ENSGALG00000004974


Gallus gallus

Features
Gene ID: ENSGALG00000004974
  
Biological name :PPARG
  
Synonyms : peroxisome proliferator activated receptor gamma / PPARG
  
Possible biological names infered from orthology : P37231
  
Species: Gallus gallus
  
Chr. number: 12
Strand: 1
Band:
Gene start: 4859854
Gene end: 4880521
  
Corresponding Affymetrix probe sets: Gga.3858.1.S1_at (Chicken Array)   Gga.3858.2.S1_a_at (Chicken Array)   Gga.3858.3.S1_a_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000007962
NCBI entrez gene - 373928     See in Manteia.
RefSeq - XM_015292933
RefSeq - NM_001001460
RefSeq - XM_015292931
RefSeq - XM_015292932
RefSeq Peptide - NP_001001460
swissprot - Q9I878
Ensembl - ENSGALG00000004974
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 PPARGENSG00000132170Homo sapiens
 PpargENSMUSG00000000440Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
PPARA / peroxisome proliferator-activated receptor alpha / P23204* / Q07869*ENSGALG0000004147056
PPARD / peroxisome proliferator-activated receptor delta / P35396* / Q03181*ENSGALG0000000258854
NR1D2 / nuclear receptor subfamily 1 group D member 2 / Q14995* / Q60674*ENSGALG0000001129127
RORA / nuclear receptor ROR-alpha / P51448* / P35398* / RAR related orphan receptor A* / RAR-related orphan receptor alpha*ENSGALG0000000375924
RORC / RAR related orphan receptor C / P51449* / P51450* / Nuclear receptor ROR-gamma *ENSGALG0000003394123
ENSGALG0000000103523
RORB / RAR related orphan receptor B / Q8R1B8* / Q92753* / Nuclear receptor ROR-beta *ENSGALG0000001515021
NR5A2 / nuclear receptor subfamily 5 group A member 2 / O00482* / P45448*ENSGALG0000000218220
NR5A1 / steroidogenic factor 1 / P33242* / Q13285* / nuclear receptor subfamily 5 group A member 1*ENSGALG0000000108018
NR6A1 / nuclear receptor subfamily 6 group A member 1 / Q15406* / Q64249*ENSGALG0000000107317


Protein motifs (from Interpro)
Interpro ID Name
 IPR000536  Nuclear hormone receptor, ligand-binding domain
 IPR001628  Zinc finger, nuclear hormone receptor-type
 IPR001723  Nuclear hormone receptor
 IPR003074  Peroxisome proliferator-activated receptor
 IPR003077  Peroxisome proliferator-activated receptor gamma
 IPR013088  Zinc finger, NHR/GATA-type
 IPR022590  Peroxisome proliferator-activated receptor gamma, N-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IEA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process IEA
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0008217 regulation of blood pressure IEA
 biological_processGO:0010742 macrophage derived foam cell differentiation IEA
 biological_processGO:0010745 negative regulation of macrophage derived foam cell differentiation IEA
 biological_processGO:0010871 negative regulation of receptor biosynthetic process IEA
 biological_processGO:0010887 negative regulation of cholesterol storage IEA
 biological_processGO:0010891 negative regulation of sequestering of triglyceride IEA
 biological_processGO:0016525 negative regulation of angiogenesis IEA
 biological_processGO:0030224 monocyte differentiation IEA
 biological_processGO:0032526 response to retinoic acid IEA
 biological_processGO:0032869 cellular response to insulin stimulus IEA
 biological_processGO:0035357 peroxisome proliferator activated receptor signaling pathway IEA
 biological_processGO:0042593 glucose homeostasis IEA
 biological_processGO:0042953 lipoprotein transport IEA
 biological_processGO:0043388 positive regulation of DNA binding IEA
 biological_processGO:0043401 steroid hormone mediated signaling pathway IEA
 biological_processGO:0043537 negative regulation of blood vessel endothelial cell migration IEA
 biological_processGO:0045713 low-density lipoprotein particle receptor biosynthetic process IEA
 biological_processGO:0045893 positive regulation of transcription, DNA-templated IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 biological_processGO:0048469 cell maturation IEA
 biological_processGO:0048511 rhythmic process IEA
 biological_processGO:0048662 negative regulation of smooth muscle cell proliferation IEA
 biological_processGO:0051091 positive regulation of DNA-binding transcription factor activity IEA
 biological_processGO:0060336 negative regulation of interferon-gamma-mediated signaling pathway IEA
 biological_processGO:0060965 negative regulation of gene silencing by miRNA IEA
 biological_processGO:0061614 pri-miRNA transcription by RNA polymerase II IEA
 biological_processGO:0071404 cellular response to low-density lipoprotein particle stimulus IEA
 biological_processGO:1904706 negative regulation of vascular smooth muscle cell proliferation IEA
 biological_processGO:1905461 positive regulation of vascular associated smooth muscle cell apoptotic process IEA
 biological_processGO:1905563 negative regulation of vascular endothelial cell proliferation IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0032991 protein-containing complex IEA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IEA
 cellular_componentGO:0090575 RNA polymerase II transcription factor complex IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003690 double-stranded DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IEA
 molecular_functionGO:0003707 steroid hormone receptor activity IEA
 molecular_functionGO:0004879 nuclear receptor activity IEA
 molecular_functionGO:0008022 protein C-terminus binding IEA
 molecular_functionGO:0008134 transcription factor binding IEA
 molecular_functionGO:0008144 drug binding IEA
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0019899 enzyme binding IEA
 molecular_functionGO:0030374 nuclear receptor transcription coactivator activity IEA
 molecular_functionGO:0033613 activating transcription factor binding IEA
 molecular_functionGO:0042277 peptide binding IEA
 molecular_functionGO:0042802 identical protein binding IEA
 molecular_functionGO:0043565 sequence-specific DNA binding IEA
 molecular_functionGO:0043621 protein self-association IEA
 molecular_functionGO:0044212 transcription regulatory region DNA binding IEA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0046965 retinoid X receptor binding IEA
 molecular_functionGO:0046982 protein heterodimerization activity IEA
 molecular_functionGO:0050692 DBD domain binding IEA
 molecular_functionGO:0050693 LBD domain binding IEA
 molecular_functionGO:0051393 alpha-actinin binding IEA


Pathways (from Reactome)
Pathway description
Transcriptional regulation of white adipocyte differentiation
Nuclear Receptor transcription pathway


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr