ENSGALG00000002182


Gallus gallus

Features
Gene ID: ENSGALG00000002182
  
Biological name :NR5A2
  
Synonyms : NR5A2 / nuclear receptor subfamily 5 group A member 2
  
Possible biological names infered from orthology : O00482 / P45448
  
Species: Gallus gallus
  
Chr. number: 8
Strand: -1
Band:
Gene start: 1592876
Gene end: 1687096
  
Corresponding Affymetrix probe sets: Gga.572.1.S1_at (Chicken Array)   Gga.572.1.S2_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000003413
Ensembl peptide - ENSGALP00000057283
Ensembl peptide - ENSGALP00000056574
NCBI entrez gene - 395961     See in Manteia.
RefSeq - NM_205078
RefSeq - XM_015290243
RefSeq Peptide - NP_990409
swissprot - A0A1D5PWF2
swissprot - A0A1D5PUH1
swissprot - F1NVB5
Ensembl - ENSGALG00000002182
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 nr5a2ENSDARG00000100940Danio rerio
 NR5A2ENSG00000116833Homo sapiens
 Nr5a2ENSMUSG00000026398Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
NR5A1 / steroidogenic factor 1 / P33242* / Q13285* / nuclear receptor subfamily 5 group A member 1*ENSGALG0000000108066
NR1D2 / nuclear receptor subfamily 1 group D member 2 / Q14995* / Q60674*ENSGALG0000001129124
NR6A1 / nuclear receptor subfamily 6 group A member 1 / Q15406* / Q64249*ENSGALG0000000107320
ENSGALG0000000103520
RORB / RAR related orphan receptor B / Q8R1B8* / Q92753* / Nuclear receptor ROR-beta *ENSGALG0000001515020
RORA / nuclear receptor ROR-alpha / P51448* / P35398* / RAR related orphan receptor A* / RAR-related orphan receptor alpha*ENSGALG0000000375920
PPARG / peroxisome proliferator activated receptor gamma / P37231*ENSGALG0000000497419
PPARD / peroxisome proliferator-activated receptor delta / P35396* / Q03181*ENSGALG0000000258818
PPARA / peroxisome proliferator-activated receptor alpha / P23204* / Q07869*ENSGALG0000004147018
RORC / RAR related orphan receptor C / P51449* / P51450* / Nuclear receptor ROR-gamma *ENSGALG0000003394118


Protein motifs (from Interpro)
Interpro ID Name
 IPR000536  Nuclear hormone receptor, ligand-binding domain
 IPR001628  Zinc finger, nuclear hormone receptor-type
 IPR001723  Nuclear hormone receptor
 IPR013088  Zinc finger, NHR/GATA-type
 IPR016355  Nuclear hormone receptor family 5


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006366 transcription by RNA polymerase II IEA
 biological_processGO:0008206 bile acid metabolic process IEA
 biological_processGO:0030855 epithelial cell differentiation IEA
 biological_processGO:0042127 regulation of cell proliferation IEA
 biological_processGO:0042632 cholesterol homeostasis IEA
 biological_processGO:0043401 steroid hormone mediated signaling pathway IEA
 biological_processGO:0045070 positive regulation of viral genome replication IEA
 biological_processGO:0045893 positive regulation of transcription, DNA-templated IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 biological_processGO:0061113 pancreas morphogenesis IEA
 biological_processGO:1990830 cellular response to leukemia inhibitory factor IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0090575 RNA polymerase II transcription factor complex IEA
 molecular_functionGO:0000978 RNA polymerase II proximal promoter sequence-specific DNA binding IEA
 molecular_functionGO:0000980 RNA polymerase II distal enhancer sequence-specific DNA binding IEA
 molecular_functionGO:0001077 transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003682 chromatin binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IEA
 molecular_functionGO:0003707 steroid hormone receptor activity IEA
 molecular_functionGO:0005543 phospholipid binding IEA
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0043565 sequence-specific DNA binding IEA
 molecular_functionGO:0044212 transcription regulatory region DNA binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Nuclear Receptor transcription pathway
SUMOylation of intracellular receptors
Estrogen-dependent gene expression


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr