ENSGALG00000004375


Gallus gallus

Features
Gene ID: ENSGALG00000004375
  
Biological name :VPS35
  
Synonyms : vacuolar protein sorting-associated protein 35 / VPS35
  
Possible biological names infered from orthology : Q96QK1 / Q9EQH3 / VPS35, retromer complex component
  
Species: Gallus gallus
  
Chr. number: 11
Strand: 1
Band:
Gene start: 7949456
Gene end: 7976331
  
Corresponding Affymetrix probe sets: GgaAffx.11986.1.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000063341
Ensembl peptide - ENSGALP00000006965
NCBI entrez gene - 415750     See in Manteia.
RefSeq - NM_001005842
RefSeq Peptide - NP_001005842
swissprot - F1NVF0
swissprot - A0A1L1RWX8
Ensembl - ENSGALG00000004375
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 vps35ENSDARG00000008224Danio rerio
 VPS35ENSG00000069329Homo sapiens
 Vps35ENSMUSG00000031696Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR005378  Vacuolar protein sorting-associated protein 35
 IPR016024  Armadillo-type fold


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006886 intracellular protein transport IBA
 biological_processGO:0007040 lysosome organization IEA
 biological_processGO:0010628 positive regulation of gene expression IEA
 biological_processGO:0010629 negative regulation of gene expression IEA
 biological_processGO:0010821 regulation of mitochondrion organization IEA
 biological_processGO:0015031 protein transport IEA
 biological_processGO:0031647 regulation of protein stability IEA
 biological_processGO:0031648 protein destabilization IEA
 biological_processGO:0032268 regulation of cellular protein metabolic process IEA
 biological_processGO:0032463 negative regulation of protein homooligomerization IEA
 biological_processGO:0033365 protein localization to organelle IEA
 biological_processGO:0042147 retrograde transport, endosome to Golgi IEA
 biological_processGO:0043653 mitochondrial fragmentation involved in apoptotic process IEA
 biological_processGO:0045056 transcytosis IEA
 biological_processGO:0050728 negative regulation of inflammatory response IEA
 biological_processGO:0050882 voluntary musculoskeletal movement IEA
 biological_processGO:0060161 positive regulation of dopamine receptor signaling pathway IEA
 biological_processGO:0060548 negative regulation of cell death IEA
 biological_processGO:0061357 positive regulation of Wnt protein secretion IEA
 biological_processGO:0090141 positive regulation of mitochondrial fission IEA
 biological_processGO:0090263 positive regulation of canonical Wnt signaling pathway IEA
 biological_processGO:0090326 positive regulation of locomotion involved in locomotory behavior IEA
 biological_processGO:0099074 mitochondrion to lysosome transport IEA
 biological_processGO:0099639 neurotransmitter receptor transport, endosome to plasma membrane IEA
 biological_processGO:1901215 negative regulation of neuron death IEA
 biological_processGO:1902823 negative regulation of late endosome to lysosome transport IEA
 biological_processGO:1902950 regulation of dendritic spine maintenance IEA
 biological_processGO:1903181 positive regulation of dopamine biosynthetic process IEA
 biological_processGO:1903364 positive regulation of cellular protein catabolic process IEA
 biological_processGO:1903828 negative regulation of cellular protein localization IEA
 biological_processGO:1905166 negative regulation of lysosomal protein catabolic process IEA
 biological_processGO:1990126 retrograde transport, endosome to plasma membrane IEA
 biological_processGO:2000331 regulation of terminal button organization IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005739 mitochondrion IEA
 cellular_componentGO:0005764 lysosome IEA
 cellular_componentGO:0005768 endosome IEA
 cellular_componentGO:0005769 early endosome IEA
 cellular_componentGO:0005770 late endosome IBA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0010008 endosome membrane IEA
 cellular_componentGO:0014069 postsynaptic density IEA
 cellular_componentGO:0030904 retromer complex IEA
 cellular_componentGO:0030906 retromer, cargo-selective complex IEA
 cellular_componentGO:0043005 neuron projection IEA
 cellular_componentGO:0043025 neuronal cell body IEA
 cellular_componentGO:0048471 perinuclear region of cytoplasm IEA
 cellular_componentGO:0097422 tubular endosome IEA
 cellular_componentGO:0099073 mitochondrion-derived vesicle IEA
 molecular_functionGO:0008565 protein transporter activity IBA
 molecular_functionGO:0031748 D1 dopamine receptor binding IEA


Pathways (from Reactome)
Pathway description
WNT ligand biogenesis and trafficking


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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