ENSGALG00000001080


Gallus gallus

Features
Gene ID: ENSGALG00000001080
  
Biological name :NR5A1
  
Synonyms : NR5A1 / steroidogenic factor 1
  
Possible biological names infered from orthology : nuclear receptor subfamily 5 group A member 1 / P33242 / Q13285
  
Species: Gallus gallus
  
Chr. number: 17
Strand: -1
Band:
Gene start: 9914203
Gene end: 9930043
  
Corresponding Affymetrix probe sets: Gga.571.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000001614
NCBI entrez gene - 395960     See in Manteia.
RefSeq - XM_015279334
RefSeq - NM_205077
RefSeq - XM_015279332
RefSeq - XM_015279333
RefSeq Peptide - NP_990408
swissprot - E1BXV1
Ensembl - ENSGALG00000001080
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 nr5a1aENSDARG00000103176Danio rerio
 nr5a1bENSDARG00000023362Danio rerio
 nr6a1aENSDARG00000096224Danio rerio
 NR5A1ENSG00000136931Homo sapiens
 Nr5a1ENSMUSG00000026751Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
NR5A2 / nuclear receptor subfamily 5 group A member 2 / O00482* / P45448*ENSGALG0000000218271
NR1D2 / nuclear receptor subfamily 1 group D member 2 / Q14995* / Q60674*ENSGALG0000001129123
NR6A1 / nuclear receptor subfamily 6 group A member 1 / Q15406* / Q64249*ENSGALG0000000107320
ENSGALG0000000103520
RORB / RAR related orphan receptor B / Q8R1B8* / Q92753* / Nuclear receptor ROR-beta *ENSGALG0000001515020
RORA / nuclear receptor ROR-alpha / P51448* / P35398* / RAR related orphan receptor A* / RAR-related orphan receptor alpha*ENSGALG0000000375919
RORC / RAR related orphan receptor C / P51449* / P51450* / Nuclear receptor ROR-gamma *ENSGALG0000003394118
PPARG / peroxisome proliferator activated receptor gamma / P37231*ENSGALG0000000497418
PPARD / peroxisome proliferator-activated receptor delta / P35396* / Q03181*ENSGALG0000000258818
PPARA / peroxisome proliferator-activated receptor alpha / P23204* / Q07869*ENSGALG0000004147017


Protein motifs (from Interpro)
Interpro ID Name
 IPR000536  Nuclear hormone receptor, ligand-binding domain
 IPR001628  Zinc finger, nuclear hormone receptor-type
 IPR001723  Nuclear hormone receptor
 IPR013088  Zinc finger, NHR/GATA-type
 IPR016355  Nuclear hormone receptor family 5


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001553 luteinization IEA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IEA
 biological_processGO:0007530 sex determination IEA
 biological_processGO:0008584 male gonad development IEA
 biological_processGO:0008585 female gonad development IEA
 biological_processGO:0009755 hormone-mediated signaling pathway IBA
 biological_processGO:0009888 tissue development IEA
 biological_processGO:0010259 multicellular organism aging IEA
 biological_processGO:0010628 positive regulation of gene expression IEA
 biological_processGO:0022414 reproductive process IEA
 biological_processGO:0030154 cell differentiation IEA
 biological_processGO:0030325 adrenal gland development IEA
 biological_processGO:0030522 intracellular receptor signaling pathway IEA
 biological_processGO:0042445 hormone metabolic process IEA
 biological_processGO:0043401 steroid hormone mediated signaling pathway IEA
 biological_processGO:0045893 positive regulation of transcription, DNA-templated IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 biological_processGO:0051457 maintenance of protein location in nucleus IEA
 biological_processGO:2000020 positive regulation of male gonad development IEA
 biological_processGO:2000195 negative regulation of female gonad development IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0090575 RNA polymerase II transcription factor complex IEA
 molecular_functionGO:0000976 transcription regulatory region sequence-specific DNA binding IBA
 molecular_functionGO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding IEA
 molecular_functionGO:0000980 RNA polymerase II distal enhancer sequence-specific DNA binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003682 chromatin binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IEA
 molecular_functionGO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding IEA
 molecular_functionGO:0003707 steroid hormone receptor activity IEA
 molecular_functionGO:0004879 nuclear receptor activity IEA
 molecular_functionGO:0005543 phospholipid binding IEA
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0019899 enzyme binding IEA
 molecular_functionGO:0043565 sequence-specific DNA binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Nuclear Receptor transcription pathway
SUMOylation of intracellular receptors


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000007971 SUMO2 / Q5ZJM9 / Small ubiquitin-related modifier 2 / SUMO4* / Q6EEV6* / P61957* / P61956* / small ubiquitin-like modifier 2* / small ubiquitin-like modifier 4*  / reaction
 ENSGALG00000008435 SUMO1 / Q8QGH2 / Small ubiquitin-related modifier 1 / P63166* / P63165* / small ubiquitin-like modifier 1*  / complex / reaction
 ENSGALG00000006428 UBE2I / P63283 / SUMO-conjugating enzyme UBC9 / P63280* / P63279* / ubiquitin conjugating enzyme E2 I*  / reaction






 

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