ENSGALG00000037219


Gallus gallus

Features
Gene ID: ENSGALG00000037219
  
Biological name :RNF2
  
Synonyms : ring finger protein 2 / RNF2
  
Possible biological names infered from orthology : E3 ubiquitin-protein ligase RING2 / Q99496 / Q9CQJ4
  
Species: Gallus gallus
  
Chr. number: 8
Strand: 1
Band:
Gene start: 8057403
Gene end: 8073540
  
Corresponding Affymetrix probe sets: Gga.17941.1.S1_at (Chicken Array)   Gga.4775.1.S1_at (Chicken Array)   Gga.6927.1.S1_at (Chicken Array)   GgaAffx.3000.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000046491
NCBI entrez gene - 424452     See in Manteia.
RefSeq - XM_015290550
RefSeq - XM_015290551
swissprot - A0A1D5P1F4
Ensembl - ENSGALG00000037219
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 rnf2ENSDARG00000010381Danio rerio
 RNF2ENSG00000121481Homo sapiens
 Rnf2ENSMUSG00000026484Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR001841  Zinc finger, RING-type
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR017907  Zinc finger, RING-type, conserved site
 IPR032443  RAWUL domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IEA
 biological_processGO:0000278 mitotic cell cycle IEA
 biological_processGO:0001702 gastrulation with mouth forming second IEA
 biological_processGO:0007281 germ cell development IEA
 biological_processGO:0009948 anterior/posterior axis specification IEA
 biological_processGO:0016574 histone ubiquitination IEA
 biological_processGO:0035518 histone H2A monoubiquitination IEA
 biological_processGO:0036353 histone H2A-K119 monoubiquitination IEA
 biological_processGO:0043433 negative regulation of DNA-binding transcription factor activity IEA
 cellular_componentGO:0000151 ubiquitin ligase complex IEA
 cellular_componentGO:0000791 euchromatin IEA
 cellular_componentGO:0000792 heterochromatin IEA
 cellular_componentGO:0001739 sex chromatin IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0016604 nuclear body IEA
 cellular_componentGO:0031519 PcG protein complex IEA
 cellular_componentGO:0035102 PRC1 complex IEA
 cellular_componentGO:0071339 MLL1 complex IEA
 molecular_functionGO:0003682 chromatin binding IEA
 molecular_functionGO:0004842 ubiquitin-protein transferase activity IEA
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0061630 ubiquitin protein ligase activity IEA
 molecular_functionGO:0071535 RING-like zinc finger domain binding IEA


Pathways (from Reactome)
Pathway description
Oxidative Stress Induced Senescence
SUMOylation of DNA damage response and repair proteins
SUMOylation of transcription cofactors
SUMOylation of chromatin organization proteins
SUMOylation of RNA binding proteins
RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known
Regulation of PTEN gene transcription
Transcriptional Regulation by E2F6


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000011976 L3MBTL2 / L3MBTL2, polycomb repressive complex 1 subunit / P59178* / Q969R5* / Lethal(3)malignant brain tumor-like protein 2 *  / complex
 ENSGALG00000016454 E2F6 / E2F transcription factor 6 / O54917* / O75461* / Transcription factor E2F6 *  / complex / reaction
 ENSGALG00000011038 CBX3 / Q13185* / chromobox 3* / chromobox protein homolog 3 *  / complex / reaction
 ENSGALG00000016823 TFDP1* / TFDP3* / Q5H9I0* / Q08639* / Q14186* / transcription factor Dp-1* / transcription factor Dp family member 3*  / reaction / complex
 ENSGALG00000008230 PCGF6 / polycomb group ring finger 6 / Q99NA9* / Q9BYE7* / Polycomb group RING finger protein 6 *  / complex
 ENSGALG00000009540 YAF2 / YY1 associated factor 2 / Q8IY57* / Q99LW6*  / complex






 

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