ENSGALG00000003369


Gallus gallus

Features
Gene ID: ENSGALG00000003369
  
Biological name :KAT2A
  
Synonyms : KAT2A / lysine acetyltransferase 2A
  
Possible biological names infered from orthology : K(lysine) acetyltransferase 2A / Q92830 / Q9JHD2
  
Species: Gallus gallus
  
Chr. number: 27
Strand: -1
Band:
Gene start: 5249880
Gene end: 5255688
  
Corresponding Affymetrix probe sets: Gga.3585.1.S2_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000005317
NCBI entrez gene - 374232     See in Manteia.
RefSeq - XM_015299652
RefSeq - XM_015299653
swissprot - F1NSS9
Ensembl - ENSGALG00000003369
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 kat2aENSDARG00000104734Danio rerio
 KAT2AENSG00000108773Homo sapiens
 Kat2aENSMUSG00000020918Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ENSGALG0000001127873
BPTF / bromodomain PHD finger transcription factor / Q12830*ENSGALG0000003822225
CECR2 / cat eye syndrome critical region protein 2 / Q9BXF3* / E9Q2Z1* / Cat eye syndrome critical region * / CECR2, histone acetyl-lysine reader*ENSGALG0000001303415


Protein motifs (from Interpro)
Interpro ID Name
 IPR000182  GNAT domain
 IPR001487  Bromodomain
 IPR009464  PCAF, N-terminal
 IPR016181  Acyl-CoA N-acyltransferase
 IPR016376  Histone acetyltransferase GCN5/PCAF
 IPR018359  Bromodomain, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001701 in utero embryonic development IEA
 biological_processGO:0001756 somitogenesis IEA
 biological_processGO:0001816 cytokine production IEA
 biological_processGO:0001843 neural tube closure IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0007399 nervous system development IEA
 biological_processGO:0007616 long-term memory IEA
 biological_processGO:0008283 cell proliferation IEA
 biological_processGO:0016573 histone acetylation IEA
 biological_processGO:0016578 histone deubiquitination IEA
 biological_processGO:0018393 internal peptidyl-lysine acetylation IEA
 biological_processGO:0021537 telencephalon development IEA
 biological_processGO:0022037 metencephalon development IEA
 biological_processGO:0030901 midbrain development IEA
 biological_processGO:0031647 regulation of protein stability IEA
 biological_processGO:0035264 multicellular organism growth IEA
 biological_processGO:0035948 positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter IEA
 biological_processGO:0043966 histone H3 acetylation IEA
 biological_processGO:0043983 histone H4-K12 acetylation IEA
 biological_processGO:0044154 histone H3-K14 acetylation IEA
 biological_processGO:0045589 regulation of regulatory T cell differentiation IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 biological_processGO:0046600 negative regulation of centriole replication IEA
 biological_processGO:0048167 regulation of synaptic plasticity IEA
 biological_processGO:0050863 regulation of T cell activation IEA
 biological_processGO:0106077 histone succinylation IEA
 biological_processGO:1903146 regulation of autophagy of mitochondrion IEA
 biological_processGO:1903955 positive regulation of protein targeting to mitochondrion IEA
 cellular_componentGO:0000123 histone acetyltransferase complex IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005671 Ada2/Gcn5/Ada3 transcription activator complex IEA
 cellular_componentGO:0005813 centrosome IEA
 cellular_componentGO:0030914 STAGA complex IEA
 cellular_componentGO:0033276 transcription factor TFTC complex IEA
 cellular_componentGO:0045252 oxoglutarate dehydrogenase complex IEA
 cellular_componentGO:0072686 mitotic spindle IEA
 molecular_functionGO:0003682 chromatin binding IEA
 molecular_functionGO:0003713 transcription coactivator activity IEA
 molecular_functionGO:0004402 histone acetyltransferase activity IEA
 molecular_functionGO:0008080 N-acetyltransferase activity IEA
 molecular_functionGO:0008134 transcription factor binding IEA
 molecular_functionGO:0010484 H3 histone acetyltransferase activity IEA
 molecular_functionGO:0016407 acetyltransferase activity IEA
 molecular_functionGO:0042826 histone deacetylase binding IEA
 molecular_functionGO:0043997 histone acetyltransferase activity (H4-K12 specific) IEA
 molecular_functionGO:0061733 peptide-lysine-N-acetyltransferase activity IEA
 molecular_functionGO:0106078 histone succinyltransferase activity IEA


Pathways (from Reactome)
Pathway description
B-WICH complex positively regulates rRNA expression
Ub-specific processing proteases
RUNX3 regulates NOTCH signaling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000020078 H3F3C / histone H3.2 / H3.Y* / H3F3B* / H3F3A* / Q6NXT2* / P84243* / P84244* / Histone H3.3 * / H3 histone family member 3B* / H3 histone family member 3A* / H3 histone family member 3C* /...  / reaction
 ENSGALG00000043062 P84229 / HIST2H3D / Histone H3.2 / Q71DI3* / histone cluster 2 H3 family member d*  / reaction
 ENSGALG00000042491 P62801 / Histone H4   / reaction
 ENSGALG00000011992 EP300 / E1A binding protein p300 / B2RWS6* / Q09472* / Histone acetyltransferase p300 *  / complex






 

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