ENSGALG00000003759


Gallus gallus

Features
Gene ID: ENSGALG00000003759
  
Biological name :RORA
  
Synonyms : nuclear receptor ROR-alpha / RORA
  
Possible biological names infered from orthology : P35398 / P51448 / RAR related orphan receptor A / RAR-related orphan receptor alpha
  
Species: Gallus gallus
  
Chr. number: 10
Strand: 1
Band:
Gene start: 4872253
Gene end: 4975286
  
Corresponding Affymetrix probe sets: GgaAffx.2351.1.S1_at (Chicken Array)   GgaAffx.2351.2.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000005957
NCBI entrez gene - 415377     See in Manteia.
RefSeq - XM_015278889
RefSeq - NM_001289887
RefSeq - XM_015278887
RefSeq - XM_015278888
RefSeq - XM_004943750
RefSeq Peptide - NP_001276816
swissprot - F1NML9
Ensembl - ENSGALG00000003759
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 roraaENSDARG00000031768Danio rerio
 RORAENSG00000069667Homo sapiens
 RoraENSMUSG00000032238Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
RORB / RAR related orphan receptor B / Q8R1B8* / Q92753* / Nuclear receptor ROR-beta *ENSGALG0000001515063
ENSGALG0000000103554
RORC / RAR related orphan receptor C / P51449* / P51450* / Nuclear receptor ROR-gamma *ENSGALG0000003394146
NR1D2 / nuclear receptor subfamily 1 group D member 2 / Q14995* / Q60674*ENSGALG0000001129129
PPARG / peroxisome proliferator activated receptor gamma / P37231*ENSGALG0000000497425
PPARA / peroxisome proliferator-activated receptor alpha / P23204* / Q07869*ENSGALG0000004147024
PPARD / peroxisome proliferator-activated receptor delta / P35396* / Q03181*ENSGALG0000000258822
NR5A2 / nuclear receptor subfamily 5 group A member 2 / O00482* / P45448*ENSGALG0000000218221
NR5A1 / steroidogenic factor 1 / P33242* / Q13285* / nuclear receptor subfamily 5 group A member 1*ENSGALG0000000108019
NR6A1 / nuclear receptor subfamily 6 group A member 1 / Q15406* / Q64249*ENSGALG0000000107318


Protein motifs (from Interpro)
Interpro ID Name
 IPR000536  Nuclear hormone receptor, ligand-binding domain
 IPR001628  Zinc finger, nuclear hormone receptor-type
 IPR001723  Nuclear hormone receptor
 IPR003079  Nuclear receptor ROR
 IPR013088  Zinc finger, NHR/GATA-type


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001525 angiogenesis IEA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006805 xenobiotic metabolic process IEA
 biological_processGO:0006809 nitric oxide biosynthetic process IEA
 biological_processGO:0008589 regulation of smoothened signaling pathway IEA
 biological_processGO:0010575 positive regulation of vascular endothelial growth factor production IEA
 biological_processGO:0010906 regulation of glucose metabolic process IEA
 biological_processGO:0019218 regulation of steroid metabolic process IEA
 biological_processGO:0021702 cerebellar Purkinje cell differentiation IEA
 biological_processGO:0021930 cerebellar granule cell precursor proliferation IEA
 biological_processGO:0030522 intracellular receptor signaling pathway IEA
 biological_processGO:0032922 circadian regulation of gene expression IEA
 biological_processGO:0036315 cellular response to sterol IEA
 biological_processGO:0042692 muscle cell differentiation IEA
 biological_processGO:0042752 regulation of circadian rhythm IEA
 biological_processGO:0042753 positive regulation of circadian rhythm IEA
 biological_processGO:0043030 regulation of macrophage activation IEA
 biological_processGO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling IEA
 biological_processGO:0043401 steroid hormone mediated signaling pathway IEA
 biological_processGO:0045599 negative regulation of fat cell differentiation IEA
 biological_processGO:0045893 positive regulation of transcription, DNA-templated IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 biological_processGO:0046068 cGMP metabolic process IEA
 biological_processGO:0050728 negative regulation of inflammatory response IEA
 biological_processGO:0060850 regulation of transcription involved in cell fate commitment IEA
 biological_processGO:0070328 triglyceride homeostasis IEA
 biological_processGO:0071347 cellular response to interleukin-1 IEA
 biological_processGO:0071356 cellular response to tumor necrosis factor IEA
 biological_processGO:0071456 cellular response to hypoxia IEA
 biological_processGO:0072539 T-helper 17 cell differentiation IEA
 cellular_componentGO:0005634 nucleus IEA
 molecular_functionGO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding IEA
 molecular_functionGO:0001046 core promoter sequence-specific DNA binding IEA
 molecular_functionGO:0001222 transcription corepressor binding IEA
 molecular_functionGO:0001223 transcription coactivator binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IEA
 molecular_functionGO:0003707 steroid hormone receptor activity IEA
 molecular_functionGO:0004879 nuclear receptor activity IEA
 molecular_functionGO:0008013 beta-catenin binding IEA
 molecular_functionGO:0008134 transcription factor binding IEA
 molecular_functionGO:0008142 oxysterol binding IEA
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0043565 sequence-specific DNA binding IEA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0098531 transcription factor activity, direct ligand regulated sequence-specific DNA binding IEA


Pathways (from Reactome)
Pathway description
Nuclear Receptor transcription pathway
SUMOylation of intracellular receptors


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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