ENSDARG00000015966


Danio rerio

Features
Gene ID: ENSDARG00000015966
  
Biological name :yaf2
  
Synonyms : yaf2 / YY1 associated factor 2
  
Possible biological names infered from orthology : Q8IY57 / Q99LW6
  
Species: Danio rerio
  
Chr. number: 4
Strand: -1
Band:
Gene start: 13905522
Gene end: 13921206
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000074784
Ensembl peptide - ENSDARP00000112899
NCBI entrez gene - 692296     See in Manteia.
RefSeq - NM_001045268
RefSeq Peptide - NP_001038733
swissprot - Q5SP48
swissprot - Q5SP49
ZFIN ID - ZDB-GENE-041210-115
Ensembl - ENSDARG00000015966
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 YAF2ENSGALG00000009540Gallus gallus
 YAF2ENSG00000015153Homo sapiens
 Yaf2ENSMUSG00000022634Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
rybpb / RING1 and YY1 binding protein b / RYBP* / Q8CCI5* / Q8N488* / RING1 and YY1 binding protein*ENSDARG0000005345959
rybpa / RING1 and YY1 binding protein a / RYBP* / Q8CCI5* / Q8N488* / RING1 and YY1 binding protein*ENSDARG0000003777356


Protein motifs (from Interpro)
Interpro ID Name
 IPR001876  Zinc finger, RanBP2-type
 IPR033774  Yaf2/RYBP C-terminal binding motif


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0030900 forebrain development IMP
 biological_processGO:0043066 negative regulation of apoptotic process IMP
 biological_processGO:1903506 regulation of nucleic acid-templated transcription IEA
 biological_processGO:1903507 negative regulation of nucleic acid-templated transcription IEA
 molecular_functionGO:0003713 transcription coactivator activity IEA
 molecular_functionGO:0003714 transcription corepressor activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known
Transcriptional Regulation by E2F6


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000003860 cbx3a / chromobox homolog 3a (HP1 gamma homolog, Drosophila) / CBX3* / Q13185* / chromobox 3*  / reaction / complex
 ENSDARG00000008119 si:ch211-195d17.2 / E2F6* / O54917* / O75461* / E2F transcription factor 6* / Transcription factor E2F6 *  / reaction / complex
 ENSDARG00000024844 max / myc associated factor X / P61244* / Max protein*  / complex / reaction
 ENSDARG00000056079 l3mbtl2 / l(3)mbt-like 2 (Drosophila) / P59178* / Q969R5* / L3MBTL2, polycomb repressive complex 1 subunit* / Lethal(3)malignant brain tumor-like protein 2 *  / complex
 ENSDARG00000010381 rnf2 / Q803I4 / ring finger protein 2 / Q99496* / Q9CQJ4* / E3 ubiquitin-protein ligase RING2 *  / complex
 ENSDARG00000069681 pcgf6 / polycomb group ring finger 6 / Q99NA9* / Q9BYE7* / Polycomb group RING finger protein 6 *  / complex
 ENSDARG00000019293 tfdp1a / transcription factor Dp-1, a / TFDP1* / TFDP3* / Q14186* / Q5H9I0* / Q08639* / transcription factor Dp-1* / transcription factor Dp family member 3*  / complex / reaction
 ENSDARG00000092158 cbx3b / chromobox homolog 3b / CBX3* / Q13185* / chromobox 3* / chromobox protein homolog 3 *  / complex / reaction






 

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