ENSGALG00000042534


Gallus gallus

Features
Gene ID: ENSGALG00000042534
  
Biological name :NFATC1
  
Synonyms : NFATC1 / nuclear factor of activated T cells 1
  
Possible biological names infered from orthology : nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 1 / O95644
  
Species: Gallus gallus
  
Chr. number: 2
Strand: -1
Band:
Gene start: 56746642
Gene end: 56868269
  
Corresponding Affymetrix probe sets: GgaAffx.8017.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000047254
Ensembl peptide - ENSGALP00000054403
Ensembl peptide - ENSGALP00000052456
NCBI entrez gene - 420815     See in Manteia.
RefSeq - XM_015275941
RefSeq - XM_015275938
RefSeq - XM_015275939
RefSeq - XM_015275940
RefSeq - XM_004935096
RefSeq - XM_015275936
RefSeq - XM_015275937
swissprot - A0A1D5PNG2
swissprot - A0A1D5PI24
swissprot - A0A1D5P3J9
Ensembl - ENSGALG00000042534
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 nfatc1ENSDARG00000036168Danio rerio
 NFATC1ENSG00000131196Homo sapiens
 Nfatc1ENSMUSG00000033016Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
NFATC3 / nuclear factor of activated T cells 3 / Q12968* / nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 3*ENSGALG0000000339641
NFATC2 / nuclear factor of activated T cells 2 / Q13469* / Q60591* / nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 2*ENSGALG0000000796337
NFAT5 / nuclear factor of activated T-cells 5 / O94916* / Q9WV30*ENSGALG0000003930024


Protein motifs (from Interpro)
Interpro ID Name
 IPR002909  IPT domain
 IPR008366  Nuclear factor of activated T cells (NFAT)
 IPR008967  p53-like transcription factor, DNA-binding
 IPR011539  Rel homology domain (RHD), DNA-binding domain
 IPR013783  Immunoglobulin-like fold
 IPR014756  Immunoglobulin E-set
 IPR015647  Nuclear factor of activated T-cells 1
 IPR032397  Rel homology dimerisation domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0030178 negative regulation of Wnt signaling pathway IMP
 biological_processGO:0033173 calcineurin-NFAT signaling cascade IEA
 biological_processGO:0035556 intracellular signal transduction IEA
 biological_processGO:0045893 positive regulation of transcription, DNA-templated IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 biological_processGO:0048699 generation of neurons NAS
 cellular_componentGO:0000790 nuclear chromatin IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0016604 nuclear body IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IEA


Pathways (from Reactome)
Pathway description
FCERI mediated Ca+2 mobilization
Ca2+ pathway
CLEC7A (Dectin-1) induces NFAT activation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000005243 PPP3CB / Gallus gallus protein phosphatase 3 catalytic subunit beta (PPP3CB), mRNA. / P48453* / P16298* / protein phosphatase 3 catalytic subunit beta* / protein phosphatase 3, catalytic su...  / complex
 ENSGALG00000010023 CALM2 / P62149 / Calmodulin / Calm3* / CALM1* / P0DP23* / P0DP26* / P0DP27* / P0DP28* / calmodulin 1*  / complex
 ENSGALG00000039498 PPP3CA / protein phosphatase 3 catalytic subunit alpha / P63328* / Q08209* / protein phosphatase 3, catalytic subunit, alpha isoform*  / complex






 

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