ENSMUSG00000016559


Mus musculus

Features
Gene ID: ENSMUSG00000016559
  
Biological name :H3f3b
  
Synonyms : H3f3b / Histone H3.3 / P84244
  
Possible biological names infered from orthology :
  
Species: Mus musculus
  
Chr. number: 11
Strand: -1
Band: E2
Gene start: 116021912
Gene end: 116027962
  
Corresponding Affymetrix probe sets: 10393058 (MoGene1.0st)   10500896 (MoGene1.0st)   1420376_a_at (Mouse Genome 430 2.0 Array)   1430357_at (Mouse Genome 430 2.0 Array)   1455725_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000016703
Ensembl peptide - ENSMUSP00000102062
NCBI entrez gene - 15081     See in Manteia.
MGI - MGI:1101768
RefSeq - XM_006532248
RefSeq - NM_008211
RefSeq Peptide - NP_032237
swissprot - P84244
Ensembl - ENSMUSG00000016559
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 h3f3cENSDARG00000033009Danio rerio
 H3F3CENSGALG00000020078Gallus gallus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
H3f3a / P84244 / Histone H3.3 / P84243* / H3 histone family member 3A*ENSMUSG00000060743100
P84228 / Hist2h3c2 / Histone H3.2 / Q71DI3* / HIST2H3D* / histone cluster 2 H3 family member d*ENSMUSG0000008105897
P84228 / Hist2h3c1 / Histone H3.2 ENSMUSG0000009376997
P84228 / Hist2h3b / Histone H3.2 / Q71DI3* / HIST2H3A* / histone cluster 2 H3 family member a*ENSMUSG0000007440397
P84228 / Hist1h3e / Histone H3.2 ENSMUSG0000006927397
P84228 / Hist1h3c / Histone H3.2 / Q71DI3* / HIST2H3D* / histone cluster 2 H3 family member d*ENSMUSG0000006931097
P84228 / Hist1h3f / Histone H3.2 ENSMUSG0000010021097
P84228 / Hist1h3d / Histone H3.2 ENSMUSG0000009958397
P84228 / Hist1h3b / Histone H3.2 ENSMUSG0000006926797
P68433 / Hist1h3i / Histone H3.1 ENSMUSG0000010197296
P68433 / Hist1h3a / Histone H3.1 / P68431* / HIST1H3F* / histone cluster 1 H3 family member f*ENSMUSG0000006926596
P68433 / Hist1h3h / Histone H3.1 / P68431* / HIST1H3B* / histone cluster 1 H3 family member b*ENSMUSG0000010135596
P68433 / Hist1h3g / Histone H3.1 ENSMUSG0000009951796
C0HKE2 / C0HKE3 / C0HKE4 / C0HKE5 / C0HKE6 / C0HKE7 / C0HKE8 / C0HKE9 / C0HKE1 / Hist1h2ap / Histone H2A type 1-B / P04908* / HIST1H2AE* / histone cluster 1 H2A family member e*ENSMUSG0000009477720
C0HKE2 / C0HKE3 / C0HKE4 / C0HKE5 / C0HKE6 / C0HKE7 / C0HKE8 / C0HKE9 / C0HKE1 / Hist1h2ao / Histone H2A type 1-B / P04908* / HIST1H2AE* / histone cluster 1 H2A family member e*ENSMUSG0000009424820
Q8CGP6 / Hist1h2ah / Histone H2A type 1-H / P04908* / HIST1H2AE* / histone cluster 1 H2A family member e*ENSMUSG0000006930220
C0HKE2 / C0HKE3 / C0HKE4 / C0HKE5 / C0HKE6 / C0HKE7 / C0HKE8 / C0HKE9 / C0HKE1 / Hist1h2ag / Histone H2A type 1-B ENSMUSG0000006930120
C0HKE2 / C0HKE3 / C0HKE4 / C0HKE5 / C0HKE6 / C0HKE7 / C0HKE8 / C0HKE9 / C0HKE1 / Hist1h2ai / Histone H2A type 1-B ENSMUSG0000007151620
C0HKE2 / C0HKE3 / C0HKE4 / C0HKE5 / C0HKE6 / C0HKE7 / C0HKE8 / C0HKE9 / C0HKE1 / Hist1h2ae / Histone H2A type 1-B ENSMUSG0000006927220
C0HKE2 / C0HKE3 / C0HKE4 / C0HKE5 / C0HKE6 / C0HKE7 / C0HKE8 / C0HKE9 / C0HKE1 / Hist1h2ad / Histone H2A type 1-B ENSMUSG0000007147820


Protein motifs (from Interpro)
Interpro ID Name
 IPR000164  Histone H3/CENP-A
 IPR007125  Histone H2A/H2B/H3
 IPR009072  Histone-fold


