG000000153093


Protein motifs (from Interpro)
Interpro ID Name
 IPR004092  Mbt repeat
 IPR012313  Zinc finger, FCS-type


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 cellular_componentGO:0005634 nucleus IEA
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0035064 methylated histone binding IEA
 molecular_functionGO:0042393 histone binding IEA


Pathways (from Reactome)
Pathway description
SUMOylation of chromatin organization proteins
Transcriptional Regulation by E2F6


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000008230 PCGF6 / polycomb group ring finger 6 / Q99NA9* / Q9BYE7* / Polycomb group RING finger protein 6 *  / complex
 ENSGALG00000037219 RNF2 / ring finger protein 2 / Q99496* / Q9CQJ4* / E3 ubiquitin-protein ligase RING2 *  / complex
 ENSGALG00000006428 UBE2I / P63283 / SUMO-conjugating enzyme UBC9 / P63280* / P63279* / ubiquitin conjugating enzyme E2 I*  / reaction
 ENSGALG00000009540 YAF2 / YY1 associated factor 2 / Q8IY57* / Q99LW6*  / complex
 ENSGALG00000007971 SUMO2 / Q5ZJM9 / Small ubiquitin-related modifier 2 / SUMO4* / Q6EEV6* / P61957* / P61956* / small ubiquitin-like modifier 2* / small ubiquitin-like modifier 4*  / reaction
 ENSGALG00000016454 E2F6 / E2F transcription factor 6 / O54917* / O75461* / Transcription factor E2F6 *  / complex / reaction
 ENSGALG00000011038 CBX3 / Q13185* / chromobox 3* / chromobox protein homolog 3 *  / complex / reaction
 ENSGALG00000016823 TFDP1* / TFDP3* / Q5H9I0* / Q08639* / Q14186* / transcription factor Dp-1* / transcription factor Dp family member 3*  / complex / reaction






 

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