ENSGALG00000005243


Gallus gallus

Features
Gene ID: ENSGALG00000005243
  
Biological name :PPP3CB
  
Synonyms : Gallus gallus protein phosphatase 3 catalytic subunit beta (PPP3CB), mRNA. / PPP3CB
  
Possible biological names infered from orthology : P16298 / P48453 / protein phosphatase 3 catalytic subunit beta / protein phosphatase 3, catalytic subunit, beta isoform
  
Species: Gallus gallus
  
Chr. number: 6
Strand: 1
Band:
Gene start: 16138394
Gene end: 16197822
  
Corresponding Affymetrix probe sets: Gga.9015.1.S1_at (Chicken Array)   GgaAffx.12859.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000039533
Ensembl peptide - ENSGALP00000008411
NCBI entrez gene - 378890     See in Manteia.
RefSeq - NM_001030340
RefSeq Peptide - NP_001025511
swissprot - Q5ZIM8
swissprot - E1C2T7
Ensembl - ENSGALG00000005243
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 P16298ENSG00000107758Homo sapiens
 P48453ENSMUSG00000021816Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
PPP3CA / protein phosphatase 3 catalytic subunit alpha / P63328* / Q08209* / protein phosphatase 3, catalytic subunit, alpha isoform*ENSGALG0000003949880


Protein motifs (from Interpro)
Interpro ID Name
 IPR004843  Calcineurin-like phosphoesterase domain, ApaH type
 IPR006186  Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase
 IPR029052  Metallo-dependent phosphatase-like


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001915 negative regulation of T cell mediated cytotoxicity IEA
 biological_processGO:0001946 lymphangiogenesis IEA
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0006470 protein dephosphorylation IEA
 biological_processGO:0007507 heart development IEA
 biological_processGO:0010468 regulation of gene expression IEA
 biological_processGO:0017156 calcium ion regulated exocytosis IEA
 biological_processGO:0030217 T cell differentiation IEA
 biological_processGO:0031987 locomotion involved in locomotory behavior IEA
 biological_processGO:0033173 calcineurin-NFAT signaling cascade IEA
 biological_processGO:0034097 response to cytokine IEA
 biological_processGO:0035176 social behavior IEA
 biological_processGO:0035690 cellular response to drug IEA
 biological_processGO:0035774 positive regulation of insulin secretion involved in cellular response to glucose stimulus IEA
 biological_processGO:0043029 T cell homeostasis IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005955 calcineurin complex IEA
 cellular_componentGO:0030018 Z disc IEA
 cellular_componentGO:0030315 T-tubule IEA
 cellular_componentGO:0030424 axon IDA
 cellular_componentGO:0043204 perikaryon IDA
 molecular_functionGO:0004721 phosphoprotein phosphatase activity IEA
 molecular_functionGO:0004722 protein serine/threonine phosphatase activity IEA
 molecular_functionGO:0005509 calcium ion binding IEA
 molecular_functionGO:0005516 calmodulin binding IEA
 molecular_functionGO:0008144 drug binding IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0019899 enzyme binding IEA
 molecular_functionGO:0030346 protein phosphatase 2B binding IEA
 molecular_functionGO:0033192 calmodulin-dependent protein phosphatase activity IEA
 molecular_functionGO:0046983 protein dimerization activity IEA


Pathways (from Reactome)
Pathway description
FCERI mediated Ca+2 mobilization
Ca2+ pathway
CLEC7A (Dectin-1) induces NFAT activation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000042534 NFATC1 / nuclear factor of activated T cells 1 / O95644* / nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 1*  / complex
 ENSGALG00000007963 NFATC2 / nuclear factor of activated T cells 2 / Q13469* / Q60591* / nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 2*  / complex
 ENSGALG00000010023 CALM2 / P62149 / Calmodulin / Calm3* / CALM1* / P0DP23* / P0DP26* / P0DP27* / P0DP28* / calmodulin 1*  / complex






 

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