ENSGALG00000003396


Gallus gallus

Features
Gene ID: ENSGALG00000003396
  
Biological name :NFATC3
  
Synonyms : NFATC3 / nuclear factor of activated T cells 3
  
Possible biological names infered from orthology : nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 3 / Q12968
  
Species: Gallus gallus
  
Chr. number: 11
Strand: -1
Band:
Gene start: 3421759
Gene end: 3524368
  
Corresponding Affymetrix probe sets: Gga.19337.1.S1_s_at (Chicken Array)   Gga.6313.1.S1_at (Chicken Array)   Gga.6313.1.S1_s_at (Chicken Array)   GgaAffx.25841.1.S1_at (Chicken Array)   GgaAffx.25841.2.S1_s_at (Chicken Array)   GgaAffx.25847.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000005357
Ensembl peptide - ENSGALP00000005378
Ensembl peptide - ENSGALP00000064651
Ensembl peptide - ENSGALP00000064483
Ensembl peptide - ENSGALP00000064100
Ensembl peptide - ENSGALP00000061019
Ensembl peptide - ENSGALP00000056870
Ensembl peptide - ENSGALP00000049128
Ensembl peptide - ENSGALP00000045412
NCBI entrez gene - 415711     See in Manteia.
NCBI entrez gene - 415712     See in Manteia.
RefSeq - XM_004944165
RefSeq - XM_015292362
RefSeq - XM_015292363
RefSeq - XM_015292364
RefSeq - XM_414079
swissprot - A0A1D5P8S9
swissprot - E1C4F6
swissprot - F1NSQ9
swissprot - A0A1D5NYF4
swissprot - A0A1L1S041
swissprot - A0A1L1RZ05
swissprot - A0A1L1RQF0
swissprot - A0A1D5PVA8
Ensembl - ENSGALG00000003396
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 nfatc3aENSDARG00000076297Danio rerio
 NFATC3ENSG00000072736Homo sapiens
 Nfatc3ENSMUSG00000031902Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
NFATC1 / nuclear factor of activated T cells 1 / O95644* / nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 1*ENSGALG0000004253435
NFATC2 / nuclear factor of activated T cells 2 / Q13469* / Q60591* / nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 2*ENSGALG0000000796327
NFAT5 / nuclear factor of activated T-cells 5 / O94916* / Q9WV30*ENSGALG0000003930022


Protein motifs (from Interpro)
Interpro ID Name
 IPR001269  tRNA-dihydrouridine synthase
 IPR002909  IPT domain
 IPR008366  Nuclear factor of activated T cells (NFAT)
 IPR008967  p53-like transcription factor, DNA-binding
 IPR011539  Rel homology domain (RHD), DNA-binding domain
 IPR013783  Immunoglobulin-like fold
 IPR013785  Aldolase-type TIM barrel
 IPR014720  Double-stranded RNA-binding domain
 IPR014756  Immunoglobulin E-set
 IPR018517  tRNA-dihydrouridine synthase, conserved site
 IPR032397  Rel homology dimerisation domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002943 tRNA dihydrouridine synthesis IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0008033 tRNA processing IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 biological_processGO:0055114 oxidation-reduction process IEA
 biological_processGO:1902894 negative regulation of pri-miRNA transcription by RNA polymerase II IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IEA
 molecular_functionGO:0000978 RNA polymerase II proximal promoter sequence-specific DNA binding IEA
 molecular_functionGO:0001077 transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding IEA
 molecular_functionGO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IEA
 molecular_functionGO:0003723 RNA binding IEA
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0017150 tRNA dihydrouridine synthase activity IEA
 molecular_functionGO:0050660 flavin adenine dinucleotide binding IEA


Pathways (from Reactome)
Pathway description
FCERI mediated Ca+2 mobilization
CLEC7A (Dectin-1) induces NFAT activation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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