ENSDARG00000056079


Danio rerio

Features
Gene ID: ENSDARG00000056079
  
Biological name :l3mbtl2
  
Synonyms : l3mbtl2 / l(3)mbt-like 2 (Drosophila)
  
Possible biological names infered from orthology : L3MBTL2, polycomb repressive complex 1 subunit / Lethal(3)malignant brain tumor-like protein 2 / P59178 / Q969R5
  
Species: Danio rerio
  
Chr. number: 12
Strand: 1
Band:
Gene start: 18970790
Gene end: 18991178
  
Corresponding Affymetrix probe sets: Dr.17271.1.A1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000127262
Ensembl peptide - ENSDARP00000127192
Ensembl peptide - ENSDARP00000134087
Ensembl peptide - ENSDARP00000072956
NCBI entrez gene - 568473     See in Manteia.
RefSeq - XM_005156155
RefSeq - XM_005156156
swissprot - F1R4V8
swissprot - U3JAC6
swissprot - U3JAJ4
ZFIN ID - ZDB-GENE-030131-8713
Ensembl - ENSDARG00000056079
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 L3MBTL2ENSGALG00000011976Gallus gallus
 Q969R5ENSG00000100395Homo sapiens
 P59178ENSMUSG00000022394Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
mbtd1 / mbt domain containing 1 / Q05BQ5* / Q6P5G3* / MBT domain-containing protein 1 *ENSDARG0000006086837
sfmbt2 / Scm like with four mbt domains 2 / Q5VUG0*ENSDARG0000004551919
l3mbtl1b / l(3)mbt-like 1b (Drosophila)ENSDARG0000007434619
SFMBT1 / Scm like with four mbt domains 1 / Q9UHJ3*ENSDARG0000010983019
l3mbtl3 / l(3)mbt-like 3 (Drosophila) / Q8BLB7* / Q96JM7* / L3MBTL3, histone methyl-lysine binding protein* / Mus musculus L3MBTL3 histone methyl-lysine binding protein (L3mbtl3), transcrip...ENSDARG0000002598317
l3mbtl1a / l(3)mbt-like 1a (Drosophila) / A2A5N8* / Q9Y468* / L3MBTL1* / Lethal(3)malignant brain tumor-like protein 1 * / L3MBTL1, histone methyl-lysine binding protein*ENSDARG0000001482814
scml2 / Scm polycomb group protein like 2 / Q9UQR0*ENSDARG0000001294912
scmh1 / Scm polycomb group protein homolog 1 / Q8K214* / Q96GD3* / Polycomb protein SCMH1 *ENSDARG000001043114
scml4 / Scm polycomb group protein like 4 / Q80VG1* / Q8N228*ENSDARG000000172663


Protein motifs (from Interpro)
Interpro ID Name
 IPR004092  Mbt repeat
 IPR006612  THAP-type zinc finger
 IPR012313  Zinc finger, FCS-type


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 cellular_componentGO:0005634 nucleus IEA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0035064 methylated histone binding IEA


Pathways (from Reactome)
Pathway description
SUMOylation of chromatin organization proteins
Transcriptional Regulation by E2F6


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000003860 cbx3a / chromobox homolog 3a (HP1 gamma homolog, Drosophila) / CBX3* / Q13185* / chromobox 3*  / complex / reaction
 ENSDARG00000008119 si:ch211-195d17.2 / E2F6* / O54917* / O75461* / E2F transcription factor 6* / Transcription factor E2F6 *  / complex / reaction
 ENSDARG00000024844 max / myc associated factor X / P61244* / Max protein*  / reaction / complex
 ENSDARG00000015966 yaf2 / YY1 associated factor 2 / Q8IY57* / Q99LW6*  / complex
 ENSDARG00000052649 Q9DDJ0 / ube2ia / ubiquitin-conjugating enzyme E2Ia / UBE2I* / P63280* / P63279* / ubiquitin conjugating enzyme E2 I*  / reaction
 ENSDARG00000102741 sumo2b / Q6DHL4 / small ubiquitin-like modifier 2b / SUMO4* / SUMO2* / Q6EEV6* / P61956* / P61957* / small ubiquitin-like modifier 4* / small ubiquitin-like modifier 2*  / reaction
 ENSDARG00000069681 pcgf6 / polycomb group ring finger 6 / Q99NA9* / Q9BYE7* / Polycomb group RING finger protein 6 *  / complex
 ENSDARG00000010381 rnf2 / Q803I4 / ring finger protein 2 / Q99496* / Q9CQJ4* / E3 ubiquitin-protein ligase RING2 *  / complex
 ENSDARG00000007438 ube2ib / Q9W6H5 / ubiquitin-conjugating enzyme E2Ib / UBE2I* / P63279* / ubiquitin conjugating enzyme E2 I*  / reaction
 ENSDARG00000019293 tfdp1a / transcription factor Dp-1, a / TFDP1* / TFDP3* / Q14186* / Q5H9I0* / Q08639* / transcription factor Dp-1* / transcription factor Dp family member 3*  / complex / reaction
 ENSDARG00000092158 cbx3b / chromobox homolog 3b / CBX3* / Q13185* / chromobox 3* / chromobox protein homolog 3 *  / complex / reaction






 

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