ENSGALG00000031448


Gallus gallus

Features
Gene ID: ENSGALG00000031448
  
Biological name :MAPK6
  
Synonyms : MAPK6 / Mitogen-activated protein kinase 6 / Q5F3W3
  
Possible biological names infered from orthology : Q16659 / Q61532
  
Species: Gallus gallus
  
Chr. number: 10
Strand: -1
Band:
Gene start: 8912085
Gene end: 8940372
  
Corresponding Affymetrix probe sets: Gga.3411.1.S1_at (Chicken Array)   Gga.3411.2.S1_at (Chicken Array)   Gga.3411.3.S1_a_at (Chicken Array)   GgaAffx.26288.1.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000057521
NCBI entrez gene - 415419     See in Manteia.
RefSeq - XM_015291914
RefSeq - NM_001030549
RefSeq - XM_015291911
RefSeq - XM_015291913
RefSeq - XM_015291905
RefSeq - XM_015291906
RefSeq - XM_015291907
RefSeq - XM_015291908
RefSeq - XM_015291909
RefSeq - XM_015291910
RefSeq Peptide - NP_001025720
swissprot - Q5F3W3
Ensembl - ENSGALG00000031448
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 mapk6ENSDARG00000032103Danio rerio
 MAPK6ENSG00000069956Homo sapiens
 Mapk6ENSMUSG00000042688Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
MAPK1 / mitogen-activated protein kinase 1 / P28482* / P63085* / Mus musculus mitogen-activated protein kinase 1 (Mapk1), transcript variant 3, mRNA.*ENSGALG0000000150121
MAPK15 / mitogen-activated protein kinase 15 / Q80Y86* / Q8TD08*ENSGALG0000002927919
NLK / nemo like kinase / O54949* / Q9UBE8* / Serine/threonine-protein kinase NLK *ENSGALG0000000569917


Protein motifs (from Interpro)
Interpro ID Name
 IPR000719  Protein kinase domain
 IPR008271  Serine/threonine-protein kinase, active site
 IPR008350  Mitogen-activated protein (MAP) kinase, ERK3/4
 IPR011009  Protein kinase-like domain superfamily
 IPR017441  Protein kinase, ATP binding site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000165 MAPK cascade IEA
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0007049 cell cycle IEA
 biological_processGO:0010468 regulation of gene expression IBA
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0060999 positive regulation of dendritic spine development IEA
 biological_processGO:0071310 cellular response to organic substance IBA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0032156 septin cytoskeleton IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004674 protein serine/threonine kinase activity IEA
 molecular_functionGO:0004707 MAP kinase activity IBA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0019901 protein kinase binding IEA
 molecular_functionGO:0046982 protein heterodimerization activity IEA


Pathways (from Reactome)
Pathway description
MAPK6/MAPK4 signaling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000000681 PAK1 / p21 (RAC1) activated kinase 1 / Q13153* / Mus musculus p21 protein (Cdc42/Rac)-activated kinase 1 (Pak1), transcript variant 3, mRNA.*  / reaction
 ENSGALG00000004743 MAPKAPK5 / mitogen-activated protein kinase-activated protein kinase 5 / Q8IW41* / O54992* / Gm42878* / MAP kinase-activated protein kinase 5 *  / complex / reaction
 ENSGALG00000003085 CDK1 / cyclin-dependent kinase 1 / P06493* / P11440*  / reaction
 ENSGALG00000003485 CCND3 / cyclin D3 / P30281* / P30282* / G1/S-specific cyclin-D3 *  / complex / reaction
 ENSGALG00000008058 PAK3 / p21 (RAC1) activated kinase 3 / O75914* / Q61036* / Serine/threonine-protein kinase PAK 3 *  / reaction
 ENSGALG00000006426 PAK2 / p21 (RAC1) activated kinase 2 / Q13177* / Q8CIN4* / Serine/threonine-protein kinase PAK 2 PAK-2p27 PAK-2p34*  / reaction
 ENSGALG00000012627 CDC14B / Gallus gallus cell division cycle 14B (CDC14B), mRNA. / O60729* / Q6PFY9* / cell division cycle 14B* / Dual specificity protein phosphatase CDC14B *  / reaction / complex
 ENSGALG00000010551 CDC42EP3 / CDC42 effector protein 3 / Q9CQC5* / Q9UKI2*  / reaction
 ENSGALG00000004570 NCOA3 / nuclear receptor coactivator 3 / Q9Y6Q9*  / reaction






 

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