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000183 chromatin silencing at rDNA TAS
 biological_processGO:0001649 osteoblast differentiation IGI
 biological_processGO:0006334 nucleosome assembly IBA
 biological_processGO:0006997 nucleus organization IMP
 biological_processGO:0007283 spermatogenesis IMP
 biological_processGO:0007286 spermatid development IMP
 biological_processGO:0007338 single fertilization IMP
 biological_processGO:0007566 embryo implantation IMP
 biological_processGO:0008283 cell proliferation IGI
 biological_processGO:0008584 male gonad development IMP
 biological_processGO:0031508 pericentric heterochromatin assembly IGI
 biological_processGO:0031509 telomeric heterochromatin assembly IGI
 biological_processGO:0035264 multicellular organism growth IMP
 biological_processGO:0042692 muscle cell differentiation IGI
 biological_processGO:0048477 oogenesis IGI
 biological_processGO:0090230 regulation of centromere complex assembly IMP
 biological_processGO:1902340 negative regulation of chromosome condensation IGI
 cellular_componentGO:0000228 nuclear chromosome ISO
 cellular_componentGO:0000784 nuclear chromosome, telomeric region ISO
 cellular_componentGO:0000786 nucleosome ISO
 cellular_componentGO:0000788 nuclear nucleosome ISO
 cellular_componentGO:0001740 Barr body IDA
 cellular_componentGO:0005634 nucleus ISO
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005694 chromosome IEA
 molecular_functionGO:0000979 RNA polymerase II core promoter sequence-specific DNA binding ISO
 molecular_functionGO:0000980 RNA polymerase II distal enhancer sequence-specific DNA binding ISO
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0031492 nucleosomal DNA binding ISO
 molecular_functionGO:0046982 protein heterodimerization activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001265 reduced body size "smaller than average body weight, height and/or length of an organism compared to controls" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:23170]
Show

Allelic Composition: H3f3atm1.2Mnn/H3f3atm1.2Mnn
Genetic Background: involves: 129S1/Sv * 129S1/SvImJ * 129S4/SvJaeSor

 MP:0001923 reduced female fertility "reduced ability of female to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60409]
Show

Allelic Composition: H3f3btm1.1Psk/H3f3btm1.1Psk
Genetic Background: involves: C57BL/6N * FVB/N

 MP:0001925 male infertility "inability of male to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60409]
Show

Allelic Composition: H3f3atm1.2Mnn/H3f3atm1.2Mnn
Genetic Background: involves: 129S1/Sv * 129S1/SvImJ * 129S4/SvJaeSor

Allelic Composition: H3f3btm1.1Psk/H3f3btm1.1Psk
Genetic Background: involves: C57BL/6N * FVB/N

 MP:0002169 no phenotype detected "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Tbx1tm2Bem/Tbx1tm2Bem
Genetic Background: involves: 129/Sv * C57BL/6J * SJL

Allelic Composition: H3f3btm1Psk/H3f3btm1Psk
Genetic Background: involves: C57BL/6N

 MP:0003077 abnormal cell cycle "failure to progress or abnormal progression through the stages of of the cell cycle" [smb:Susan M. Bello, Mouse Genome Informatics Curator, J:91266]
Show

Allelic Composition: H3f3btm1.1Psk/H3f3btm1.1Psk
Genetic Background: involves: C57BL/6N * FVB/N

 MP:0003111 abnormal nucleus morphology "abnormalities in the nucleus and/or its surrounding membrane" [J:91473, smb:Susan M. Bello, Mouse Genome Informatics Curator]
Show

Allelic Composition: H3f3btm1.1Psk/H3f3btm1.1Psk
Genetic Background: involves: C57BL/6N * FVB/N

 MP:0003702 abnormal chromosome morphology "anomalies in the structure of the compact, intertwined molecules of DNA found in the nucleus which carry genetic information " [hdene:Howard Dene , Mouse Genome Informatics Curator]
Show

Allelic Composition: H3f3btm1.1Psk/H3f3btm1.1Psk
Genetic Background: involves: C57BL/6N * FVB/N

 MP:0003984 embryonic growth retardation "slow or limited development before birth" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: H3f3btm1.1Psk/H3f3btm1.1Psk
Genetic Background: involves: C57BL/6N * FVB/N

 MP:0004025 polyploidy "more than two chromosome sets are present" [llw2:Linda Washburn , Mouse Genome Informatics Curator]
Show

Allelic Composition: H3f3btm1.1Psk/H3f3btm1.1Psk
Genetic Background: involves: C57BL/6N * FVB/N

 MP:0008279 arrest of spermiogenesis "block in the process by which a spermatid transforms into a functional spermatozoon" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition", MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: H3f3atm1.2Mnn/H3f3atm1.2Mnn
Genetic Background: involves: 129S1/Sv * 129S1/SvImJ * 129S4/SvJaeSor

 MP:0010831 partial lethality "the appearance of lower than Mendelian ratios of offspring of a given genotype due to death of some, but not all of the organisms" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: H3f3btm1.1Psk/H3f3btm1.1Psk
Genetic Background: involves: C57BL/6N * FVB/N

Allelic Composition: H3f3btm1.1Psk/H3f3b+
Genetic Background: involves: C57BL/6N * FVB/N

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr