ENSDARG00000045636


Danio rerio

Features
Gene ID: ENSDARG00000045636
  
Biological name :rbl2
  
Synonyms : rbl2 / retinoblastoma-like 2 (p130)
  
Possible biological names infered from orthology : Q08999 / Q64700 / RB transcriptional corepressor like 2 / Retinoblastoma-like protein 2
  
Species: Danio rerio
  
Chr. number: 25
Strand: -1
Band:
Gene start: 36010815
Gene end: 36044583
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000067923
Ensembl peptide - ENSDARP00000148064
Ensembl peptide - ENSDARP00000155321
NCBI entrez gene - 100331892     See in Manteia.
swissprot - E7FDM3
ZFIN ID - ZDB-GENE-061109-2
Ensembl - ENSDARG00000045636
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 RBL2ENSGALG00000003663Gallus gallus
 RBL2ENSG00000103479Homo sapiens
 Rbl2ENSMUSG00000031666Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
rbl1 / retinoblastoma-like 1 (p107) / P28749* / RB transcriptional corepressor like 1*ENSDARG0000000814147
rb1 / retinoblastoma 1 / P13405* / P06400* / RB transcriptional corepressor 1* / Retinoblastoma-associated protein *ENSDARG0000000678221


Protein motifs (from Interpro)
Interpro ID Name
 IPR002719  Retinoblastoma-associated protein, B-box
 IPR002720  Retinoblastoma-associated protein, A-box
 IPR013763  Cyclin-like
 IPR015030  Retinoblastoma-associated protein, C-terminal
 IPR024599  Retinoblastoma-associated protein, N-terminal
 IPR028308  Retinoblastoma-like protein 2
 IPR028309  Retinoblastoma protein family


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IEA
 biological_processGO:0007049 cell cycle IEA
 biological_processGO:0051726 regulation of cell cycle IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005667 transcription factor complex IEA


Pathways (from Reactome)
Pathway description
G0 and Early G1
Cyclin D associated events in G1


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000029018 cdkn1ba / cyclin-dependent kinase inhibitor 1Ba / CDKN1B* / P46414* / P46527* / cyclin dependent kinase inhibitor 1B*  / reaction
 ENSDARG00000026577 cdk2 / cyclin-dependent kinase 2 / P24941* / P97377*  / complex / reaction
 ENSDARG00000003151 skp1 / S-phase kinase-associated protein 1 / Skp1a* / P63208* / Q9WTX5* / AC104109.3* / S-phase kinase-associated protein 1A*  / reaction / complex
 ENSDARG00000019239 cul1a / cullin 1a / CUL1* / Q13616* / Q9WTX6* / cullin 1* / Mus musculus cullin 1 (Cul1), transcript variant 3, mRNA.*  / reaction / complex
 ENSDARG00000004937 skp2 / S-phase kinase-associated protein 2, E3 ubiquitin protein ligase / Q9Z0Z3* / Q13309* / S-phase kinase associated protein 2* / S-phase kinase-associated protein 2 (p45)*  / complex / reaction
 ENSDARG00000007971 cks1b / CDC28 protein kinase regulatory subunit 1B / P61024* / P61025* / Cks1brt* / CDC28 protein kinase 1b, retrogene* / Cyclin-dependent kinases regulatory subunit 1 *  / complex / reaction
 ENSDARG00000015427 hdac1 / histone deacetylase 1 / O09106* / Q13547* / Gm10093*  / complex / reaction
 ENSDARG00000054271 cdkn1bb / cyclin-dependent kinase inhibitor 1Bb / CDKN1B* / P46414* / P46527* / cyclin dependent kinase inhibitor 1B*  / reaction
 ENSDARG00000019293 tfdp1a / transcription factor Dp-1, a / TFDP1* / TFDP3* / Q14186* / Q5H9I0* / Q08639* / transcription factor Dp-1* / transcription factor Dp family member 3*  / complex
 ENSDARG00000038812 e2f5 / E2F transcription factor 5 / Q15329* / Q61502* / Transcription factor E2F5 *  / complex
 ENSDARG00000076554 cdkn1a / cyclin-dependent kinase inhibitor 1A / P38936* / P39689* / Cyclin-dependent kinase inhibitor 1 *  / reaction
 ENSDARG00000101578 e2f4 / E2F transcription factor 4 / Q16254*  / complex
 ENSDARG00000101637 ccnd1 / Q90459 / cyclin D1 / P24385* / P25322* / G1/S-specific cyclin-D1 *  / reaction






 

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