ENSMUSG00000022634


Mus musculus

Features
Gene ID: ENSMUSG00000022634
  
Biological name :Yaf2
  
Synonyms : Q99LW6 / Yaf2 / YY1 associated factor 2
  
Possible biological names infered from orthology : Q8IY57
  
Species: Mus musculus
  
Chr. number: 15
Strand: -1
Band: E3
Gene start: 93284278
Gene end: 93336935
  
Corresponding Affymetrix probe sets: 10431726 (MoGene1.0st)   1423399_a_at (Mouse Genome 430 2.0 Array)   1429839_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000079179
Ensembl peptide - ENSMUSP00000155669
NCBI entrez gene - 67057     See in Manteia.
MGI - MGI:1914307
RefSeq - XM_006521292
RefSeq - NM_024189
RefSeq Peptide - NP_077151
swissprot - Q99LW6
Ensembl - ENSMUSG00000022634
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 yaf2ENSDARG00000015966Danio rerio
 YAF2ENSGALG00000009540Gallus gallus
 YAF2ENSG00000015153Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Rybp / Q8CCI5 / RING1 and YY1-binding protein / Q8N488*ENSMUSG0000007287265


Protein motifs (from Interpro)
Interpro ID Name
 IPR001876  Zinc finger, RanBP2-type
 IPR033774  Yaf2/RYBP C-terminal binding motif
 IPR036443  Zinc finger, RanBP2-type superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0045892 negative regulation of transcription, DNA-templated IEA
 biological_processGO:0045893 positive regulation of transcription, DNA-templated IEA
 cellular_componentGO:0005634 nucleus ISS
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005829 cytosol IEA
 molecular_functionGO:0003713 transcription coactivator activity ISS
 molecular_functionGO:0003714 transcription corepressor activity ISS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known
Transcriptional Regulation by E2F6


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000025050 Pcgf6 / Q99NA9 / Polycomb group RING finger protein 6 / Q9BYE7* / polycomb group ring finger 6*  / complex
 ENSMUSG00000022394 P59178 / L3mbtl2 / Lethal(3)malignant brain tumor-like protein 2 / Q969R5* / L3MBTL2, polycomb repressive complex 1 subunit*  / complex
 ENSMUSG00000029836 Cbx3 / chromobox protein homolog 3 / Q13185* / chromobox 3*  / complex / reaction
 ENSMUSG00000013787 Ehmt2 / Q9Z148 / Histone-lysine N-methyltransferase EHMT2 / Q96KQ7* / euchromatic histone lysine methyltransferase 2*  / complex / reaction
 ENSMUSG00000024325 Ring1 / O35730 / E3 ubiquitin-protein ligase RING1 / Q06587* / ring finger protein 1*  / complex
 ENSMUSG00000036893 Ehmt1 / Q5DW34 / Histone-lysine N-methyltransferase EHMT1 / Q9H9B1* / euchromatic histone lysine methyltransferase 1*  / complex / reaction
 ENSMUSG00000057469 E2f6 / O54917 / Transcription factor E2F6 / O75461* / E2F transcription factor 6*  / reaction / complex
 ENSMUSG00000038482 Tfdp1 / Q08639 / transcription factor Dp 1 / TFDP3* / Q14186* / Q5H9I0* / transcription factor Dp family member 3*  / reaction / complex
 ENSMUSG00000059436 Max / Max protein / P61244* / MYC associated factor X*  / complex / reaction
 ENSMUSG00000026484 Rnf2 / Q9CQJ4 / E3 ubiquitin-protein ligase RING2 / Q99496* / ring finger protein 2*  / complex
 ENSMUSG00000033943 Mga / A2AWL7 / MAX-associated protein / Q8IWI9* / MGA, MAX dimerization protein*  / complex / reaction






 

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