ENSGALG00000002588


Gallus gallus

Features
Gene ID: ENSGALG00000002588
  
Biological name :PPARD
  
Synonyms : peroxisome proliferator-activated receptor delta / PPARD
  
Possible biological names infered from orthology : P35396 / Q03181
  
Species: Gallus gallus
  
Chr. number: 26
Strand: -1
Band:
Gene start: 4089638
Gene end: 4106262
  
Corresponding Affymetrix probe sets: Gga.262.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000004067
NCBI entrez gene - 395479     See in Manteia.
RefSeq - XM_015298893
RefSeq - NM_204728
RefSeq - XM_015298891
RefSeq - XM_015298892
RefSeq - XM_015298888
RefSeq - XM_015298889
RefSeq - XM_015298890
RefSeq Peptide - NP_990059
swissprot - F1NHW8
Ensembl - ENSGALG00000002588
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ppardaENSDARG00000044525Danio rerio
 ppardbENSDARG00000009473Danio rerio
 PPARDENSG00000112033Homo sapiens
 PpardENSMUSG00000002250Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
PPARA / peroxisome proliferator-activated receptor alpha / P23204* / Q07869*ENSGALG0000004147066
PPARG / peroxisome proliferator activated receptor gamma / P37231*ENSGALG0000000497458
NR1D2 / nuclear receptor subfamily 1 group D member 2 / Q14995* / Q60674*ENSGALG0000001129130
ENSGALG0000000103524
RORC / RAR related orphan receptor C / P51449* / P51450* / Nuclear receptor ROR-gamma *ENSGALG0000003394124
RORB / RAR related orphan receptor B / Q8R1B8* / Q92753* / Nuclear receptor ROR-beta *ENSGALG0000001515023
RORA / nuclear receptor ROR-alpha / P51448* / P35398* / RAR related orphan receptor A* / RAR-related orphan receptor alpha*ENSGALG0000000375923
NR5A2 / nuclear receptor subfamily 5 group A member 2 / O00482* / P45448*ENSGALG0000000218221
NR6A1 / nuclear receptor subfamily 6 group A member 1 / Q15406* / Q64249*ENSGALG0000000107319
NR5A1 / steroidogenic factor 1 / P33242* / Q13285* / nuclear receptor subfamily 5 group A member 1*ENSGALG0000000108019


Protein motifs (from Interpro)
Interpro ID Name
 IPR000536  Nuclear hormone receptor, ligand-binding domain
 IPR001628  Zinc finger, nuclear hormone receptor-type
 IPR001723  Nuclear hormone receptor
 IPR003074  Peroxisome proliferator-activated receptor
 IPR003075  Peroxisome proliferator-activated receptor, beta
 IPR013088  Zinc finger, NHR/GATA-type


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IEA
 biological_processGO:0001890 placenta development IEA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006629 lipid metabolic process IEA
 biological_processGO:0006635 fatty acid beta-oxidation IEA
 biological_processGO:0006915 apoptotic process IEA
 biological_processGO:0007566 embryo implantation IEA
 biological_processGO:0008283 cell proliferation IEA
 biological_processGO:0008284 positive regulation of cell proliferation IEA
 biological_processGO:0008366 axon ensheathment IEA
 biological_processGO:0010628 positive regulation of gene expression IEA
 biological_processGO:0014068 positive regulation of phosphatidylinositol 3-kinase signaling IEA
 biological_processGO:0014842 regulation of skeletal muscle satellite cell proliferation IEA
 biological_processGO:0015908 fatty acid transport IEA
 biological_processGO:0030154 cell differentiation IEA
 biological_processGO:0030522 intracellular receptor signaling pathway IEA
 biological_processGO:0031589 cell-substrate adhesion IEA
 biological_processGO:0042060 wound healing IEA
 biological_processGO:0042127 regulation of cell proliferation IEA
 biological_processGO:0043401 steroid hormone mediated signaling pathway IEA
 biological_processGO:0043415 positive regulation of skeletal muscle tissue regeneration IEA
 biological_processGO:0043616 keratinocyte proliferation IEA
 biological_processGO:0045598 regulation of fat cell differentiation IEA
 biological_processGO:0045662 negative regulation of myoblast differentiation IEA
 biological_processGO:0045893 positive regulation of transcription, DNA-templated IEA
 biological_processGO:0050680 negative regulation of epithelial cell proliferation IEA
 biological_processGO:0051546 keratinocyte migration IEA
 biological_processGO:0060612 adipose tissue development IEA
 biological_processGO:0071456 cellular response to hypoxia IEA
 biological_processGO:0097190 apoptotic signaling pathway IEA
 biological_processGO:1902894 negative regulation of pri-miRNA transcription by RNA polymerase II IEA
 biological_processGO:2000288 positive regulation of myoblast proliferation IEA
 cellular_componentGO:0000790 nuclear chromatin IEA
 cellular_componentGO:0005634 nucleus IEA
 molecular_functionGO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IEA
 molecular_functionGO:0003707 steroid hormone receptor activity IEA
 molecular_functionGO:0004879 nuclear receptor activity IEA
 molecular_functionGO:0008134 transcription factor binding IEA
 molecular_functionGO:0008144 drug binding IEA
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0008289 lipid binding IEA
 molecular_functionGO:0043565 sequence-specific DNA binding IEA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0046982 protein heterodimerization activity IEA
 molecular_functionGO:0070539 linoleic acid binding IEA


Pathways (from Reactome)
Pathway description
Import of palmitoyl-CoA into the mitochondrial matrix
Regulation of pyruvate dehydrogenase (PDH) complex
Nuclear Receptor transcription pathway
Signaling by Retinoic Acid


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000041344 FABP5 / fatty acid binding protein 5 / Q01469* / Q05816* / Fatty acid-binding protein, epidermal *  / complex / reaction






 

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